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Protein
Submitted name:

DEAD/DEAH box helicase, putative

Gene

PF3D7_0216000

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  • ATP binding Source: InterPro
  • DNA helicase activity Source: GeneDB

GO - Biological processi

  • chromatin remodeling Source: GeneDB

Keywordsi

Molecular functionHelicaseImported, Hydrolase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
DEAD/DEAH box helicase, putativeImported (EC:3.6.4.13Imported)
Gene namesi
ORF Names:PF3D7_0216000Imported, PFB0730wImported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0216000.

Subcellular locationi

GO - Cellular componenti

  • SWI/SNF complex Source: GeneDB

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini896 – 1061Helicase ATP-bindingInterPro annotationAdd BLAST166
Domaini1197 – 1505Helicase C-terminalInterPro annotationAdd BLAST309

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili127 – 250Sequence analysisAdd BLAST124
Coiled coili261 – 281Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

InParanoidiO96239.
KOiK11647.
OMAiGNENMNM.

Family and domain databases

CDDicd00079. HELICc. 2 hits.
InterProiView protein in InterPro
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000330. SNF2_N.
PfamiView protein in Pfam
PF00271. Helicase_C. 2 hits.
PF00176. SNF2_N. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 3 hits.
PROSITEiView protein in PROSITE
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.

Sequencei

Sequence statusi: Complete.

O96239-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MINSDNKCMN DNKESIPKEY KTQDMIEGEK ERKNKIIKEY IKNMNEEDFL
60 70 80 90 100
YLSEHLKIRI DNEIFMSQEL NDYINKHIDI ICELHFKNFK RPKTHMKKVF
110 120 130 140 150
IDLTLKLKYL RHLEYLKRKK KKDKENKSKS KKEKNNKNEK DDEMENKKEK
160 170 180 190 200
NNKNEKDDEM ENKKEKNNKN EKDDEMENKK EKNNKNEKDD EMENKKEKNN
210 220 230 240 250
KNEKDDEMEN KKEKNNKNEK DDEMENKKEK NNKNEKDDEI KENMDKVMEN
260 270 280 290 300
QLNQSNILYN KDRIRKNRNN LKDEKDVSNK NILDDNKDIV EFKLQDISSG
310 320 330 340 350
YSETSCKSTN SIENGNSSST SSCDDDSSFL FSCSSDCDEE TSDEEILSTI
360 370 380 390 400
HFDEKEMSTL KSLEKAKNVY FAYINKKFKK YNILDHFNMN FLERLNYYFS
410 420 430 440 450
KLYYQNNNLK QTNEYQNRIK EFLSNEENVK KIELNQSKLR SDILNSMFGF
460 470 480 490 500
HIINETHPMK LPIKNMNNLS YQNTKVDNIY AYKSNTNKCR VHTKLNQLYE
510 520 530 540 550
TNDNIRNMNY YKTIEYMNSE NNINNMNILN EWTNFMDQNI NIESISPEQH
560 570 580 590 600
KKGNRKKKIN TKKLYHHDNY NNNNNNNNND NNNDNNNDNN NDNNNDNNND
610 620 630 640 650
NNNNINCIYG EHHNVKHKKR KSTSKSKHIF RSNEVSIHFN DDIKKIEHVA
660 670 680 690 700
KKELQEYIKQ IHNKSKIHNN ISSLKQYMLI SNWKELTKHN NYMTLLSEEK
710 720 730 740 750
KRNSKILANL CYNQMKAIDQ KRKIILEKEE RERMKLLKDN DIEAYMKLIK
760 770 780 790 800
TAKNKRLQEL LDVTEQFLNN MSKCVLYQKK EAYQESSEQN FHGLINHKNE
810 820 830 840 850
DNEKCHKNYN SKDNNNILQS VHNLTTHGQQ NGYNNKKGYD TMYEHNENNT
860 870 880 890 900
KICNYKNARE NYYNISHVVK EKVKQPSILI GGELMKYQLE GLEWLVSLYN
910 920 930 940 950
NNLHGILADE MGLGKTIQTI SLFAYLKEFK NNINVKNLII VPLSTLPNWI
960 970 980 990 1000
SEFNRWCPSL NVITYRGNKL ERKHIAKKLL EQTFDICITT FDLVIKEKSF
1010 1020 1030 1040 1050
LMKISWNYIV VDEGHRMKNN KSRFHVFLSE FKSKYRILLT GTPLQNNLSE
1060 1070 1080 1090 1100
LWSLLNFLLP KIFSSCVDFE KWFVKSLHNE KDVYEHITEE EQLLIINRLH
1110 1120 1130 1140 1150
SVLLPFMLRR VKKDVLKSLP KKYEYNIHIE LSLYQKILYK QIQTKGFKQV
1160 1170 1180 1190 1200
NHNGSITTKI FQNIVMQLRK IVNHPYLFLY DYNIDENIIK CSGKFEVLDR
1210 1220 1230 1240 1250
MLPKLLKFKH KVLIFSQMTK LMNILCDYLE FRGYKYHRLD GNIGLQERKK
1260 1270 1280 1290 1300
IIDQFNNNVE YKKDEGKQPN CEMPGNENMN MSGNENMNMS VNENMNMSVN
1310 1320 1330 1340 1350
ENMNMSGNEN MNMSGNENMN MSGNENMNMS GNENMNMSGN ENMNMSGNEN
1360 1370 1380 1390 1400
MNMSGNENIK MISSQNEKDT SSQSVKISEL KKEEINDFQI MDDKNVNGGN
1410 1420 1430 1440 1450
QDAMIFILST RSGSLGLNLQ TADTVIIFDS DFNPHQDIQA MCRCHRIGQK
1460 1470 1480 1490 1500
NVVKVFRFIT LSGVEELVFK KAQHKLSIND KVIQAGLFNK IYNDEDRQNK
1510 1520 1530 1540 1550
LKDIIQRNQK NDMTTHPTNP LLLNYYMKRN EEELEYFLDF DKRYFGEQYF
1560 1570 1580 1590 1600
SLLNTLNVEN VDSGQFTYMS EDEKEENETY LSSIIKKEKK EEEGEDDEEN
1610 1620 1630 1640 1650
QRDRNKEEDQ DEDKDDDKDK DKDKDKEEEE EKKRKHILNN NNNNGIQNGS
1660 1670 1680 1690 1700
SINEGVKEKI LDEYCNNNTK CVKVSNERLI FKRKHDTDDL QCEDEKIKEN
1710 1720 1730 1740 1750
EECDVDNIIQ NKNNKRLKME CQKDDKDDDI NSNIHMDEKK KIYMSSEKDD
1760 1770 1780 1790 1800
TTKEYSDTHD PYINDKMQVK DEEDYYGFIL KEENQNDIEK ILIKSNKLIN
1810 1820 1830 1840 1850
KDELPAYLFY DDTNDSPDKI NLKRSRKVIN INLMQEEKLT EKQFLKLIDS
1860 1870 1880 1890 1900
SSPNLLSSVE KDLGRNKKDI VKSDMEHNND ITTLEEVKDR EEIKEEHLET
1910 1920 1930 1940 1950
TKNISSLNIN DLEINKTLTN ENVHSTKKSP YNMRSSKRRS DTSSTYMETS
1960 1970 1980 1990
IKKRNDKDIH ICLKKGKKRN NSMEHTKQEC HVDDENKKRV KKRKSSQ
Length:1,997
Mass (Da):237,127
Last modified:May 1, 1999 - v1
Checksum:i528C98B6237D4AE3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001362 Genomic DNA. Translation: AAC71935.1.
LN999943 Genomic DNA. Translation: CZT98173.1.
PIRiF71607.
RefSeqiXP_001349665.1. XM_001349629.1.

Genome annotation databases

EnsemblProtistsiCZT98173; CZT98173; PF3D7_0216000.
GeneDBiPF3D7_0216000.1:pep.
GeneIDi812747.
KEGGipfa:PFB0730w.

Similar proteinsi

Entry informationi

Entry nameiO96239_PLAF7
AccessioniPrimary (citable) accession number: O96239
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: December 20, 2017
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported