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O95561 (CA105_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized protein C1orf105
Gene names
Name:C1orf105
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length183 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

Ontologies

Keywords
   Coding sequence diversityPolymorphism
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 183183Uncharacterized protein C1orf105
PRO_0000251727

Natural variations

Natural variant971M → V.
Corresponds to variant rs16844498 [ dbSNP | Ensembl ].
VAR_027710
Natural variant1371S → N. Ref.3
Corresponds to variant rs1129942 [ dbSNP | Ensembl ].
VAR_027711

Sequences

Sequence LengthMass (Da)Tools
O95561 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: 665168CBB7409A30

FASTA18321,209
        10         20         30         40         50         60 
MEKRELKASV PKFDKIPWLS EASLVNKPLV LSLPRRYPHT SATFLTSSKK NMNLPILFQV 

        70         80         90        100        110        120 
PDVLSKARRN QCDSMLLRNQ QLCSTCQEMK MVQPRTMKIP DDPKASFENC MSYRMSLHQP 

       130        140        150        160        170        180 
KFQTTPEPFH DDIPTESIHY RLPILGPRTA VFHGLLTEAY KTLKERQRSS LPRKEPIGKT 


TRQ 

« Hide

References

[1]Rhodes S.
Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[2]"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. expand/collapse author list , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ASN-137.
Tissue: Brain.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL035295 mRNA. Translation: CAA22895.1.
Z97195 Genomic DNA. Translation: CAI19058.1.
BC038410 mRNA. Translation: AAH38410.1.
CCDSCCDS1301.1.
RefSeqNP_640333.3. NM_139240.3.
UniGeneHs.517991.

3D structure databases

ProteinModelPortalO95561.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid124939. 1 interaction.
STRING9606.ENSP00000356700.

PTM databases

PhosphoSiteO95561.

Proteomic databases

PaxDbO95561.
PRIDEO95561.

Protocols and materials databases

DNASU92346.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000367727; ENSP00000356700; ENSG00000180999.
GeneID92346.
KEGGhsa:92346.
UCSCuc001gik.3. human.

Organism-specific databases

CTD92346.
GeneCardsGC01P172389.
H-InvDBHIX0023854.
HGNCHGNC:29591. C1orf105.
HPAHPA028480.
neXtProtNX_O95561.
PharmGKBPA142672489.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG87534.
HOGENOMHOG000111241.
HOVERGENHBG080962.
InParanoidO95561.
OMARKNEHEN.
OrthoDBEOG7N0C60.
PhylomeDBO95561.
TreeFamTF336911.

Gene expression databases

ArrayExpressO95561.
BgeeO95561.
CleanExHS_C1orf105.
GenevestigatorO95561.

Family and domain databases

InterProIPR027845. DUF4548.
[Graphical view]
PfamPF15081. DUF4548. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi92346.
NextBio77722.

Entry information

Entry nameCA105_HUMAN
AccessionPrimary (citable) accession number: O95561
Secondary accession number(s): Q8IY02
Entry history
Integrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: May 1, 1999
Last modified: July 9, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 1

Human chromosome 1: entries, gene names and cross-references to MIM