Reviewed, UniProtKB/Swiss-Prot O95567 (CV031_HUMAN)

Names and origin

Protein names

Recommended name:
    Uncharacterized protein C22orf31

Gene names

Name:

C22orf31

Organism

Homo sapiens (Human) [Complete proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	290 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 290	290	Uncharacterized protein C22orf31		PRO_0000254057
Natural variations
	Natural variant	46	1	C → R: dbSNP rs9625679.		VAR_028808
	Natural variant	210	1	T → R: dbSNP rs714136.		VAR_028809

Sequences

	Sequence		Length	Mass (Da)
	O95567-1 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: DD641137D3C38518	FASTA	290	32,655
	10 20 30 40 50 60 MHPINVRRDP SIPIYGLRQS ILLNTRLQDC YVDSPALTNI WMARTCAKQN INAPAPATTS 70 80 90 100 110 120 SWEVVRNPLI ASSFSLVKLV LRRQLKNKCC PPPCKFGEGK LSKRLKHKDD SVMKATQQAR 130 140 150 160 170 180 KRNFISSKSK QPAGHRRPAG GIRESKESSK EKKLTVRQDL EDRYAEHVAA TQALPQDSGT 190 200 210 220 230 240 AAWKGRVLLP ETQKRQQLSE DTLTIHGLPT EGYQALYHAV VEPMLWNPSG TPKRYSLELG 250 260 270 280 290 KAIKQKLWEA LCSQGAISEG AQRDRFPGRK QPGVHEEPVL KKWPKLKSKK

References

[1]	"Reevaluating human gene annotation: a second-generation analysis of chromosome 22." Collins J.E., Goward M.E., Cole C.G., Smink L.J., Huckle E.J., Knowles S., Bye J.M., Beare D.M., Dunham I. Genome Res. 13:27-36(2003) [PubMed: 12529303] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[2]	"A genome annotation-driven approach to cloning the human ORFeome." Collins J.E., Wright C.L., Edwards C.A., Davis M.P., Grinham J.A., Cole C.G., Goward M.E., Aguado B., Mallya M., Mokrab Y., Huckle E.J., Beare D.M., Dunham I. Genome Biol. 5:R84.1-R84.11(2004) [PubMed: 15461802] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Testis.
[3]	"The DNA sequence of human chromosome 22." Dunham I., Hunt A.R., Collins J.E., Bruskiewich R., Beare D.M., Clamp M., Smink L.J., Ainscough R., Almeida J.P., Babbage A.K., Bagguley C., Bailey J., Barlow K.F., Bates K.N., Beasley O.P., Bird C.P., Blakey S.E., Bridgeman A.M. , Buck D., Burgess J., Burrill W.D., Burton J., Carder C., Carter N.P., Chen Y., Clark G., Clegg S.M., Cobley V.E., Cole C.G., Collier R.E., Connor R., Conroy D., Corby N.R., Coville G.J., Cox A.V., Davis J., Dawson E., Dhami P.D., Dockree C., Dodsworth S.J., Durbin R.M., Ellington A.G., Evans K.L., Fey J.M., Fleming K., French L., Garner A.A., Gilbert J.G.R., Goward M.E., Grafham D.V., Griffiths M.N.D., Hall C., Hall R.E., Hall-Tamlyn G., Heathcott R.W., Ho S., Holmes S., Hunt S.E., Jones M.C., Kershaw J., Kimberley A.M., King A., Laird G.K., Langford C.F., Leversha M.A., Lloyd C., Lloyd D.M., Martyn I.D., Mashreghi-Mohammadi M., Matthews L.H., Mccann O.T., Mcclay J., Mclaren S., McMurray A.A., Milne S.A., Mortimore B.J., Odell C.N., Pavitt R., Pearce A.V., Pearson D., Phillimore B.J.C.T., Phillips S.H., Plumb R.W., Ramsay H., Ramsey Y., Rogers L., Ross M.T., Scott C.E., Sehra H.K., Skuce C.D., Smalley S., Smith M.L., Soderlund C., Spragon L., Steward C.A., Sulston J.E., Swann R.M., Vaudin M., Wall M., Wallis J.M., Whiteley M.N., Willey D.L., Williams L., Williams S.A., Williamson H., Wilmer T.E., Wilming L., Wright C.L., Hubbard T., Bentley D.R., Beck S., Rogers J., Shimizu N., Minoshima S., Kawasaki K., Sasaki T., Asakawa S., Kudoh J., Shintani A., Shibuya K., Yoshizaki Y., Aoki N., Mitsuyama S., Roe B.A., Chen F., Chu L., Crabtree J., Deschamps S., Do A., Do T., Dorman A., Fang F., Fu Y., Hu P., Hua A., Kenton S., Lai H., Lao H.I., Lewis J., Lewis S., Lin S.-P., Loh P., Malaj E., Nguyen T., Pan H., Phan S., Qi S., Qian Y., Ray L., Ren Q., Shaull S., Sloan D., Song L., Wang Q., Wang Y., Wang Z., White J., Willingham D., Wu H., Yao Z., Zhan M., Zhang G., Chissoe S., Murray J., Miller N., Minx P., Fulton R., Johnson D., Bemis G., Bentley D., Bradshaw H., Bourne S., Cordes M., Du Z., Fulton L., Goela D., Graves T., Hawkins J., Hinds K., Kemp K., Latreille P., Layman D., Ozersky P., Rohlfing T., Scheet P., Walker C., Wamsley A., Wohldmann P., Pepin K., Nelson J., Korf I., Bedell J.A., Hillier L.W., Mardis E., Waterston R., Wilson R., Emanuel B.S., Shaikh T., Kurahashi H., Saitta S., Budarf M.L., McDermid H.E., Johnson A., Wong A.C.C., Morrow B.E., Edelmann L., Kim U.J., Shizuya H., Simon M.I., Dumanski J.P., Peyrard M., Kedra D., Seroussi E., Fransson I., Tapia I., Bruder C.E., O'Brien K.P., Wilkinson P., Bodenteich A., Hartman K., Hu X., Khan A.S., Lane L., Tilahun Y., Wright H. Nature 402:489-495(1999) [PubMed: 10591208] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Testis.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL035364 mRNA. Translation: CAA23017.1. CR456405 mRNA. Translation: CAG30291.1. AL021393 Genomic DNA. Translation: CAB62958.1. BC074758 mRNA. Translation: AAH74758.1. BC126262 mRNA. Translation: AAI26263.1. BC126264 mRNA. Translation: AAI26265.1.
IPI	IPI00294974.
RefSeq	NP_056185.1.
UniGene	Hs.50891
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	O95567.
Genome annotation databases
Ensembl	ENST00000216071; ENSP00000216071; ENSG00000100249; Homo sapiens. [Genome view]
GeneID	25770.
KEGG	hsa:25770.
UCSC	uc003aej.1. human.
Organism-specific databases
CTD	25770.
GeneCards	GC22M027784.
HGNC	HGNC:26931. C22orf31.
HPA	HPA000604.
GenAtlas	Search...
Phylogenomic databases
OMA	VEPMLWN
OrthoDB	EOG9JWZ08
Gene expression databases
ArrayExpress	O95567.
Bgee	O95567.
CleanEx	HS_C22orf31.
Genevestigator	O95567.
GermOnline	ENSG00000100249. Homo sapiens.
Family and domain databases
ProtoNet	Search...
Other Resources
NextBio	46897.

Entry information

Entry name

CV031_HUMAN

Accession

Primary (citable) accession number: O95567
Secondary accession number(s): A0AV97

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 31, 2006
Last sequence update:	May 1, 1999
Last modified:	November 24, 2009
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.