O96432 (CBK_TRIVA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Carbamate kinase
EC=2.7.2.2

Gene names

Name:

CBK

Organism

Trichomonas vaginalis

Taxonomic identifier

5722 [NCBI]

Taxonomic lineage

Eukaryota › Parabasalia › Trichomonadida › Trichomonadidae › Trichomonas

Protein attributes

Sequence length	314 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	ATP + NH3 + CO2 = ADP + carbamoyl phosphate.
Pathway	Metabolic intermediate metabolism; carbamoyl phosphate degradation; CO(2) and NH(3) from carbamoyl phosphate: step 1/1.
Subunit structure	Homodimer.
Sequence similarities	Belongs to the carbamate kinase family.

Ontologies

Keywords
Biological process	Arginine metabolism
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Gene Ontology (GO)
Biological process	arginine metabolic process Inferred from electronic annotation. Source: UniProtKB-KW cellular amino acid biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW carbamate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 314	314	Carbamate kinase		PRO_0000185153

Sequences

	Sequence		Length	Mass (Da)
	O96432 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 4E00507941CF340C	FASTA	314	33,927
	10 20 30 40 50 60 MRIVVALGGN ALLQRGMKGT FQDQQAACRL AMSQIVKIVK DGNELVMTHG NGPQCGAIFL 70 80 90 100 110 120 QNVAGEQEKV PAMPLHVCGA ETQGFLGELL QQELDGALRA EGIKKNVVSI VTQSFVDPKD 130 140 150 160 170 180 PAFQNPTKPI GPFYSKEEAE FLRNERGYNM VEDAGRGYRM IVPSPVPQKF VEKEAIKTLV 190 200 210 220 230 240 NSGFIVVCSG GGGIPVILDE QENRIEGVDA VIDKDLGASV LAAATNADAF MILTDVPEAL 250 260 270 280 290 300 LNYRKENETA IRQATVAEME KYIEEGHFIK GSMLPKVQAC LRFVKSTGKP ALITALDCAL 310 QALKGERGTK IVPN

References

[1]	"Trichomonas vaginalis: characterization, expression, and phylogenetic analysis of a carbamate kinase gene sequence." Minotto L., Edwards M.R., Bagnara A.S. Exp. Parasitol. 95:54-62(2000) [PubMed: 10864518] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], MASS SPECTROMETRY, CHARACTERIZATION. Strain: WAA38.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF050082 Genomic DNA. Translation: AAD02507.1.
3D structure databases
ProteinModelPortal	O96432.
SMR	O96432. Positions 2-313.
ModBase	Search...
Protein-protein interaction databases
STRING	O96432.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Enzyme and pathway databases
BRENDA	2.7.2.2. 6459.
Family and domain databases
InterPro	IPR001048. Asp/Glu/Uridylate_kinase. IPR003964. Bac_carb_kinase. [Graphical view]
Gene3D	G3DSA:3.40.1160.10. Aa_kinase. 1 hit.
Pfam	PF00696. AA_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000723. Carbamate_kin. 1 hit.
PRINTS	PR01469. CARBMTKINASE.
SUPFAM	SSF53633. Aa_kinase. 1 hit.
TIGRFAMs	TIGR00746. ArcC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CBK_TRIVA

Accession

Primary (citable) accession number: O96432

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 23, 2003
Last sequence update:	May 1, 1999
Last modified:	July 27, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)