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Protein

Putative transmembrane protein CXorf1

Gene

CXorf1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein uncertaini

Functioni

Caution

Product of a dubious CDS prediction. Most probably an erroneously predicted open reading frame in the 3' UTR of the SLITRK2 gene.Curated

Names & Taxonomyi

Protein namesi
Recommended name:
Putative transmembrane protein CXorf1Curated
Gene namesi
Name:CXorf11 Publication
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

EuPathDBiHostDB:ENSG00000221870.2
MIMi300565 gene
neXtProtiNX_O96002

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei23 – 43HelicalSequence analysisAdd BLAST21
Transmembranei58 – 78HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000221870
PharmGKBiPA27059

Polymorphism and mutation databases

BioMutaiTMEM257

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000797291 – 111Putative transmembrane protein CXorf1Add BLAST111

Proteomic databases

PaxDbiO96002
PRIDEiO96002

PTM databases

iPTMnetiO96002
PhosphoSitePlusiO96002

Expressioni

Tissue specificityi

Brain. In the hippocampus it is mainly localized in the granular-cell layer of the dentate gyrus and in the CA2-CA3 subfields of Ammon's horn.1 Publication

Gene expression databases

BgeeiENSG00000221870
CleanExiHS_CXorf1
GenevisibleiO96002 HS

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000386149

Structurei

3D structure databases

ProteinModelPortaliO96002
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410KCJN Eukaryota
ENOG4110NW9 LUCA
GeneTreeiENSGT00510000055407
HOGENOMiHOG000112096
InParanoidiO96002
OMAiTIFYFRI
OrthoDBiEOG091G0WPJ
PhylomeDBiO96002

Sequencei

Sequence statusi: Complete.

O96002-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYSRLFYLKS SYIIYFEPLF SNAIINILSF INSLASPLTI FCFALSAQAL
60 70 80 90 100
STIFYFRIFI FIFHSWILLF HFYFTCSFKT YEHQHSKMVP AYRMQSPRAL
110
PRTYLYVWPY K
Length:111
Mass (Da):13,452
Last modified:May 1, 1999 - v1
Checksum:i5EFA883C1329A522
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_03376636S → A. Corresponds to variant dbSNP:rs3752359Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y10607 Genomic DNA Translation: CAA71614.1
Y08902 mRNA Translation: CAA70110.1
AL109653 Genomic DNA No translation available.
BC113600 mRNA Translation: AAI13601.1
BC113604 mRNA Translation: AAI13605.1
RefSeqiNP_004700.1, NM_004709.2
UniGeneiHs.106688
Hs.320368

Genome annotation databases

UCSCiuc004fch.4 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiCX001_HUMAN
AccessioniPrimary (citable) accession number: O96002
Secondary accession number(s): Q14CW0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: May 23, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health