O96608 (O96608_TRYCR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
SERCA-type calcium-ATPase EMBL AAD08694.1

Gene names

Name:

sca1 EMBL AAD08694.1

Organism

Trypanosoma cruzi EMBL AAD08694.1

Taxonomic identifier

5693 [NCBI]

Taxonomic lineage

Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Trypanosoma › Schizotrypanum

Protein attributes

Sequence length	1006 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the cation transport ATPase (P-type) family. RuleBase RU000653

Ontologies

Keywords
Biological process	Ion transport SAAS SAAS023300 Transport
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS004014
Ligand	ATP-binding SAAS SAAS004014 RuleBase RU000653 Nucleotide-binding
Molecular function	Hydrolase RuleBase RU000653 SAAS SAAS004014
PTM	Phosphoprotein SAAS SAAS004014 RuleBase RU000653
Gene Ontology (GO)
Biological process	ATP biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW calcium-transporting ATPase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O96608 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 99F678DA80FF7D2D	FASTA	1,006	109,731
	10 20 30 40 50 60 MALLSLPATP STMDASAVTK CVRVDAKRGL PADEVEERRR QFGTNELPTK PSTPFWKLIL 70 80 90 100 110 120 AQFEDTLVRI LLFAAMTSFV MALFEKNAGD FVEPFIILLI LVLNATVGVW QENRAESAIE 130 140 150 160 170 180 ALKSFVPKTA VVLREGKLVT VGAENLVPAD IVEVSVGNRV PADMRVLELH STTLRADQAI 190 200 210 220 230 240 LNGESVEAIK EADAAIGHQD RFPSSMVYSG TSIVYGKAQC VVVRTGAFTE IGSIERDVRE 250 260 270 280 290 300 QEEVKTPLQI KLDEFGMLLS KVIGYTCLAV FVINMVRWYS VHTPTPDEPW YERFIAPAIH 310 320 330 340 350 360 CLKVAIALAV AAIPEGLPAV VTTCLALGTR RMARHNALVR DLPSVETSAG GTVIWSDKTG 370 380 390 400 410 420 TLTTDMMSVM EIFTLGLDGN PREYELKDSR FNVMPNVVTC GGKPVTSALE TDGALSMLTN 430 440 450 460 470 480 IAVLCNDASL HYNTTNGQVE KIGEATEAAL LVMSEKLAHA TDPTAVCAFR KLAEQKWKKN 490 500 510 520 530 540 TTLEFTRQRK SMSEHATSTA GAKLNSLFVK GAPEEVLRRS THVMQVDGVV IPLSDALRSR 550 560 570 580 590 600 IIAEIDAMSG SEHALRCIGF AFKSTQPVRE LKLSDPSTFE QIESDLTFVG ACGMLDPPRA 610 620 630 640 650 660 EVREAIDNCR TAGIRVVVIT GDRKETAEAI CRKLGLLLKT ETSGLSYTGA EFEGMNPAEK 670 680 690 700 710 720 RKAVMSAVLF SRTDPSHKMQ LVKLLQEQKL ICARTGDGVN DAPALKKADI GIAMGSGTQV 730 740 750 760 770 780 AKAASKMVLA EDNFATVVKA VGEGRAIFNN TKQFIRYLIS SNIGEVACIL LTGLCGLPEA 790 800 810 820 830 840 LSPVQLLWVN LVTDGFPATA FGFNAPDEDI MQQPPRHVDE PIVNGWMFLR YMVIGVYVGL 850 860 870 880 890 900 ATIGGFLWWF LSHGFNWKDL TTYAACTDMQ DAKCAILADP ETARAIALSI LVLVEMLNAL 910 920 930 940 950 960 NALSENASLI TARPSSNIWL LLAIFSSLAL HLMIMYVPFL AALFNIAPLG VDPLIVKEAQ 970 980 990 1000 PFSVLVPSNF DDWKAVIVFS VPVIFIDELL KYITRHMQAS RNKKNN

References

[1]	"TcSCA complements yeast mutants defective in Ca2+ pumps and encodes a Ca2+-ATPase that localizes to the endoplasmic reticulum of Trypanosoma cruzi." Furuya T., Okura M., Ruiz F.A., Scott D.A., Docampo R. J. Biol. Chem. 276:32437-32445(2001) [PubMed: 11382780] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Y-NIH EMBL AAD08694.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF093566 Genomic DNA. Translation: AAD08694.1.
3D structure databases
HSSP	HSSP built from PDB template 1SU4 based on UniProtKB P04191.
ProteinModelPortal	O96608.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR023306. ATPase_cation_domN. IPR008250. ATPase_P-typ_ATPase-assoc-dom. IPR005782. ATPase_P-typ_Ca-transp. IPR006068. ATPase_P-typ_cation-transptr_C. IPR004014. ATPase_P-typ_cation-transptr_N. IPR023300. ATPase_P-typ_cyto_domA. IPR023299. ATPase_P-typ_cyto_domN. IPR001757. ATPase_P-typ_ion-transptr. IPR018303. ATPase_P-typ_P_site. IPR023298. ATPase_P-typ_TM_dom. IPR005834. Dehalogen-like_hydro. IPR023214. HAD-like_dom. [Graphical view]
Gene3D	G3DSA:2.70.150.10. ATPase_P-typ_cyto_domA. 2 hits. G3DSA:3.40.1110.10. ATPase_P-typ_cyto_domN. 1 hit. G3DSA:1.20.1110.10. ATPase_P-typ_TM_dom. 2 hits.
Pfam	PF00689. Cation_ATPase_C. 1 hit. PF00690. Cation_ATPase_N. 1 hit. PF00122. E1-E2_ATPase. 1 hit. PF00702. Hydrolase. 1 hit. [Graphical view]
PRINTS	PR00119. CATATPASE.
SMART	SM00831. Cation_ATPase_N. 1 hit. [Graphical view]
SUPFAM	SSF81660. ATPase_cation_domN. 1 hit. SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01116. ATPase-IIA1_Ca. 1 hit. TIGR01494. ATPase_P-type. 2 hits.
PROSITE	PS00154. ATPASE_E1_E2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O96608_TRYCR

Accession

Primary (citable) accession number: O96608

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 1999
Last sequence update:	May 1, 1999
Last modified:	September 21, 2011
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)