O96763 (O96763_TRYCR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Tryparedoxin peroxidase EMBL AAF04974.1

Submitted name:
Tryparedoxin peroxidase homologue EMBL CAA09922.1

Gene names

Name:

Tryp EMBL AAF04974.1

Organism

Trypanosoma cruzi EMBL CAA09922.1

Taxonomic identifier

5693 [NCBI]

Taxonomic lineage

Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Trypanosoma › Schizotrypanum

Protein attributes

Sequence length	199 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Oxidoreductase Peroxidase EMBL CAA09922.1
Technical term	3D-structure PDB 1UUL
Gene Ontology (GO)
Molecular function	peroxidase activity Inferred from electronic annotation. Source: UniProtKB-KW peroxiredoxin activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O96763 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 17C847ED17FA06A5	FASTA	199	22,404
	10 20 30 40 50 60 MSCGDAKLNH PAPDFNETAL MPNGTFKKVA LTSYKGKWLV LFFYPMDFTF VCPTEICQFS 70 80 90 100 110 120 DRVKEFSDIG CEVLACSMDS EYSHLAWTSI ERKRGGLGQM NIPILADKTK CIMKSYGVLK 130 140 150 160 170 180 EEDGVAYRGL FIIDPKQNLR QITVNDLPVG RDVDEALRLV KAFQFVEKHG EVCPANWKPG 190 DKTMKPDPEK SKEYFGAVA

References

[1]	"Distinct mitochondrial and cytosolic enzymes mediate trypanothione-dependent peroxide metabolism in Trypanosoma cruzi." Wilkinson S.R., Temperton N.J., Mondragon A., Kelly J.M. J. Biol. Chem. 275:8220-8225(2000) [PubMed: 10713147] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: CL-Brener EMBL CAA09922.1.
[2]	"Crystal structure of the tryparedoxin peroxidase from the human parasite Trypanosoma cruzi." Pineyro M.D., Pizarro J.C., Lema F., Pritsch O., Cayota A., Bentley G.A., Robello C. J. Struct. Biol. 150:11-22(2005) [PubMed: 15797726] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS).
[3]	"Cloning and characterization of the trypanothione-dependent peroxidase system of Trypanosoma cruzi." Tetaud E., Fairlamb A.H. Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: CL Brener EMBL AAF04974.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF106856 mRNA. Translation: AAF04974.1.
AJ012101 Genomic DNA. Translation: CAA09922.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1UUL	X-ray	2.80	A/B/C/D/E/F/G/H/I/J	1-199	[»]

ProteinModelPortal

O96763.

SMR

O96763. Positions 4-197.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

KEGG

tcr:487507.10.
tcr:505983.9.
tcr:509445.10.

Phylogenomic databases

PhylomeDB

O96763.

ProtClustDB

PTZ00253.

Family and domain databases

InterPro

IPR000866. AhpC/TSA.
IPR024706. Peroxiredoxin_AhpC-typ.
IPR019479. Peroxiredoxin_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]

Gene3D

G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.

KO

K11185.

Pfam

PF10417. 1-cysPrx_C. 1 hit.
PF00578. AhpC-TSA. 1 hit.
[Graphical view]

PIRSF

PIRSF000239. AHPC. 1 hit.

SUPFAM

SSF52833. Thiordxn-like_fd. 1 hit.

PROSITE

PS51352. THIOREDOXIN_2. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

O96763_TRYCR

Accession

Primary (citable) accession number: O96763

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 1999
Last sequence update:	May 1, 1999
Last modified:	December 14, 2011
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)