Unreviewed, UniProtKB/TrEMBL O96046 (O96046_DROME)

Names and origin

Protein names

Submitted name:
    Cortactin EMBL BAA34397.1

Gene names

Name:	Cortactin FlyBase FBgn0025865
Synonyms:	DCortactin EMBL BAA34397.1
ORF Names:	CG3637 FlyBase FBgn0025865

Organism

Drosophila melanogaster (Fruit fly) EMBL BAA34397.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	559 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Contains 1 SH3 domain. RuleBase RU003338V3

Ontologies

Keywords
Domain	SH3 domain RuleBase RU003338V3
Gene Ontology (GO)
Biological process	border follicle cell migration Inferred from mutant phenotype. Source: FlyBase ovarian ring canal formation Inferred from mutant phenotype. Source: FlyBase regulation of cell shape Inferred from mutant phenotype. Source: FlyBase
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O96046-1 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: DD78CE63948F09CA	FASTA	559	61,075
	10 20 30 40 50 60 MWKASAGHQI QATSAASAED DDWETDPDFV NDVSEQEQRW GSKTIDGSGR TAGTIDMDKL 70 80 90 100 110 120 REETEQADLD KKKQLLKDQN AGYGYGGKFG VEKDRMDKSA VGHDYQGKVG KHASQKDYSD 130 140 150 160 170 180 GFGGKFGVQE DRKDKSAVGW DHVEKVEKHA SQKDYATGFG GKFGVQSDRV DKSAVGWDHI 190 200 210 220 230 240 EKVEKHESQK DYSKGFGGKF GVQEDRKDKS AVGWDHKEAP QKHASQVDHK VKPVIEGAKP 250 260 270 280 290 300 SNLRAKFENL AKNSEEESRK RAEEQKRLRE AKDKRDREEA AKKTVAENTP RTSTEAPPPK 310 320 330 340 350 360 GSRAAIQTGR TGGIGNAISA FNQMQSPVSE TPPARKEPII IPKAQPVKIE VEAKEEPTAS 370 380 390 400 410 420 TTSAAVAPTP TVVPAREPET APVAKATAPP PDVVPQIEVE TVDTPPRSEP QSPVYVPTPQ 430 440 450 460 470 480 PEVLAQVQVQ PEPQPQADPE PVVEEEPLYQ NQAEIKAASP LPPTNGTVSE AVAPSGTATV 490 500 510 520 530 540 PEEAIYANSD NLADYLEDTG IHAIALYDYQ AADDDEISFD PDDVITHIEK IDDGWWRGLC 550 KNRYGLFPAN YVQVVGQNS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cortactin associates with the cell-cell junction protein ZO-1 in both Drosophila and mouse." Katsube T., Takahisa M., Ueda R., Hashimoto N., Kobayashi M., Togashi S. J. Biol. Chem. 273:29672-29677(1998) [PubMed: 9792678] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Canton-S EMBL BAA34397.1.
[2]	"An integrated chemical, mass spectrometric and computational strategy for (quantitative) phosphoproteomics: application to Drosophila melanogaster Kc167 cells." Bodenmiller B., Mueller L.N., Pedrioli P.G.A., Pflieger D., Juenger M.A., Eng J.K., Aebersold R., Tao W.A. Mol. Biosyst. 3:275-286(2007) [PubMed: 17372656] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.
[3]	"Characterization of the gene encoding Drosophila Cortactin." Takanori K., Hashimoto N., Sasaki Y., Yamashita A., Takahisa M., Ueda R., Togashi S. Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Canton-S EMBL BAB01490.1.
[4]	Katsube T., Togashi S. Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Canton-S EMBL BAB01490.1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB009998 mRNA. Translation: BAA34397.1. AB030177 Genomic DNA. Translation: BAB01490.1.
3D structure databases
HSSP	HSSP built from PDB template 1JO8 based on UniProtKB P15891.
SMR	O96046. Positions 498-554.
ModBase	Search...
Protein-protein interaction databases
IntAct	O96046. 1 interaction.
Proteomic databases
PRIDE	O96046.
Genome annotation databases
Ensembl	FBgn0025865. Drosophila melanogaster. [Contig view]
Organism-specific databases
FlyBase	FBgn0025865. Cortactin.
Phylogenomic databases
HOGENOM	O96046.
Gene expression databases
ArrayExpress	O96046.
Family and domain databases
InterPro	IPR003134. Hs1_Cortactin. IPR000108. Neu_cyt_fact_2. IPR001452. SH3_domain. [Graphical view]
Pfam	PF02218. HS1_rep. 4 hits. PF00018. SH3_1. 1 hit. [Graphical view]
PRINTS	PR00499. P67PHOX.
ProDom	PD000066. SH3. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00326. SH3. 1 hit. [Graphical view]
PROSITE	PS51090. CORTACTIN. 4 hits. PS50002. SH3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O96046_DROME

Accession

Primary (citable) accession number: O96046

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 1999
Last sequence update:	May 1, 1999
Last modified:	June 16, 2009
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)