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Protein

N16.5 matrix protein

Gene
N/A
Organism
Pinctada fucata (Pearl oyster)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May be specifically involved in the formation of the nacreous layer.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
N16.5 matrix protein
Alternative name(s):
N14#5
N14#7
Pearlin
OrganismiPinctada fucata (Pearl oyster)
Taxonomic identifieri50426 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaBivalviaPteriomorphiaPterioidaPterioideaPteriidaePinctada

Subcellular locationi

GO - Cellular componenti

  1. proteinaceous extracellular matrix Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Extracellular matrix, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence AnalysisAdd
BLAST
Chaini24 – 129106N16.5 matrix proteinPRO_0000379790Add
BLAST

Keywords - PTMi

Disulfide bond

Expressioni

Tissue specificityi

Component of conchiolin, the organic matrix of nacre. Specifically expressed in mantle epithelium.

Interactioni

Subunit structurei

Heterooligomer; disulfide-linked. Pif97, Pif80, N16 and other proteins form a complex.1 Publication

Structurei

3D structure databases

ProteinModelPortaliO97048.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati91 – 9221
Repeati93 – 9422
Repeati95 – 9623
Repeati97 – 9824
Repeati99 – 10025

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni91 – 100105 X 2 AA tandem repeats of N-G

Sequence similaritiesi

Belongs to the N16 matrix protein family.Curated

Keywords - Domaini

Repeat, Signal

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O97048-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTCTLRWTIT ALVLLGICHL ARPAFRTKCG RYSYCWIPYD IERDRYDNGD
60 70 80 90 100
KKCCFCRNAW SPWQCKEDER YEWLRCGHKF YYMCCYTDDD NGNGNGNGNG
110 120
FNYLKSLYGG YGNGNGEFWE EYIDERYDK
Length:129
Mass (Da):15,388
Last modified:May 1, 1999 - v1
Checksum:i6447712EA0940A9C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB020779 mRNA. Translation: BAA75626.1.
AB023252 mRNA. Translation: BAA83737.1.
AB023253 mRNA. Translation: BAA83738.1.
AB023254 mRNA. Translation: BAA83739.1.

Cross-referencesi

Web resourcesi

Protein Spotlight

String of intrusion - Issue 112 of December 2009

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB020779 mRNA. Translation: BAA75626.1.
AB023252 mRNA. Translation: BAA83737.1.
AB023253 mRNA. Translation: BAA83738.1.
AB023254 mRNA. Translation: BAA83739.1.

3D structure databases

ProteinModelPortaliO97048.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "Complementary DNA cloning and characterization of pearlin, a new class of matrix protein in the nacreous layer of oyster pearls."
    Miyashita T., Takagi R., Okushima M., Nakano S., Miyamoto H., Nishikawa E., Matsushiro A.
    Mar. Biotechnol. 2:409-418(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Mantle.
  2. "14 kD matrix protein family in nacreous layer of Japanese peal oyster, Pinctada fucata."
    Hayashi N., Samata T.
    Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Mantle.
  3. "An acidic matrix protein, Pif, is a key macromolecule for nacre formation."
    Suzuki M., Saruwatari K., Kogure T., Yamamoto Y., Nishimura T., Kato T., Nagasawa H.
    Science 325:1388-1390(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBUNIT, FUNCTION.
  4. "The molecular basis of nacre formation."
    Kroger N.
    Science 325:1351-1352(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.

Entry informationi

Entry nameiMA165_PINFU
AccessioniPrimary (citable) accession number: O97048
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 1, 1999
Last modified: January 7, 2015
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. Protein Spotlight
    Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.