##gff-version 3
O95992	UniProtKB	Chain	1	272	.	.	.	ID=PRO_0000226801;Note=Cholesterol 25-hydroxylase	
O95992	UniProtKB	Transmembrane	38	58	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
O95992	UniProtKB	Transmembrane	84	104	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
O95992	UniProtKB	Transmembrane	121	141	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
O95992	UniProtKB	Domain	129	263	.	.	.	Note=Fatty acid hydroxylase;Ontology_term=ECO:0000255;evidence=ECO:0000255	
O95992	UniProtKB	Motif	142	146	.	.	.	Note=Histidine box-1	
O95992	UniProtKB	Motif	157	161	.	.	.	Note=Histidine box-2	
O95992	UniProtKB	Motif	238	244	.	.	.	Note=Histidine box-3	
O95992	UniProtKB	Glycosylation	5	5	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
O95992	UniProtKB	Glycosylation	163	163	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
O95992	UniProtKB	Glycosylation	189	189	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
O95992	UniProtKB	Natural variant	133	133	.	.	.	ID=VAR_048899;Note=L->P;Dbxref=dbSNP:rs17117295	
O95992	UniProtKB	Mutagenesis	242	243	.	.	.	Note=Loss of cholesterol 25-hydroxylase activity. Loss of inhibition of infection by SARS-COV-2. HH->QQ;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:33239446;Dbxref=PMID:33239446