Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uncharacterized protein C1orf105

Gene

C1orf105

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciZFISH:ENSG00000180999-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C1orf105
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:29591. C1orf105.

Pathology & Biotechi

Organism-specific databases

DisGeNETi92346.
OpenTargetsiENSG00000180999.
PharmGKBiPA142672489.

Polymorphism and mutation databases

BioMutaiC1orf105.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002517271 – 183Uncharacterized protein C1orf105Add BLAST183

Proteomic databases

PaxDbiO95561.
PRIDEiO95561.

PTM databases

iPTMnetiO95561.
PhosphoSitePlusiO95561.

Expressioni

Gene expression databases

BgeeiENSG00000180999.
CleanExiHS_C1orf105.
ExpressionAtlasiO95561. baseline and differential.
GenevisibleiO95561. HS.

Organism-specific databases

HPAiHPA028480.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
PSMA3P257883EBI-10191951,EBI-348380

Protein-protein interaction databases

BioGridi124939. 4 interactors.
IntActiO95561. 1 interactor.
STRINGi9606.ENSP00000356700.

Structurei

3D structure databases

ProteinModelPortaliO95561.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410J039. Eukaryota.
ENOG4111810. LUCA.
GeneTreeiENSGT00390000015231.
HOGENOMiHOG000111241.
HOVERGENiHBG080962.
InParanoidiO95561.
OMAiPWFSEAS.
OrthoDBiEOG091G0PML.
PhylomeDBiO95561.
TreeFamiTF336911.

Family and domain databases

InterProiIPR027845. DUF4548.
[Graphical view]
PANTHERiPTHR39410. PTHR39410. 1 hit.
PfamiPF15081. DUF4548. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O95561-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKRELKASV PKFDKIPWLS EASLVNKPLV LSLPRRYPHT SATFLTSSKK
60 70 80 90 100
NMNLPILFQV PDVLSKARRN QCDSMLLRNQ QLCSTCQEMK MVQPRTMKIP
110 120 130 140 150
DDPKASFENC MSYRMSLHQP KFQTTPEPFH DDIPTESIHY RLPILGPRTA
160 170 180
VFHGLLTEAY KTLKERQRSS LPRKEPIGKT TRQ
Length:183
Mass (Da):21,209
Last modified:May 1, 1999 - v1
Checksum:i665168CBB7409A30
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_02771097M → V.Corresponds to variant rs16844498dbSNPEnsembl.1
Natural variantiVAR_027711137S → N.1 PublicationCorresponds to variant rs1129942dbSNPEnsembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL035295 mRNA. Translation: CAA22895.1.
Z97195 Genomic DNA. Translation: CAI19058.1.
BC038410 mRNA. Translation: AAH38410.1.
CCDSiCCDS1301.1.
RefSeqiNP_640333.3. NM_139240.3.
UniGeneiHs.517991.

Genome annotation databases

EnsembliENST00000367727; ENSP00000356700; ENSG00000180999.
GeneIDi92346.
KEGGihsa:92346.
UCSCiuc001gik.3. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL035295 mRNA. Translation: CAA22895.1.
Z97195 Genomic DNA. Translation: CAI19058.1.
BC038410 mRNA. Translation: AAH38410.1.
CCDSiCCDS1301.1.
RefSeqiNP_640333.3. NM_139240.3.
UniGeneiHs.517991.

3D structure databases

ProteinModelPortaliO95561.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi124939. 4 interactors.
IntActiO95561. 1 interactor.
STRINGi9606.ENSP00000356700.

PTM databases

iPTMnetiO95561.
PhosphoSitePlusiO95561.

Polymorphism and mutation databases

BioMutaiC1orf105.

Proteomic databases

PaxDbiO95561.
PRIDEiO95561.

Protocols and materials databases

DNASUi92346.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000367727; ENSP00000356700; ENSG00000180999.
GeneIDi92346.
KEGGihsa:92346.
UCSCiuc001gik.3. human.

Organism-specific databases

CTDi92346.
DisGeNETi92346.
GeneCardsiC1orf105.
H-InvDBHIX0023854.
HGNCiHGNC:29591. C1orf105.
HPAiHPA028480.
neXtProtiNX_O95561.
OpenTargetsiENSG00000180999.
PharmGKBiPA142672489.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410J039. Eukaryota.
ENOG4111810. LUCA.
GeneTreeiENSGT00390000015231.
HOGENOMiHOG000111241.
HOVERGENiHBG080962.
InParanoidiO95561.
OMAiPWFSEAS.
OrthoDBiEOG091G0PML.
PhylomeDBiO95561.
TreeFamiTF336911.

Enzyme and pathway databases

BioCyciZFISH:ENSG00000180999-MONOMER.

Miscellaneous databases

GenomeRNAii92346.
PROiO95561.

Gene expression databases

BgeeiENSG00000180999.
CleanExiHS_C1orf105.
ExpressionAtlasiO95561. baseline and differential.
GenevisibleiO95561. HS.

Family and domain databases

InterProiIPR027845. DUF4548.
[Graphical view]
PANTHERiPTHR39410. PTHR39410. 1 hit.
PfamiPF15081. DUF4548. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCA105_HUMAN
AccessioniPrimary (citable) accession number: O95561
Secondary accession number(s): Q8IY02
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: May 1, 1999
Last modified: November 2, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.