Unreviewed, UniProtKB/TrEMBL O96689 (O96689_DROME)

Names and origin

Protein names

Submitted name:
    Rad21 EMBL EAA46289.1
Submitted name:
    Rad21 mitotic cohesin EMBL AAD04175.1

Gene names

Name:	vtd FlyBase FBgn0260987
Synonyms:	Rad21 FlyBase FBgn0026057, drad21 EMBL AAD04175.1
ORF Names:	CG17436 FlyBase FBgn0026057, Dmel_CG17436 EMBL EAA46289.1

Organism

Drosophila melanogaster (Fruit fly) EMBL AAD04175.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	715 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

Ontologies

Gene Ontology (GO)
Biological process	mitotic sister chromatid cohesion Non-traceable author statement. Source: FlyBase mitotic spindle organization Inferred from mutant phenotype. Source: FlyBase
Cellular component	centromeric heterochromatin Inferred from direct assay. Source: FlyBase cohesin complex Non-traceable author statement. Source: FlyBase nuclear chromosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O96689-1 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 5E457E71B410DEE5	FASTA	715	79,945
	10 20 30 40 50 60 MFYEHIILAK KGPLARIWLA AHWDKKITKA HVFETNIEKS VEGILQPKVK LALRTSGHLL 70 80 90 100 110 120 LGVVRIYSRK AKYLLADCNE AFVKIKMAFR PGMVDLPEGH REANVNAITL PEVFHDFDTA 130 140 150 160 170 180 LPELNDIDIE AQFSINQSRA DEITMREDYG SLSLSLQDDG FGDIGFEAET PEIIRCSIPS 190 200 210 220 230 240 NINDKIFDND VLENIESLDP HSLDAHADMP GSRLDGDGFG DSFGQPALFE DDLFGDPSQP 250 260 270 280 290 300 VEQITKESTT VLNADDSDED AIDNIHNVPS PATSLVNSIE DEKEENNLNG HASVSENVPM 310 320 330 340 350 360 NEITLVQNED EGFALAPLDV SMYKGVTKAK RKRKLIIDEI KNISGEEMKA QLADTSDILT 370 380 390 400 410 420 TLDLAPPTKR LMYWKETGGV EKLFSLPSRS IPARALFGNY NRQLFSHSTF FEDFSSVVPM 430 440 450 460 470 480 EILALEFYTK ENENALIIFN KKGRKRKNDN MSNLFLDHVP DSVVQSLEAP EVLRANHKSL 490 500 510 520 530 540 GVSTVSVEIV SKEQESISCQ NELTFFDNMR SPDLLSLNEM EQFSSINELP LTPRNMNHEM 550 560 570 580 590 600 GDDFNQGDST PAGLDHGHAT PQHGNIGEMD HDSVIPTKKT AVILNESVGT SVLSDNGVSK 610 620 630 640 650 660 RTNNILKGWD NYEIPSFVGQ NHGDEQMENE TDEQFEERVL NKRAAHLFID VRAHFIAKDS 670 680 690 700 710 LELSQLTSGN SRKQAAQKFY SLLVLKKFKV LHIDQSAPYA DITITRGPTF ENPKI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genetic studies of the rad21/scc1/mcd1 cohesin in Drosophila." Warren W.D., Vuong T. Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Phosphoproteome analysis of Drosophila melanogaster embryos." Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P. J. Proteome Res. 7:1675-1682(2008) [PubMed: 18327897] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.
[3]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[4]	"Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence." Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., Pacleb J.M., Park S. , Pfeiffer B.D., Richards S., Sodergren E.J., Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M. Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002) [PubMed: 12537568] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[5]	"Heterochromatic sequences in a Drosophila whole-genome shotgun assembly." Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., Karpen G.H. Genome Biol. 3:RESEARCH0085.1-RESEARCH0085.16(2002) [PubMed: 12537574] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[6]	"The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective." Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J.W., Svirskas R., Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M., Celniker S.E. Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002) [PubMed: 12537573] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[7]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[8]	"Combined evidence annotation of transposable elements in genome sequences." Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., Ashburner M., Anxolabehere D. PLoS Comput. Biol. 1:166-175(2005) [PubMed: 16110336] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[9]	"The Release 5.1 annotation of Drosophila melanogaster heterochromatin." Smith C.D., Shu S., Mungall C.J., Karpen G.H. Science 316:1586-1591(2007) [PubMed: 17569856] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[10]	"Sequence finishing and mapping of Drosophila melanogaster heterochromatin." Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M., Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A., Dimitri P., Karpen G.H., Celniker S.E. Science 316:1625-1628(2007) [PubMed: 17569867] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[11]	Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S., Svirskas R., Rubin G. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[12]	Drosophila Heterochromatin Genome Project Smith C.D., Shu S., Mungall C.J., Karpen G.H. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[13]	FlyBase Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[14]	"Drad21, a Drosophila rad21 homologue expressed in S-phase cells." Warren W.D., Lin E., Nheu T.V., Hime G.R., McKay M.J. Gene 250:77-84(2000) [PubMed: 10854781] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF109926 mRNA. Translation: AAD04175.1. AF267746, AF267745 Genomic DNA. Translation: AAF82099.1. CM000458 Genomic DNA. Translation: EAA46289.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:18950N.
IntAct	O96689. 1 interaction.
Proteomic databases
PRIDE	O96689.
Genome annotation databases
Ensembl	FBgn0026057. Drosophila melanogaster. [Contig view]
NMPDR	fig|7227.3.peg.19005.
Organism-specific databases
FlyBase	FBgn0260987. vtd.
Phylogenomic databases
HOGENOM	O96689.
OMA	O96689. RADEITM.
Gene expression databases
ArrayExpress	O96689.
Family and domain databases
InterPro	IPR006909. Rad21/Rec8_C. IPR006910. Rad21_Rec8_N. [Graphical view]
Pfam	PF04824. Rad21_Rec8. 1 hit. PF04825. Rad21_Rec8_N. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O96689_DROME

Accession

Primary (citable) accession number: O96689

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 1999
Last sequence update:	May 1, 1999
Last modified:	July 7, 2009
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)