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Protein

Integrin beta

Gene
N/A
Organism
Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IntegrinUniRule annotationSAAS annotationImported

Keywords - Biological processi

Cell adhesionUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Integrin betaUniRule annotation
OrganismiBiomphalaria glabrata (Bloodfluke planorb) (Freshwater snail)Imported
Taxonomic identifieri6526 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaGastropodaHeterobranchiaEuthyneuraPanpulmonataHygrophilaPlanorboideaPlanorbidaeBiomphalaria

Subcellular locationi

  • Membrane UniRule annotation; Single-pass type I membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei719 – 74123HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818Sequence analysisAdd
BLAST
Chaini19 – 788770Integrin betaSequence analysisPRO_5004161129Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliO96444.
SMRiO96444. Positions 742-785.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini32 – 456425INBInterPro annotationAdd
BLAST
Domaini636 – 71883Integrin_B_tailInterPro annotationAdd
BLAST
Domaini742 – 78847Integrin_b_cytInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the integrin beta chain family.UniRule annotation
Contains VWFA domain.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

Gene3Di3.40.50.410. 1 hit.
InterProiIPR013111. EGF_extracell.
IPR015812. Integrin_bsu.
IPR014836. Integrin_bsu_cyt_dom.
IPR002369. Integrin_bsu_N.
IPR012896. Integrin_bsu_tail.
IPR032695. Integrin_dom.
IPR016201. Plexin-like_fold.
IPR002035. VWF_A.
[Graphical view]
PANTHERiPTHR10082. PTHR10082. 1 hit.
PfamiPF07974. EGF_2. 1 hit.
PF08725. Integrin_b_cyt. 1 hit.
PF07965. Integrin_B_tail. 1 hit.
PF00362. Integrin_beta. 1 hit.
[Graphical view]
PIRSFiPIRSF002512. Integrin_B. 1 hit.
PRINTSiPR01186. INTEGRINB.
SMARTiSM00187. INB. 1 hit.
SM01241. Integrin_b_cyt. 1 hit.
SM01242. Integrin_B_tail. 1 hit.
[Graphical view]
SUPFAMiSSF103575. SSF103575. 1 hit.
SSF53300. SSF53300. 1 hit.
SSF69179. SSF69179. 1 hit.
SSF69687. SSF69687. 1 hit.
PROSITEiPS00243. INTEGRIN_BETA. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O96444-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLVVVLIVA CLGTLAQGNE INPCLSADAQ KSCASCIATS KECAWCVSVS
60 70 80 90 100
YEQENRLRCD THENHLRGLY CDPGDIQFPT DEVEKLKNQD VGDGDNPEDA
110 120 130 140 150
VQVQPQKVRI KIRPNKPVEV KLTFRQAENY PVDLYYFMDL SNSMEDDKEK
160 170 180 190 200
LALLGNKIAE QMSAITKNFR LGFGSFVDKV VSPYVSTVPQ KLKMPCKTYN
210 220 230 240 250
GEPCEAPYGF KNQLSLDLET TKFSQKVKEA RVSGNLDAPE GGFDAIMQAV
260 270 280 290 300
ACEDEIGWRP ISRRMLVFST DAGFHHAGDG KLGGIVTPND GQCHLKNNLY
310 320 330 340 350
SESSNLDYPS VSQIANKIKE KSVSVIFAVT DLQFDIYEKL SKYIESSTTG
360 370 380 390 400
RLANDSSNIV TLIEDNYKKI TSKVTLKADG LGENITVDFF SRCFGGEEIK
410 420 430 440 450
TNECGSLKIG QSVEFRAEVM LTACPKDRKK WLKEFSIRPL GYQEKLTVEL
460 470 480 490 500
EMICECQCEN AENEELNSDK CSNGNGTFEC GKCSCHPGRY GKFCECKADD
510 520 530 540 550
LTSKDSIKQC TAPNATLPCS GRGSCVCGEC LCNTRSSDSA QTFSGPYCEC
560 570 580 590 600
DDYSCNQFNE QICGGPERGK CNCGKCECKL GYNGTACECE LSMEKCTTDK
610 620 630 640 650
GLVCNGHGNC TCGKCVCENQ YTGFKCEQCP ACPDKCLEYT PCVQCKAFKF
660 670 680 690 700
GKLIQERCLR ECKMEIFFHD KIREGHGIQL CPIKDDDECW AYYTYEYDRN
710 720 730 740 750
GKVVIKAQIT KVCPDQLNVL AIVGGVVGGI VAVGLFLLLL WKLLTFIHDT
760 770 780
REFAKFEKER QNAKWDTGEN PIYKQATSTF KNPTYGSQ
Length:788
Mass (Da):87,633
Last modified:May 1, 1999 - v1
Checksum:i3FE3DFAFE0848163
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF060203 mRNA. Translation: AAC67503.1.
RefSeqiNP_001298213.1. NM_001311284.1.

Genome annotation databases

GeneIDi106062969.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF060203 mRNA. Translation: AAC67503.1.
RefSeqiNP_001298213.1. NM_001311284.1.

3D structure databases

ProteinModelPortaliO96444.
SMRiO96444. Positions 742-785.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi106062969.

Family and domain databases

Gene3Di3.40.50.410. 1 hit.
InterProiIPR013111. EGF_extracell.
IPR015812. Integrin_bsu.
IPR014836. Integrin_bsu_cyt_dom.
IPR002369. Integrin_bsu_N.
IPR012896. Integrin_bsu_tail.
IPR032695. Integrin_dom.
IPR016201. Plexin-like_fold.
IPR002035. VWF_A.
[Graphical view]
PANTHERiPTHR10082. PTHR10082. 1 hit.
PfamiPF07974. EGF_2. 1 hit.
PF08725. Integrin_b_cyt. 1 hit.
PF07965. Integrin_B_tail. 1 hit.
PF00362. Integrin_beta. 1 hit.
[Graphical view]
PIRSFiPIRSF002512. Integrin_B. 1 hit.
PRINTSiPR01186. INTEGRINB.
SMARTiSM00187. INB. 1 hit.
SM01241. Integrin_b_cyt. 1 hit.
SM01242. Integrin_B_tail. 1 hit.
[Graphical view]
SUPFAMiSSF103575. SSF103575. 1 hit.
SSF53300. SSF53300. 1 hit.
SSF69179. SSF69179. 1 hit.
SSF69687. SSF69687. 1 hit.
PROSITEiPS00243. INTEGRIN_BETA. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning of a beta integrin subunit cDNA from an embryonic cell line derived from the freshwater mollusc, Biomphalaria glabrata."
    Davids B.J., Wu X.J., Yoshino T.P.
    Gene 228:213-223(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO96444_BIOGL
AccessioniPrimary (citable) accession number: O96444
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: June 8, 2016
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.