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Protein

Tropomyosin

Gene
N/A
Organism
Helix aspersa (Brown garden snail) (Cornu aspersum)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.

Names & Taxonomyi

Protein namesi
Recommended name:
Tropomyosin
Alternative name(s):
Allergen: Hel as 1
OrganismiHelix aspersa (Brown garden snail) (Cornu aspersum)
Taxonomic identifieri6535 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaGastropodaHeterobranchiaEuthyneuraPanpulmonataEupulmonataStylommatophoraSigmurethraHelicoideaHelicidaeHelix

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3309 Hel as 1.0101
378 Hel as 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002056671 – 284TropomyosinAdd BLAST284

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliO97192
SMRiO97192
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1 – 284By similarityAdd BLAST284

Domaini

The molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.

Sequence similaritiesi

Belongs to the tropomyosin family.Curated

Keywords - Domaini

Coiled coil, Repeat

Family and domain databases

InterProiView protein in InterPro
IPR000533 Tropomyosin
PfamiView protein in Pfam
PF00261 Tropomyosin, 1 hit
PRINTSiPR00194 TROPOMYOSIN

Sequencei

Sequence statusi: Complete.

O97192-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAIKKKMLA MKMEKENALD RAEQVEQKLR DCECNKNKVE EDLNNLQKKF
60 70 80 90 100
AILENDFDSI NEQLLDANTK LEASEKKNAE IESETAGLQR RIQLLEEDLE
110 120 130 140 150
RSEERLQSAT EKLEEASKAA DESERGRKVL ESRSLADDER LDGLEAQLKE
160 170 180 190 200
AKYIAEDAER KFDEAARKLA ITEVDLERAE ARLEAAEAKI LELEEELKVV
210 220 230 240 250
GNNMKSLEIS EQEASQREDS YEETIRDLTQ RLKDAENRAS EAERTVSKLQ
260 270 280
KEVDRLEDEL LAEKERYKAT SDELDSTFAE LAGY
Length:284
Mass (Da):32,637
Last modified:May 1, 1999 - v1
Checksum:i01B87021E0F32D4D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y14855 mRNA Translation: CAB38044.1

Similar proteinsi

Entry informationi

Entry nameiTPM_HELAS
AccessioniPrimary (citable) accession number: O97192
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: May 1, 1999
Last modified: May 23, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health