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Protein

Replication factor C subunit 1

Gene

PF3D7_0219600

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

  • DNA repair Source: InterPro
  • DNA replication Source: GeneDB

Keywordsi

Biological processDNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-PFA-110320. Translesion Synthesis by POLH.
R-PFA-174411. Polymerase switching on the C-strand of the telomere.
R-PFA-69091. Polymerase switching.

Names & Taxonomyi

Protein namesi
Recommended name:
Replication factor C subunit 1UniRule annotation
Gene namesi
ORF Names:PF3D7_0219600Imported, PFB0895cImported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0219600.

Subcellular locationi

  • Nucleus UniRule annotation

GO - Cellular componenti

  • DNA replication factor C complex Source: GeneDB
  • nucleus Source: UniProtKB-SubCell

Keywords - Cellular componenti

NucleusUniRule annotation

Structurei

3D structure databases

SMRiO96271.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini213 – 311BRCTInterPro annotationAdd BLAST99

Sequence similaritiesi

Belongs to the activator 1 large subunit family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000284296.
InParanoidiO96271.
KOiK10754.
OMAiPKMKPFD.

Family and domain databases

CDDicd00027. BRCT. 1 hit.
Gene3Di3.40.50.10190. 1 hit.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR001357. BRCT_dom.
IPR036420. BRCT_dom_sf.
IPR008921. DNA_pol3_clamp-load_cplx_C.
IPR013725. DNA_replication_fac_RFC1_C.
IPR027417. P-loop_NTPase.
IPR012178. RFC1.
PfamiView protein in Pfam
PF00004. AAA. 1 hit.
PF00533. BRCT. 1 hit.
PF08519. RFC1. 1 hit.
PIRSFiPIRSF036578. RFC1. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SM00292. BRCT. 1 hit.
SUPFAMiSSF48019. SSF48019. 1 hit.
SSF52113. SSF52113. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS50172. BRCT. 1 hit.

Sequencei

Sequence statusi: Complete.

O96271-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSKDKNLFS DDESDDGRKK KRLKKVSSSL FHDDDDDNFI SNKKVEKSKS
60 70 80 90 100
KKKSDAIYID DNESNNNNNY NNTNKSSNRK SLENKSSKTS PKFYDITSFF
110 120 130 140 150
KPSSKKLEDN NTMKKSNSKE DEKLVVNNLN DYFNILQNDN KVTKEDTKSN
160 170 180 190 200
NVSPKNEINK SNVKRERESE QYEISSENDT VSSKKNVLIS PAKKQKTQNN
210 220 230 240 250
NNEDLQKFDY LPFHNQKFVI TGVFKNFTRD ELQSKIKEHG GSVMTAVSTK
260 270 280 290 300
TNYLVHGEYL EDGRLFNEGR KYTKAFELQQ QNKSNIKILN EEELLKLLPQ
310 320 330 340 350
TDQTQENDKT YASDTIKTEN KDKNYNYEKK DKNYNYEKKD THNTQNEILN
360 370 380 390 400
QLWVEKYRPK NLNELVGNNQ NVIKLQNWLA SWEDVCIKGI KKPAQKTFRG
410 420 430 440 450
IFENVNARCA LLSGPAGIGK TTTAKIVSEA SGYNVIEFNA SDERNKAAVE
460 470 480 490 500
KISEMATGGY SIMSLNNRKL TKTCIIMDEV DGMSSGDKGG STAILKLIEK
510 520 530 540 550
TKCPIICICN DRQNNKMRTL ANKCYDLKFS MPQKNSVVKR LLEICKKEGI
560 570 580 590 600
MMEPNALELL WESTCGDIRQ MLNTLQLLSK TYTRIQFLDL KKELNNSNKN
610 620 630 640 650
IQSLANPFEI TLKLLNFNES SKLNIREIMD LFFVDYELIP YFISENYTNV
660 670 680 690 700
FNETDKSSAS LNKWNVFSQI AHDLSLADKI KYNMKSNMDF ALLPHFAILS
710 720 730 740 750
CVCPVMRIKI LKSFMSGRVN FPTAFGKIST FNKNKRLLNE LCFNLSYKLN
760 770 780 790 800
VCPKYMVTSG FLNYIYFKIM TPLHKADVNQ AIQIMEEYSI TREMVTENLP
810 820 830 840 850
CLRLPNQENL YDKLDTKLKS SFTRLYNSSH VIKIDPNSMK KGLKSSEKKT
860 870 880 890 900
TFKLNEFESD EDIDELSESK EDKDDDVLIK TKIDRKGTLK TKPSTKVKSM

KKAK
Length:904
Mass (Da):104,185
Last modified:May 1, 1999 - v1
Checksum:i5B2982CCAAB13F0B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001362 Genomic DNA. Translation: AAC71968.1.
LN999943 Genomic DNA. Translation: CZT98208.1.
PIRiD71603.
RefSeqiXP_001349697.1. XM_001349661.1.

Genome annotation databases

EnsemblProtistsiCZT98208; CZT98208; PF3D7_0219600.
GeneDBiPF3D7_0219600.1:pep.
GeneIDi812779.
KEGGipfa:PFB0895c.

Similar proteinsi

Entry informationi

Entry nameiO96271_PLAF7
AccessioniPrimary (citable) accession number: O96271
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: November 22, 2017
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported