##gff-version 3
O95935	UniProtKB	Chain	1	607	.	.	.	ID=PRO_0000184446;Note=T-box transcription factor TBX18	
O95935	UniProtKB	DNA binding	143	330	.	.	.	Note=T-box;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00201	
O95935	UniProtKB	Region	30	141	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
O95935	UniProtKB	Motif	18	28	.	.	.	Note=Engrailed homology 1 repressor;Ontology_term=ECO:0000305;evidence=ECO:0000305	
O95935	UniProtKB	Motif	36	40	.	.	.	Note=Nuclear localization signal;Ontology_term=ECO:0000305;evidence=ECO:0000305	
O95935	UniProtKB	Compositional bias	32	46	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
O95935	UniProtKB	Natural variant	48	48	.	.	.	ID=VAR_052263;Note=G->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15489334;Dbxref=dbSNP:rs172562,PMID:15489334	
O95935	UniProtKB	Natural variant	163	163	.	.	.	ID=VAR_074629;Note=In CAKUT2%3B results in decreased transcriptional repression through a dominant negative effect%3B does not affect nuclear localization%3B does not bind DNA%3B no effect on interaction with SIX1%3B no effect on interaction with TLE3. K->E;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:26235987;Dbxref=dbSNP:rs797045022,PMID:26235987	
O95935	UniProtKB	Natural variant	164	164	.	.	.	ID=VAR_074630;Note=A->T;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:26235987;Dbxref=PMID:26235987	
O95935	UniProtKB	Natural variant	524	524	.	.	.	ID=VAR_074631;Note=In CAKUT2%3B results in decreased transcriptional repression through a dominant negative effect%3B does not affect nuclear localization%3B no effect on DNA binding%3B no effect on interaction with SIX1%3B no effect on interaction with TLE3. H->Y;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:26235987;Dbxref=dbSNP:rs760905589,PMID:26235987	
O95935	UniProtKB	Natural variant	526	526	.	.	.	ID=VAR_074632;Note=P->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:26235987;Dbxref=PMID:26235987