EG:23E12.2 protein - Drosophila melanogaster (Fruit fly)

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Unreviewed, UniProtKB/TrEMBL O96833 (O96833_DROME)

Last modified July 7, 2009. Version 49. History...

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information

Names and origin

Protein names

Submitted name:
EG:23E12.2 protein EMBL CAA21413.1

Gene names

Name:	RhoGAP1A FlyBase FBgn0025836
Synonyms:	EG:23E12.2 EMBL CAA21413.1
ORF Names:	CG40494 FlyBase FBgn0025836

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome] EMBL CAA21413.1

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	658 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 PH domain. RuleBase RU003350V0 Spearmint SPM000198

Contains 1 Rho-GAP domain. Spearmint SPM000198

Ontologies

Keywords
Molecular function	GTPase activation Spearmint SPM000198
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	regulation of Rho protein signal transduction Inferred from electronic annotation. Source: InterPro
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	Rho guanyl-nucleotide exchange factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

O96833-1 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: 5675FC5D1A8E1A14
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658

75,067

        10         20         30         40         50         60 
MQYKKAIHAT LTTSQPVIRE EEENTIFFKI DELYDLHTGF LSDLKTIVSH EGGDVLIGEP 

        70         80         90        100        110        120 
FRRLAEMFDL YSAFLHNYKN AIETVKKCSA NNPQFKKIVS TIVLNLQTEQ SLTLEDLLHK 

       130        140        150        160        170        180 
PVARVQINAL VFNDLLRETP NAHPDHQPLR QAQKIIQMFL NQFNVVNQRL PIESNRNLRR 

       190        200        210        220        230        240 
MVRNSFIVEL VDGHRKLRHL FLFNDVIACA KYKALGRDRI DYELKWFIPL KDVSIYEEAD 

       250        260        270        280        290        300 
PAVELKESSP ANISQVKRNL RSVRDQLAME VANSGSGGFR SGDKYRRKLA DLESQLVLAT 

       310        320        330        340        350        360 
PNLVLRLGNK ANNKTITFFL SSDFERTQWI DSILSLKQKC NLPGANTINS LEVTAFIVAM 

       370        380        390        400        410        420 
QKGMKTEMGS YLMRNTNDES LLVGDLYMGV HGLEGLEQAN DLYICVEVDS YGHYFRKATT 

       430        440        450        460        470        480 
KKICRSQTPL WNESFMLELE GSQNVRILLY EAKERPLLKA KHILKVGVKS ACIREVERRG 

       490        500        510        520        530        540 
MLEVGCYRVS GSASDLAKLK KAFESGEYMA LMDAYEAEQL LREVDIHSVT GILKTFLREL 

       550        560        570        580        590        600 
PEALFTDQLY PRFFDTFSAF SNNNESTRIN ELLKVFEELP QANKASITSI LDHLIRVHEK 

       610        620        630        640        650 
ETDNKMSLHN LAMVFGPTLL RPGQTQVKQK DPLAASTVDV MAQAGILYCF LQARIKKD

References

[1]	"Sequencing the distal X chromosome of Drosophila melanogaster." Madueno E., de Pablos B., Modolell J. Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	Benos P. Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
	AL031884 Genomic DNA. Translation: CAA21413.1.
3D structure databases
HSSP	HSSP built from PDB template 1F7C based on UniProtKB Q98935.
ModBase	Search...
Proteomic databases
PRIDE	O96833.
Genome annotation databases
Ensembl	FBgn0025836. Drosophila melanogaster. [Contig view]
Organism-specific databases
FlyBase	FBgn0025836. RhoGAP1A.
Gene expression databases
ArrayExpress	O96833.
Family and domain databases
InterPro	IPR000008. C2_Ca-dep. IPR000219. DH-domain. IPR001849. Pleckstrin_homology. IPR000198. RhoGAP. [Graphical view]
Gene3D	G3DSA:1.10.555.10. RhoGAP. 1 hit. G3DSA:1.20.900.10. RhoGEF. 1 hit.
Pfam	PF00169. PH. 1 hit. PF00620. RhoGAP. 1 hit. PF00621. RhoGEF. 1 hit. [Graphical view]
SMART	SM00239. C2. 1 hit. SM00233. PH. 1 hit. SM00324. RhoGAP. 1 hit. SM00325. RhoGEF. 1 hit. [Graphical view]
PROSITE	PS50010. DH_2. 1 hit. PS50003. PH_DOMAIN. 1 hit. PS50238. RHOGAP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O96833_DROME

Accession

Primary (citable) accession number: O96833

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 1999
Last sequence update:	May 1, 1999
Last modified:	July 7, 2009
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information