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Protein
Submitted name:

5'-3' exonuclease, N-terminal resolvase-like domain, putative

Gene

PF3D7_0203900

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  • 5'-3' exonuclease activity Source: GeneDB
  • DNA binding Source: GeneDB
  • DNA-directed DNA polymerase activity Source: GO_Central

GO - Biological processi

Keywordsi

Molecular functionExonucleaseImported, Hydrolase, Nuclease

Names & Taxonomyi

Protein namesi
Submitted name:
5'-3' exonuclease, N-terminal resolvase-like domain, putativeImported (EC:3.1.16.1Imported)
Gene namesi
ORF Names:PF3D7_0203900Imported, PFB0180wImported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0203900.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501013312922 – 577Sequence analysisAdd BLAST556

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini106 – 54953EXOcInterPro annotationAdd BLAST444

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili75 – 95Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

InParanoidiO96139.

Family and domain databases

CDDicd09898. H3TH_53EXO. 1 hit.
Gene3Di3.40.50.1010. 1 hit.
InterProiView protein in InterPro
IPR020046. 5-3_exonucl_a-hlix_arch_N.
IPR036279. 5-3_exonuclease_C_sf.
IPR002421. 5-3_exonuclease_N.
IPR020045. DNA_polI_H3TH.
IPR008918. HhH2.
IPR029060. PIN-like_dom_sf.
PfamiView protein in Pfam
PF01367. 5_3_exonuc. 1 hit.
PF02739. 5_3_exonuc_N. 1 hit.
SMARTiView protein in SMART
SM00475. 53EXOc. 1 hit.
SM00279. HhH2. 1 hit.
SUPFAMiSSF47807. SSF47807. 1 hit.
SSF88723. SSF88723. 1 hit.

Sequencei

Sequence statusi: Complete.

O96139-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKSIYIILL CVKYFLIYSK AYKKKNNNDV INNIQRAKND LFFIKPSVKL
60 70 80 90 100
NLCSSKFIHR IKSVNKRYVE KNEYIQQIDN DIEEKKKKKK TTSKRNNKSS
110 120 130 140 150
NQINDDYETF LIVDGSSILF KNFFGMPFLK NDNDVNLSTI YGFIQSLNKI
160 170 180 190 200
YNLFLPTYIA IIFDSKTSNN DKKKIYANYK IFRRKNPDEL YEQLKIVSNF
210 220 230 240 250
CDTIGIKTIS STNIESDDYI ARIVDNISNT LKEKKQKDFS FVNNHQEKEP
260 270 280 290 300
PPMYTYMKNN VYDNAGSIGT NKIFDKEPNH INGNINGNVN DHTNGNVNDH
310 320 330 340 350
INGNINDHIN GNINDHINDH TNDHTNDHTN DHTNDHTNDH TNDHLNDYEY
360 370 380 390 400
YEYYNTNDDD HYNINDDDHY HINDDAYNNF YDNIYAEENV SCHENVATNN
410 420 430 440 450
IDKKKKFRVI VVSSDKDLLQ LLEYNNETYN MDISICQPNK KYRLVNSHLF
460 470 480 490 500
YEEHEILPSQ YSDYLILTGD KTDGISGVPY IGDKTSKCLL KEYHNIENIL
510 520 530 540 550
KNLHKLPSKL HHIFLNNIEN INTFRKLIKL KCETNESLVF DDYKQKRIKN
560 570
FEQFRNFADK YSLHKLLKKS VIVNYHD
Length:577
Mass (Da):68,024
Last modified:March 1, 2003 - v2
Checksum:iB410F8AAF92834A0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001362 Genomic DNA. Translation: AAC71825.2.
LN999943 Genomic DNA. Translation: CZT98051.1.
PIRiC71621.
RefSeqiXP_001349551.1. XM_001349515.1.

Genome annotation databases

EnsemblProtistsiCZT98051; CZT98051; PF3D7_0203900.
GeneDBiPF3D7_0203900.1:pep.
GeneIDi812633.
KEGGipfa:PFB0180w.

Similar proteinsi

Entry informationi

Entry nameiO96139_PLAF7
AccessioniPrimary (citable) accession number: O96139
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: March 1, 2003
Last modified: December 20, 2017
This is version 102 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported