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O95600

- KLF8_HUMAN

UniProt

O95600 - KLF8_HUMAN

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Protein
Krueppel-like factor 8
Gene
KLF8, BKLF3, ZNF741
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Transcriptional repressor and activator. Binds to CACCC-boxes promoter elements. Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G1 phase as a downstream target of focal adhesion kinase (FAK).3 Publications

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri274 – 29825C2H2-type 1
Add
BLAST
Zinc fingeri304 – 32825C2H2-type 2
Add
BLAST
Zinc fingeri334 – 35623C2H2-type 3
Add
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Krueppel-like factor 8
Alternative name(s):
Basic krueppel-like factor 3
Zinc finger protein 741
Gene namesi
Name:KLF8
Synonyms:BKLF3, ZNF741
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome X

Organism-specific databases

HGNCiHGNC:6351. KLF8.

Subcellular locationi

Nucleus 1 Publication

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi67 – 671K → R: Abolishes sumoylation. No change in nuclear location. Increases transcriptional activity and cell cycle progression. Abolishes sumoylation; when associated with R-217. 1 Publication
Mutagenesisi217 – 2171K → R: No change in sumoylation. Abolishes sumoylation; when associated with R-67. 1 Publication

Organism-specific databases

PharmGKBiPA30141.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 359359Krueppel-like factor 8
PRO_0000047176Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Cross-linki67 – 67Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)1 Publication

Post-translational modificationi

Sumoylation at Lys-67 represses transcriptional activity and reduces cell cycle progression into the G1 phase. Has no effect on subcellular location.1 Publication

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

PaxDbiO95600.
PRIDEiO95600.

PTM databases

PhosphoSiteiO95600.

Expressioni

Tissue specificityi

Ubiquitous.1 Publication

Gene expression databases

ArrayExpressiO95600.
BgeeiO95600.
CleanExiHS_KLF8.
GenevestigatoriO95600.

Interactioni

Subunit structurei

Interacts with corepressor CtBP2. Interacts with PIAS1, PIAS2, AND PIAS4; the interaction with each ligase sumoylates KLF8.2 Publications

Protein-protein interaction databases

BioGridi116435. 9 interactions.
IntActiO95600. 1 interaction.
MINTiMINT-7969747.
STRINGi9606.ENSP00000417303.

Structurei

3D structure databases

ProteinModelPortaliO95600.
SMRiO95600. Positions 274-356.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiCOG5048.
HOVERGENiHBG003941.
InParanoidiO95600.
KOiK09205.
OMAiPVQIRDP.
OrthoDBiEOG7Z69CW.
PhylomeDBiO95600.
TreeFamiTF350556.

Family and domain databases

Gene3Di3.30.160.60. 3 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 3 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 3 hits.
PS50157. ZINC_FINGER_C2H2_2. 3 hits.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

This entry describes 4 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: O95600-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MVDMDKLINN LEVQLNSEGG SMQVFKQVTA SVRNRDPPEI EYRSNMTSPT    50
LLDANPMENP ALFNDIKIEP PEELLASDFS LPQVEPVDLS FHKPKAPLQP 100
ASMLQAPIRP PKPQSSPQTL VVSTSTSDMS TSANIPTVLT PGSVLTSSQS 150
TGSQQILHVI HTIPSVSLPN KMGGLKTIPV VVQSLPMVYT TLPADGGPAA 200
ITVPLIGGDG KNAGSVKVDP TSMSPLEIPS DSEESTIESG SSALQSLQGL 250
QQEPAAMAQM QGEESLDLKR RRIHQCDFAG CSKVYTKSSH LKAHRRIHTG 300
EKPYKCTWDG CSWKFARSDE LTRHFRKHTG IKPFRCTDCN RSFSRSDHLS 350
LHRRRHDTM 359
Length:359
Mass (Da):39,314
Last modified:November 2, 2001 - v2
Checksum:iF8FDCC1FD477C04F
GO
Isoform 2 (identifier: O95600-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     254-359: PAAMAQMQGE...SLHRRRHDTM → REAL

Show »
Length:257
Mass (Da):27,242
Checksum:i86CF13DBD7494270
GO
Isoform 3 (identifier: O95600-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-27: MVDMDKLINNLEVQLNSEGGSMQVFKQ → MSLPEDGMSSGHFRSPQLVTWS
     254-359: PAAMAQMQGE...SLHRRRHDTM → REAL

Show »
Length:252
Mass (Da):26,623
Checksum:i0B68B09E33AC87A8
GO
Isoform 4 (identifier: O95600-5) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     216-299: Missing.

Show »
Length:275
Mass (Da):30,050
Checksum:i7CB5F2431F0E06D0
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 2727MVDMD…QVFKQ → MSLPEDGMSSGHFRSPQLVT WS in isoform 3.
VSP_047480Add
BLAST
Alternative sequencei216 – 29984Missing in isoform 4.
VSP_047481Add
BLAST
Alternative sequencei254 – 359106PAAMA…RHDTM → REAL in isoform 2 and isoform 3.
VSP_045460Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti167 – 1671S → I in BAG58895. 1 Publication
Sequence conflicti263 – 2631E → G in AAC99849. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U28282 mRNA. Translation: AAC99849.1.
HF546207 mRNA. Translation: CCO02793.1.
HF546208 mRNA. Translation: CCO02794.1.
HF546209 mRNA. Translation: CCO02795.1.
AK296156 mRNA. Translation: BAG58895.1.
AB209004 mRNA. Translation: BAD92241.1. Sequence problems.
BX641066 mRNA. Translation: CAE46033.1. Sequence problems.
BX322609, AL050309 Genomic DNA. Translation: CAI41397.1.
AL050309, BX322609 Genomic DNA. Translation: CAI42343.1.
BC105130 mRNA. Translation: AAI05131.1.
BC112109 mRNA. Translation: AAI12110.1.
CCDSiCCDS14373.1. [O95600-1]
CCDS55428.1. [O95600-3]
RefSeqiNP_001152768.1. NM_001159296.1. [O95600-3]
NP_009181.2. NM_007250.4. [O95600-1]
XP_005262034.1. XM_005261977.1. [O95600-1]
XP_005262035.1. XM_005261978.1. [O95600-1]
XP_005262036.1. XM_005261979.1. [O95600-1]
XP_006724638.1. XM_006724575.1. [O95600-3]
UniGeneiHs.646614.

Genome annotation databases

EnsembliENST00000374928; ENSP00000364063; ENSG00000102349. [O95600-3]
ENST00000468660; ENSP00000417303; ENSG00000102349. [O95600-1]
GeneIDi11279.
KEGGihsa:11279.
UCSCiuc004dur.3. human. [O95600-1]
uc011mop.2. human.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U28282 mRNA. Translation: AAC99849.1 .
HF546207 mRNA. Translation: CCO02793.1 .
HF546208 mRNA. Translation: CCO02794.1 .
HF546209 mRNA. Translation: CCO02795.1 .
AK296156 mRNA. Translation: BAG58895.1 .
AB209004 mRNA. Translation: BAD92241.1 . Sequence problems.
BX641066 mRNA. Translation: CAE46033.1 . Sequence problems.
BX322609 , AL050309 Genomic DNA. Translation: CAI41397.1 .
AL050309 , BX322609 Genomic DNA. Translation: CAI42343.1 .
BC105130 mRNA. Translation: AAI05131.1 .
BC112109 mRNA. Translation: AAI12110.1 .
CCDSi CCDS14373.1. [O95600-1 ]
CCDS55428.1. [O95600-3 ]
RefSeqi NP_001152768.1. NM_001159296.1. [O95600-3 ]
NP_009181.2. NM_007250.4. [O95600-1 ]
XP_005262034.1. XM_005261977.1. [O95600-1 ]
XP_005262035.1. XM_005261978.1. [O95600-1 ]
XP_005262036.1. XM_005261979.1. [O95600-1 ]
XP_006724638.1. XM_006724575.1. [O95600-3 ]
UniGenei Hs.646614.

3D structure databases

ProteinModelPortali O95600.
SMRi O95600. Positions 274-356.
ModBasei Search...

Protein-protein interaction databases

BioGridi 116435. 9 interactions.
IntActi O95600. 1 interaction.
MINTi MINT-7969747.
STRINGi 9606.ENSP00000417303.

PTM databases

PhosphoSitei O95600.

Proteomic databases

PaxDbi O95600.
PRIDEi O95600.

Protocols and materials databases

DNASUi 11279.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000374928 ; ENSP00000364063 ; ENSG00000102349 . [O95600-3 ]
ENST00000468660 ; ENSP00000417303 ; ENSG00000102349 . [O95600-1 ]
GeneIDi 11279.
KEGGi hsa:11279.
UCSCi uc004dur.3. human. [O95600-1 ]
uc011mop.2. human.

Organism-specific databases

CTDi 11279.
GeneCardsi GC0XP056275.
HGNCi HGNC:6351. KLF8.
MIMi 300286. gene.
neXtProti NX_O95600.
PharmGKBi PA30141.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG5048.
HOVERGENi HBG003941.
InParanoidi O95600.
KOi K09205.
OMAi PVQIRDP.
OrthoDBi EOG7Z69CW.
PhylomeDBi O95600.
TreeFami TF350556.

Miscellaneous databases

GeneWikii KLF8.
GenomeRNAii 11279.
NextBioi 42937.
PROi O95600.
SOURCEi Search...

Gene expression databases

ArrayExpressi O95600.
Bgeei O95600.
CleanExi HS_KLF8.
Genevestigatori O95600.

Family and domain databases

Gene3Di 3.30.160.60. 3 hits.
InterProi IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view ]
SMARTi SM00355. ZnF_C2H2. 3 hits.
[Graphical view ]
PROSITEi PS00028. ZINC_FINGER_C2H2_1. 3 hits.
PS50157. ZINC_FINGER_C2H2_2. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Gorski J.L., MacDonald M., Vananthwerp M., Burright E.N., Bialecki M.
    Submitted (JUN-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
  2. "Shaking the family tree: Identification of novel and biologically active alternatively spliced isoforms across the KLF family of transcription factors."
    Camacho-Vanegas O., Till J., Miranda-Lorenzo I., Ozturk B., Camacho S.C., Martignetti J.A.
    FASEB J. 27:432-436(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2; 3 AND 4), ALTERNATIVE SPLICING.
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Thalamus.
  4. Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Brain.
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Uterus.
  6. "The DNA sequence of the human X chromosome."
    Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
    , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
    Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Brain.
  8. "Human Kruppel-like factor 8: a CACCC-box binding protein that associates with CtBP and represses transcription."
    van Vliet J., Turner J., Crossley M.
    Nucleic Acids Res. 28:1955-1962(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBUNIT, TISSUE SPECIFICITY.
  9. "Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progression."
    Zhao J., Bian Z.C., Yee K., Chen B.P., Chien S., Guan J.L.
    Mol. Cell 11:1503-1515(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  10. "Sumoylation delimits KLF8 transcriptional activity associated with the cell cycle regulation."
    Wei H., Wang X., Gan B., Urvalek A.M., Melkoumian Z.K., Guan J.-L., Zhao J.
    J. Biol. Chem. 281:16664-16671(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUMOYLATION AT LYS-67, INTERACTION WITH PIAS1; PIAS2 AND PIAS4, FUNCTION, SUBCELLULAR LOCATION, MUTAGENESIS OF LYS-67 AND LYS-217.

Entry informationi

Entry nameiKLF8_HUMAN
AccessioniPrimary (citable) accession number: O95600
Secondary accession number(s): B4DJN3
, E7EQQ8, L0R3U8, L0R4U2, Q2M246, Q59GV5, Q5HYQ5, Q5JXP7, Q6MZJ7, Q9UGC4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: November 2, 2001
Last modified: July 9, 2014
This is version 121 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi