Unreviewed, UniProtKB/TrEMBL O97183 (O97183_DROME)

Names and origin

Protein names

Submitted name:
    RNA polymerase II 33kD subunit, isoform A EMBL AAF53342.1
    EC=2.7.7.6
Submitted name:
    GH07456p EMBL AAL28192.1
    RNA polymerase II p33 subunit EMBL CAB38635.1

Gene names

Name:	RpII33 EMBL AAF53342.1 FlyBase FBgn0026373
Synonyms:	RPB3 EMBL CAB38635.1
ORF Names:	CG7885 FlyBase FBgn0026373, Dmel_CG7885 EMBL AAF53342.1

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	275 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	transcription Inferred from electronic annotation. Source: InterPro
Cellular component	nucleus Inferred from electronic annotation. Source: InterPro
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: InterPro protein dimerization activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O97183-1 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: F2414D4C3BCFC573	FASTA	275	31,243
	10 20 30 40 50 60 MPYANQPSVQ ITELTDDNVK FVLEDTELSV ANSLRRVFIA ETPTLAIDWV QLEANSTVLS 70 80 90 100 110 120 DEFLAHRIGL IPLISDDVVE RLQYTRDCIC LDFCPECSVE FTLDVKCSEE QTRHVTTADL 130 140 150 160 170 180 KSSNAKVLPV TSRNQGEEDN EYGESNDEIL IIKLRKGQEL KLRAYAKKGF GKEHAKWNPT 190 200 210 220 230 240 AGVCFEYDPD NSMRHTLYPK PDEWPKSEHT ELEDDQYEAP YNWEAKPNKF FFNVESAGAL 250 260 270 KPENIVVMGV QVLKNKLSNL QTQLSHESQN DALAV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Li P., Liao G., Miranda A., Mungall C.J., Nunoo J. , Pacleb J., Paragas V., Park S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAL28192.1.
[4]	"The highly compact structure of the mitochondrial DNA polymerase genomic region of Drosophila melanogaster: functional and evolutionary implications." Lefai E., Fernandez-Moreno M.A., Kaguni L.S., Garesse R. Insect Mol. Biol. 9:315-322(2000) [PubMed: 10886416] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014134 Genomic DNA. Translation: AAF53342.1. AY060644 mRNA. Translation: AAL28192.1. AJ133650 mRNA. Translation: CAB38635.1.
RefSeq	NP_477419.1.
UniGene	Dm.3412
3D structure databases
HSSP	HSSP built from PDB template 1I6H based on UniProtKB P16370.
ModBase	Search...
Protein-protein interaction databases
IntAct	O97183. 9 interactions.
Proteomic databases
PRIDE	O97183.
Genome annotation databases
Ensembl	FBgn0026373. Drosophila melanogaster. [Contig view]
GeneID	34796.
KEGG	dme:Dmel_CG7885.
NMPDR	fig|7227.3.peg.2331.
Organism-specific databases
FlyBase	FBgn0026373. RpII33.
Phylogenomic databases
HOGENOM	O97183.
OMA	O97183. MQYSRDC.
Gene expression databases
ArrayExpress	O97183.
Family and domain databases
InterPro	IPR001514. DNA-dir_RNA_pol_30-40kDsu_CS. IPR011261. DNA-dir_RNA_pol_dimersation. IPR011262. DNA-dir_RNA_pol_insert. IPR011263. DNA-dir_RNA_pol_RpoA/D/Rpb3. [Graphical view]
Pfam	PF01000. RNA_pol_A_bac. 1 hit. PF01193. RNA_pol_L. 1 hit. [Graphical view]
SMART	SM00662. RPOLD. 1 hit. [Graphical view]
PROSITE	PS00446. RNA_POL_D_30KD. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	790263.

Entry information

Entry name

O97183_DROME

Accession

Primary (citable) accession number: O97183

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 1999
Last sequence update:	May 1, 1999
Last modified:	June 16, 2009
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)