O95873 (CF047_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein C6orf47

Alternative name(s):
Protein G4

Gene names

Name:	C6orf47
Synonyms:	G4

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	294 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 294	294	Uncharacterized protein C6orf47		PRO_0000089504
Natural variations
	Natural variant	68	1	G → R. Ref.1 Ref.2 Ref.3 Ref.4 Ref.5 Corresponds to variant rs3130617 [ dbSNP | Ensembl ].		VAR_022911
	Natural variant	92	1	K → N. Corresponds to variant rs2242655 [ dbSNP | Ensembl ].		VAR_056797

Sequences

	Sequence		Length	Mass (Da)
	O95873 [UniParc]. Last modified January 11, 2011. Version 2. Checksum: 59ACE578FB60284D	FASTA	294	31,710
	10 20 30 40 50 60 MFLRRLGGWL PRPWGRRKPM RPDPPYPEPR RVDSSSENSG SDWDSAPETM EDVGHPKTKD 70 80 90 100 110 120 SGALRVSGAA SEPSKEEPQV EQLGSKRMDS LKWDQPISST QESGRLEAGG ASPKLRWDHV 130 140 150 160 170 180 DSGGTRRPGV SPEGGLSVPG PGAPLEKPGR REKLLGWLRG EPGAPSRYLG GPEECLQIST 190 200 210 220 230 240 NLTLHLLELL ASALLALCSR PLRAALDTLG LRGPLGLWLH GLLSFLAALH GLHAVLSLLT 250 260 270 280 290 AHPLHFACLF GLLQALVLAV SLREPNGDEA ATDWESEGLE REGEEQRGDP GKGL

References

[1]	"Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse." Xie T., Rowen L., Aguado B., Ahearn M.E., Madan A., Qin S., Campbell R.D., Hood L. Genome Res. 13:2621-2636(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANT ARG-68.
[2]	"Homo sapiens 2,229,817bp genomic DNA of 6p21.3 HLA class I region." Shiina S., Tamiya G., Oka A., Inoko H. Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANT ARG-68.
[3]	"The DNA sequence and analysis of human chromosome 6." Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D. , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S. Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANT ARG-68.
[4]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANT ARG-68.
[5]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ARG-68. Tissue: Eye.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF129756 Genomic DNA. Translation: AAD18083.1. BA000025 Genomic DNA. Translation: BAB63388.1. AL662801, AL662899 Genomic DNA. Translation: CAI18277.1. AL662899, AL662801 Genomic DNA. Translation: CAI18383.1. AL670886 Genomic DNA. Translation: CAI17791.1. AL805934 Genomic DNA. Translation: CAI18514.1. BX511262 Genomic DNA. Translation: CAM45817.1. CR753842 Genomic DNA. Translation: CAQ06564.1. CR354443 Genomic DNA. Translation: CAQ06994.1. CR759761 Genomic DNA. Translation: CAQ10871.1. CH471081 Genomic DNA. Translation: EAX03465.1. BC012950 mRNA. Translation: AAH12950.1.
IPI	IPI00428484.
RefSeq	NP_067007.3. NM_021184.3.
UniGene	Hs.247323.
3D structure databases
ProteinModelPortal	O95873.
ModBase	Search...
Protein-protein interaction databases
IntAct	O95873. 1 interaction.
STRING	9606.ENSP00000375392.
PTM databases
PhosphoSite	O95873.
Proteomic databases
PaxDb	O95873.
PRIDE	O95873.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000366431; ENSP00000375392; ENSG00000235360. ENST00000366432; ENSP00000375400; ENSG00000203623. ENST00000375911; ENSP00000365076; ENSG00000204439. ENST00000413113; ENSP00000395128; ENSG00000226103. ENST00000418357; ENSP00000398221; ENSG00000226531. ENST00000431256; ENSP00000406870; ENSG00000228435. ENST00000442972; ENSP00000407188; ENSG00000228177.
GeneID	57827.
KEGG	hsa:57827.
UCSC	uc003nvm.1. human.
Organism-specific databases
CTD	57827.
GeneCards	GC06M031641.
H-InvDB	HIX0078436. HIX0166388. HIX0166905. HIX0167163. HIX0167401. HIX0184189.
HGNC	HGNC:19076. C6orf47.
HPA	HPA045281.
neXtProt	NX_O95873.
PharmGKB	PA38785.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG71851.
HOVERGEN	HBG053330.
InParanoid	O95873.
OrthoDB	EOG4K3KXC.
Gene expression databases
Bgee	O95873.
CleanEx	HS_C6orf47.
Genevestigator	O95873.
GermOnline	ENSG00000204439. Homo sapiens.
Family and domain databases
ProtoNet	Search...
Other
ChiTaRS	C6orf47. human.
GenomeRNAi	57827.
NextBio	64811.

Entry information

Entry name

CF047_HUMAN

Accession

Primary (citable) accession number: O95873
Secondary accession number(s): B0UXA1 , B0UZ50, Q5SSS6, Q95IG0

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 19, 2005
Last sequence update:	January 11, 2011
Last modified:	April 3, 2013
This is version 91 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.