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O97048 (MA165_PINFU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
N16.5 matrix protein
Alternative name(s):
N14#5
N14#7
Pearlin
OrganismPinctada fucata (Pearl oyster)
Taxonomic identifier50426 [NCBI]
Taxonomic lineageEukaryotaMetazoaLophotrochozoaMolluscaBivalviaPteriomorphiaPterioidaPterioideaPteriidaePinctada

Protein attributes

Sequence length129 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

May be specifically involved in the formation of the nacreous layer By similarity. Ref.3 Ref.4

Subunit structure

Heterooligomer; disulfide-linked. Pif97, Pif80, N16 and other proteins form a complex. Ref.3

Subcellular location

Secretedextracellular spaceextracellular matrix.

Tissue specificity

Component of conchiolin, the organic matrix of nacre. Specifically expressed in mantle epithelium.

Sequence similarities

Belongs to the N16 matrix protein family.

Ontologies

Keywords
   Cellular componentExtracellular matrix
Secreted
   DomainRepeat
Signal
   PTMDisulfide bond
Gene Ontology (GO)
   Cellular_componentproteinaceous extracellular matrix

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential
Chain24 – 129106N16.5 matrix protein
PRO_0000379790

Regions

Repeat91 – 9221
Repeat93 – 9422
Repeat95 – 9623
Repeat97 – 9824
Repeat99 – 10025
Region91 – 100105 X 2 AA tandem repeats of N-G

Sequences

Sequence LengthMass (Da)Tools
O97048 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: 6447712EA0940A9C

FASTA12915,388
        10         20         30         40         50         60 
MTCTLRWTIT ALVLLGICHL ARPAFRTKCG RYSYCWIPYD IERDRYDNGD KKCCFCRNAW 

        70         80         90        100        110        120 
SPWQCKEDER YEWLRCGHKF YYMCCYTDDD NGNGNGNGNG FNYLKSLYGG YGNGNGEFWE 


EYIDERYDK 

« Hide

References

[1]"Complementary DNA cloning and characterization of pearlin, a new class of matrix protein in the nacreous layer of oyster pearls."
Miyashita T., Takagi R., Okushima M., Nakano S., Miyamoto H., Nishikawa E., Matsushiro A.
Mar. Biotechnol. 2:409-418(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Mantle.
[2]"14 kD matrix protein family in nacreous layer of Japanese peal oyster, Pinctada fucata."
Hayashi N., Samata T.
Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Mantle.
[3]"An acidic matrix protein, Pif, is a key macromolecule for nacre formation."
Suzuki M., Saruwatari K., Kogure T., Yamamoto Y., Nishimura T., Kato T., Nagasawa H.
Science 325:1388-1390(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBUNIT, FUNCTION.
[4]"The molecular basis of nacre formation."
Kroger N.
Science 325:1351-1352(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.

Web resources

Protein Spotlight

String of intrusion - Issue 112 of December 2009

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB020779 mRNA. Translation: BAA75626.1.
AB023252 mRNA. Translation: BAA83737.1.
AB023253 mRNA. Translation: BAA83738.1.
AB023254 mRNA. Translation: BAA83739.1.

3D structure databases

ProteinModelPortalO97048.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameMA165_PINFU
AccessionPrimary (citable) accession number: O97048
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 1, 1999
Last modified: February 19, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Protein Spotlight

Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries