O96527 (O96527_SCHMA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Calcium ATPase 2 EMBL AAC72756.1

Gene names

Name:

SMA2 EMBL AAC72756.1

Organism

Schistosoma mansoni (Blood fluke) EMBL AAC72756.1

Taxonomic identifier

6183 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Platyhelminthes › Trematoda › Digenea › Strigeidida › Schistosomatoidea › Schistosomatidae › Schistosoma

Protein attributes

Sequence length	1011 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the cation transport ATPase (P-type) family. RuleBase RU000653

Ontologies

Keywords
Biological process	Ion transport SAAS SAAS023300 Transport
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS004014
Ligand	ATP-binding SAAS SAAS004014 RuleBase RU000653 Nucleotide-binding
Molecular function	Hydrolase RuleBase RU000653 SAAS SAAS004014
PTM	Phosphoprotein SAAS SAAS004014 RuleBase RU000653
Gene Ontology (GO)
Biological process	ATP biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW calcium-transporting ATPase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O96527 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 59B2D56293F5C7CA	FASTA	1,011	111,527
	10 20 30 40 50 60 METAFSKTVD EVLHHFESDP ENGLSDEQIK KQTAKFGPNE LPAEESKAIW QLVLEQFDDL 70 80 90 100 110 120 LVKILLMAAI ISFVLALFEE NEESISAFVE PLVILLILIA NAVIGVWQER NAESAIEALK 130 140 150 160 170 180 EYEPEIAKVF RKSHYGIQRI KARELVPGDI VEVSVGDKVP ADMRIIKIMS TTLRVDQSIL 190 200 210 220 230 240 TGESVSVIKF TDAVPDPRAV NQDKKNILFS GTNIAAGKAR GIVVSTGLMT EIGKIRNQMM 250 260 270 280 290 300 DTEPDKTPLQ QKLDEFGQQL SKVISIICVA VWAINIGHFN DPAHGGSWLK GAIYYFKIAV 310 320 330 340 350 360 ALAVAAIPEG LPAVITTCLA LGTRRMAAKN AIVRSLPSVE TLGCTSVICS DKTGTLTTNQ 370 380 390 400 410 420 MSVCRMFIFS KADDKAPEVH HFEITGSKYA PEGEVFLNGQ KVESGEYDGL VEVANICAMC 430 440 450 460 470 480 NDSAIDYNET KHVYEKVGEA TETALCCLVE KMNVYKTSKS GLSKKDLSMV CNHQIQAMWN 490 500 510 520 530 540 KEFTLEFSRD RKSMSVYLQV KPAFASKVPN TAGSGETGPR MFVKGAPEGV LDRCTFVRIG 550 560 570 580 590 600 NKKVPMTPPL KAEIVKHVAS YGTGRDTLRC LALATCDAPV NKAQMDLEDS TKFVKYEQNL 610 620 630 640 650 660 TFVGVVGMLD PPRMEVFDSI ARCRKSGIRV IMITGDNKAT AEAICRRIGI FSEDEPTTGK 670 680 690 700 710 720 SFTGREFDAL PIEEQREACR RARLFARVEP MHKSKIVEFL QEDGEVSAMT GDGVNDAPAL 730 740 750 760 770 780 KKAEIGIAMG SGTAVAKSAA DMVLADDNFN SIVLAVEEGR AIYNNMKQFI RYLISSNIGE 790 800 810 820 830 840 VVSIFLTAAL GLPEALIPVQ LLWVNLVTDG LPATALGFNP PDLDIMERPP RNIKDPLISG 850 860 870 880 890 900 WLFFRYVAIG VYVGCATVGA AAWWFSLYPK GPQLNYYQLT HHMQCLAEKD NFHGIDCHIF 910 920 930 940 950 960 ENPKPMTMAL SVLVLIEMFN ALNSLSENQS LVAMPPWVNI WLVLAMIVSM SLHFLILEVE 970 980 990 1000 1010 FLSKVFQITP LSLEEWFMVI KISAPVIFID EILKLIARRF TDVPSTVGEL K

References

[1]	"Schistosoma mansoni Ca2+-ATPase SMA2 restores viability to yeast Ca2+-ATPase-deficient strains and functions in calcineurin-mediated Ca2+ tolerance." Talla E., de Mendonca R.L., Degand I., Goffeau A., Ghislain M. J. Biol. Chem. 273:27831-27840(1998) [PubMed: 9774393] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Puerto Rican EMBL AAC72756.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF074400 mRNA. Translation: AAC72756.1.
3D structure databases
HSSP	HSSP built from PDB template 1SU4 based on UniProtKB P04191.
ProteinModelPortal	O96527.
SMR	O96527. Positions 1-1002.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR023306. ATPase_cation_domN. IPR008250. ATPase_P-typ_ATPase-assoc-dom. IPR005782. ATPase_P-typ_Ca-transp. IPR006068. ATPase_P-typ_cation-transptr_C. IPR004014. ATPase_P-typ_cation-transptr_N. IPR023300. ATPase_P-typ_cyto_domA. IPR023299. ATPase_P-typ_cyto_domN. IPR001757. ATPase_P-typ_ion-transptr. IPR018303. ATPase_P-typ_P_site. IPR023298. ATPase_P-typ_TM_dom. IPR005834. Dehalogen-like_hydro. IPR023214. HAD-like_dom. [Graphical view]
Gene3D	G3DSA:2.70.150.10. ATPase_P-typ_cyto_domA. 2 hits. G3DSA:3.40.1110.10. ATPase_P-typ_cyto_domN. 1 hit. G3DSA:1.20.1110.10. ATPase_P-typ_TM_dom. 2 hits.
Pfam	PF00689. Cation_ATPase_C. 1 hit. PF00690. Cation_ATPase_N. 1 hit. PF00122. E1-E2_ATPase. 1 hit. PF00702. Hydrolase. 1 hit. [Graphical view]
PRINTS	PR00119. CATATPASE.
SMART	SM00831. Cation_ATPase_N. 1 hit. [Graphical view]
SUPFAM	SSF81660. ATPase_cation_domN. 1 hit. SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01116. ATPase-IIA1_Ca. 1 hit. TIGR01494. ATPase_P-type. 2 hits.
PROSITE	PS00154. ATPASE_E1_E2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O96527_SCHMA

Accession

Primary (citable) accession number: O96527

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 1999
Last sequence update:	May 1, 1999
Last modified:	November 16, 2011
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)