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O96764

- TPM_CHIKI

UniProt

O96764 - TPM_CHIKI

Protein

Tropomyosin

Gene
N/A
Organism
Chironomus kiiensis (Midge)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 33 (01 Oct 2014)
      Sequence version 2 (01 Oct 2000)
      Previous versions | rss
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    Functioni

    Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Tropomyosin
    Alternative name(s):
    Allergen: Chi k 10
    OrganismiChironomus kiiensis (Midge)
    Taxonomic identifieri84408 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraChironomoideaChironomidaeChironominaeChironomus

    Pathology & Biotechi

    Allergenic propertiesi

    Causes an allergic reaction in human.

    Keywords - Diseasei

    Allergen

    Protein family/group databases

    Allergomei200. Chi k 10.
    3191. Chi k 10.0101.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 285285TropomyosinPRO_0000205683Add
    BLAST

    Proteomic databases

    PRIDEiO96764.

    Interactioni

    Subunit structurei

    Homodimer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliO96764.
    SMRiO96764. Positions 1-281.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili1 – 285285By similarityAdd
    BLAST

    Domaini

    The molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.

    Sequence similaritiesi

    Belongs to the tropomyosin family.Curated

    Keywords - Domaini

    Coiled coil, Repeat

    Family and domain databases

    InterProiIPR000533. Tropomyosin.
    [Graphical view]
    PfamiPF00261. Tropomyosin. 1 hit.
    [Graphical view]
    PRINTSiPR00194. TROPOMYOSIN.
    PROSITEiPS00326. TROPOMYOSIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O96764-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDAIKKKMQA MKLEKDNALD RALLCENQAR DANLRAEKAE EEARTLQKKI    50
    QTIENDLDQT QGQETLVNGK LEGKEKALQN AESEVAALNR RIQLLGEDLD 100
    RSEERLASAT AKLSEASAAA DESERARKIL ENRSLADEER MDALENQLKE 150
    ARFLAEEADK KYDEVARKLA MVEADLERAE ERAEAGEAKI VELEEELRVV 200
    GNNLKSLEVS EEKANQREEE YKNQIKTLTT RLKEAEARAE FAERSVQKLQ 250
    KEVDRLEDEL VSEKEKYREI GDDLDTAFVE LILKE 285
    Length:285
    Mass (Da):32,533
    Last modified:October 1, 2000 - v2
    Checksum:iDCA3FE9C05809FF4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ012184 mRNA. Translation: CAA09938.2.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ012184 mRNA. Translation: CAA09938.2 .

    3D structure databases

    ProteinModelPortali O96764.
    SMRi O96764. Positions 1-281.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    Allergomei 200. Chi k 10.
    3191. Chi k 10.0101.

    Proteomic databases

    PRIDEi O96764.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR000533. Tropomyosin.
    [Graphical view ]
    Pfami PF00261. Tropomyosin. 1 hit.
    [Graphical view ]
    PRINTSi PR00194. TROPOMYOSIN.
    PROSITEi PS00326. TROPOMYOSIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning of Chironomus kiiensis tropomyosin gene."
      Yong T.S.
      Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiTPM_CHIKI
    AccessioniPrimary (citable) accession number: O96764
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 16, 2004
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 33 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Documents

    1. Allergens
      Nomenclature of allergens and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3