ID   O96496_9HEMI            Unreviewed;       352 AA.
AC   O96496;
DT   01-MAY-1999, integrated into UniProtKB/TrEMBL.
DT   01-MAY-1999, sequence version 1.
DT   16-JUN-2009, entry version 61.
DE   SubName: Full=NADP(H)-dependent ketose reductase;
OS   Bemisia argentifolii (silverleaf whitefly).
OC   Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Aleyrodiformes;
OC   Aleyrodoidea; Aleyrodidae; Aleyrodinae; Bemisia.
OX   NCBI_TaxID=77855;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   MEDLINE=99212467; PubMed=10196734; DOI=10.1016/S0965-1748(98)00114-3;
RA   Wolfe G.R., Smith C.A., Hendrix D.L., Salvucci M.E.;
RT   "Molecular basis for thermoprotection in Bemisia: structural
RT   differences between whitefly ketose reductase and other medium-chain
RT   dehydrogenases/reductases.";
RL   Insect Biochem. Mol. Biol. 29:113-120(1999).
RN   [2]
RP   X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS).
RX   MEDLINE=21136510; PubMed=11237597; DOI=10.1006/jmbi.2000.4381;
RA   Banfield M.J., Salvucci M.E., Baker E.N., Smith C.A.;
RT   "Crystal structure of the NADP(H)-dependent ketose reductase from
RT   Bemisia argentifolii at 2.3 A resolution.";
RL   J. Mol. Biol. 306:239-250(2001).
CC   -!- COFACTOR: Zinc (By similarity).
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DR   EMBL; AF067126; AAD02817.1; -; mRNA.
DR   PDB; 1E3J; X-ray; 2.30 A; A=1-352.
DR   PDBsum; 1E3J; -.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:InterPro.
DR   InterPro; IPR013154; ADH_GroES-like.
DR   InterPro; IPR002085; ADH_SF_Zn.
DR   InterPro; IPR013149; ADH_Zn-bd.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   PANTHER; PTHR11695; ADH_Sf_Zn; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   1: Evidence at protein level;
KW   Metal-binding; Oxidoreductase; Zinc.
SQ   SEQUENCE   352 AA;  38164 MW;  56360D3D2EDA6D26 CRC64;
     MASDNLSAVL YKQNDLRLEQ RPIPEPKEDE VLLQMAYVGI CGSDVHYYEH GRIADFIVKD
     PMVIGHEASG TVVKVGKNVK HLKKGDRVAV EPGVPCRRCQ FCKEGKYNLC PDLTFCATPP
     DDGNLARYYV HAADFCHKLP DNVSLEEGAL LEPLSVGVHA CRRAGVQLGT TVLVIGAGPI
     GLVSVLAAKA YGAFVVCTAR SPRRLEVAKN CGADVTLVVD PAKEEESSII ERIRSAIGDL
     PNVTIDCSGN EKCITIGINI TRTGGTLMLV GMGSQMVTVP LVNACAREID IKSVFRYCND
     YPIALEMVAS GRCNVKQLVT HSFKLEQTVD AFEAARKKAD NTIKVMISCR QG
//