O96525 (O96525_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Unpaired protein EMBL AAC69620.1

Gene names

Name:	os FlyBase FBgn0004956
Synonyms:	unpaired EMBL AAC69620.1

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	413 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological process	JAK-STAT cascade Traceable author statement. Source: FlyBase apical constriction Inferred from mutant phenotype. Source: FlyBase blastoderm segmentation Traceable author statement. Source: FlyBase border follicle cell migration Inferred from mutant phenotype. Source: FlyBase compound eye morphogenesis Inferred from mutant phenotype. Source: FlyBase embryonic development via the syncytial blastoderm Traceable author statement. Source: FlyBase eye-antennal disc morphogenesis Inferred from mutant phenotype. Source: FlyBase foregut morphogenesis Inferred from mutant phenotype. Source: FlyBase germ-line stem cell division Traceable author statement. Source: FlyBase hindgut morphogenesis Inferred from mutant phenotype. Source: FlyBase long-term memory Inferred from mutant phenotype. Source: FlyBase mediolateral intercalation Inferred from mutant phenotype. Source: FlyBase paracrine signaling Inferred from direct assay. Source: FlyBase positive regulation of JAK-STAT cascade Inferred from direct assay. Source: FlyBase regulation of embryonic cell shape Inferred from mutant phenotype. Source: FlyBase sex determination, establishment of X:A ratio Non-traceable author statement. Source: FlyBase somatic stem cell division Traceable author statement. Source: FlyBase
Cellular component	apical part of cell Inferred from direct assay. Source: FlyBase extracellular space Inferred from direct assay. Source: FlyBase proteinaceous extracellular matrix Traceable author statement. Source: FlyBase
Molecular function	cytokine activity Traceable author statement. Source: FlyBase morphogen activity Non-traceable author statement. Source: FlyBase
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O96525 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: C987C3599AD5EFE5	FASTA	413	46,926
	10 20 30 40 50 60 MARPLLLLLP ILLVLLLAAQ LPHLAEGRST TSSGGLTVID SERLPIRTTS STASAQHPNQ 70 80 90 100 110 120 GTIPASAASP RKRHRKRNSN WIDYRNFDEN TTALEWANPC GGNYHPSAGD RFNRQRPRQS 130 140 150 160 170 180 FNQLKRHAFR EYRSLNSSQD SAIDIRNMTM WSLHTHNYKF LPKLKPNSTI ALKRWYRNMQ 190 200 210 220 230 240 TYVASFAYLR RQQIRWDQRS ITRESSTARE LRELLLSSRR ILCELETAVN QTQSPRQKQR 250 260 270 280 290 300 RSGAAVTAVG GTTMLGQQLP QISRLEMNKR LKLRSKTSGP GMGGAASSAS MAAGEADSID 310 320 330 340 350 360 MRFVKHHYYD FLRTMYQLLR RDGKRVRSRP RKHHKKQQRS QKKLLQQQQQ LADQLEQRWR 370 380 390 400 410 SSTLNGKEFN EVSKPVAGGA AGVADVAGVS GGGSNQFARG RRGKRQSKRV QRT

References

[1]	"Drosophila unpaired encodes a secreted protein that activates the JAK signaling pathway." Harrison D.A., McCoon P.E., Binari R., Gilman M., Perrimon N. Genes Dev. 12:3252-3263(1998) [PubMed: 9784499] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF072823 mRNA. Translation: AAC69620.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	O96525.
Proteomic databases
PRIDE	O96525.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0004956. os.
Phylogenomic databases
InParanoid	O96525.
OrthoDB	EOG4Z08N7.
Gene expression databases
ArrayExpress	O96525.
Bgee	O96525.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

O96525_DROME

Accession

Primary (citable) accession number: O96525

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 1999
Last sequence update:	May 1, 1999
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)