Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

O95873 (CF047_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 100. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized protein C6orf47
Alternative name(s):
Protein G4
Gene names
Name:C6orf47
Synonyms:G4
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length294 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

Ontologies

Keywords
   Coding sequence diversityPolymorphism
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from direct assay. Source: HPA

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 294294Uncharacterized protein C6orf47
PRO_0000089504

Natural variations

Natural variant681G → R. Ref.1 Ref.2 Ref.3 Ref.4 Ref.5
Corresponds to variant rs3130617 [ dbSNP | Ensembl ].
VAR_022911
Natural variant921K → N.
Corresponds to variant rs2242655 [ dbSNP | Ensembl ].
VAR_056797

Sequences

Sequence LengthMass (Da)Tools
O95873 [UniParc].

Last modified January 11, 2011. Version 2.
Checksum: 59ACE578FB60284D

FASTA29431,710
        10         20         30         40         50         60 
MFLRRLGGWL PRPWGRRKPM RPDPPYPEPR RVDSSSENSG SDWDSAPETM EDVGHPKTKD 

        70         80         90        100        110        120 
SGALRVSGAA SEPSKEEPQV EQLGSKRMDS LKWDQPISST QESGRLEAGG ASPKLRWDHV 

       130        140        150        160        170        180 
DSGGTRRPGV SPEGGLSVPG PGAPLEKPGR REKLLGWLRG EPGAPSRYLG GPEECLQIST 

       190        200        210        220        230        240 
NLTLHLLELL ASALLALCSR PLRAALDTLG LRGPLGLWLH GLLSFLAALH GLHAVLSLLT 

       250        260        270        280        290 
AHPLHFACLF GLLQALVLAV SLREPNGDEA ATDWESEGLE REGEEQRGDP GKGL 

« Hide

References

[1]"Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse."
Xie T., Rowen L., Aguado B., Ahearn M.E., Madan A., Qin S., Campbell R.D., Hood L.
Genome Res. 13:2621-2636(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANT ARG-68.
[2]"Homo sapiens 2,229,817bp genomic DNA of 6p21.3 HLA class I region."
Shiina S., Tamiya G., Oka A., Inoko H.
Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANT ARG-68.
[3]"The DNA sequence and analysis of human chromosome 6."
Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D. expand/collapse author list , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.
Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANT ARG-68.
[4]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANT ARG-68.
[5]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ARG-68.
Tissue: Eye.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF129756 Genomic DNA. Translation: AAD18083.1.
BA000025 Genomic DNA. Translation: BAB63388.1.
AL662801, AL662899 Genomic DNA. Translation: CAI18277.1.
AL662899, AL662801 Genomic DNA. Translation: CAI18383.1.
AL670886 Genomic DNA. Translation: CAI17791.1.
AL805934 Genomic DNA. Translation: CAI18514.1.
BX511262 Genomic DNA. Translation: CAM45817.1.
CR753842 Genomic DNA. Translation: CAQ06564.1.
CR354443 Genomic DNA. Translation: CAQ06994.1.
CR759761 Genomic DNA. Translation: CAQ10871.1.
CH471081 Genomic DNA. Translation: EAX03465.1.
BC012950 mRNA. Translation: AAH12950.1.
CCDSCCDS34399.1.
RefSeqNP_067007.3. NM_021184.3.
UniGeneHs.247323.

3D structure databases

ProteinModelPortalO95873.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid121786. 3 interactions.
IntActO95873. 1 interaction.
STRING9606.ENSP00000407188.

PTM databases

PhosphoSiteO95873.

Proteomic databases

MaxQBO95873.
PaxDbO95873.
PRIDEO95873.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000366431; ENSP00000375392; ENSG00000235360.
ENST00000366432; ENSP00000375400; ENSG00000203623.
ENST00000375911; ENSP00000365076; ENSG00000204439.
ENST00000413113; ENSP00000395128; ENSG00000226103.
ENST00000418357; ENSP00000398221; ENSG00000226531.
ENST00000431256; ENSP00000406870; ENSG00000228435.
ENST00000442972; ENSP00000407188; ENSG00000228177.
GeneID57827.
KEGGhsa:57827.
UCSCuc003nvm.1. human.

Organism-specific databases

CTD57827.
GeneCardsGC06M031650.
GC06Mj31613.
GC06Mk31608.
GC06Ml31666.
GC06Mm31702.
GC06Mn31616.
GC06Mo31616.
H-InvDBHIX0078436.
HIX0166388.
HIX0166905.
HIX0167163.
HIX0167401.
HIX0184189.
HGNCHGNC:19076. C6orf47.
HPAHPA045281.
HPA053373.
neXtProtNX_O95873.
PharmGKBPA38785.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG71851.
HOVERGENHBG053330.
InParanoidO95873.
OMAAPIVINT.
OrthoDBEOG7P02K8.
PhylomeDBO95873.
TreeFamTF339331.

Gene expression databases

BgeeO95873.
CleanExHS_C6orf47.
GenevestigatorO95873.

Family and domain databases

InterProIPR029073. DUF4661.
[Graphical view]
PANTHERPTHR14307. PTHR14307. 1 hit.
PfamPF15576. DUF4661. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSC6orf47. human.
GenomeRNAi57827.
NextBio64811.

Entry information

Entry nameCF047_HUMAN
AccessionPrimary (citable) accession number: O95873
Secondary accession number(s): B0UXA1 expand/collapse secondary AC list , B0UZ50, Q5SSS6, Q95IG0
Entry history
Integrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: January 11, 2011
Last modified: July 9, 2014
This is version 100 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 6

Human chromosome 6: entries, gene names and cross-references to MIM