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O95561

- CA105_HUMAN

UniProt

O95561 - CA105_HUMAN

Protein

Uncharacterized protein C1orf105

Gene

C1orf105

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 80 (01 Oct 2014)
      Sequence version 1 (01 May 1999)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized protein C1orf105
    Gene namesi
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 1

    Organism-specific databases

    HGNCiHGNC:29591. C1orf105.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA142672489.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 183183Uncharacterized protein C1orf105PRO_0000251727Add
    BLAST

    Proteomic databases

    PaxDbiO95561.
    PRIDEiO95561.

    PTM databases

    PhosphoSiteiO95561.

    Expressioni

    Gene expression databases

    ArrayExpressiO95561.
    BgeeiO95561.
    CleanExiHS_C1orf105.
    GenevestigatoriO95561.

    Organism-specific databases

    HPAiHPA028480.

    Interactioni

    Protein-protein interaction databases

    BioGridi124939. 1 interaction.
    STRINGi9606.ENSP00000356700.

    Structurei

    3D structure databases

    ProteinModelPortaliO95561.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG87534.
    HOGENOMiHOG000111241.
    HOVERGENiHBG080962.
    InParanoidiO95561.
    OMAiRKNEHEN.
    OrthoDBiEOG7N0C60.
    PhylomeDBiO95561.
    TreeFamiTF336911.

    Family and domain databases

    InterProiIPR027845. DUF4548.
    [Graphical view]
    PfamiPF15081. DUF4548. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O95561-1 [UniParc]FASTAAdd to Basket

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    MEKRELKASV PKFDKIPWLS EASLVNKPLV LSLPRRYPHT SATFLTSSKK    50
    NMNLPILFQV PDVLSKARRN QCDSMLLRNQ QLCSTCQEMK MVQPRTMKIP 100
    DDPKASFENC MSYRMSLHQP KFQTTPEPFH DDIPTESIHY RLPILGPRTA 150
    VFHGLLTEAY KTLKERQRSS LPRKEPIGKT TRQ 183
    Length:183
    Mass (Da):21,209
    Last modified:May 1, 1999 - v1
    Checksum:i665168CBB7409A30
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti97 – 971M → V.
    Corresponds to variant rs16844498 [ dbSNP | Ensembl ].
    VAR_027710
    Natural varianti137 – 1371S → N.1 Publication
    Corresponds to variant rs1129942 [ dbSNP | Ensembl ].
    VAR_027711

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL035295 mRNA. Translation: CAA22895.1.
    Z97195 Genomic DNA. Translation: CAI19058.1.
    BC038410 mRNA. Translation: AAH38410.1.
    CCDSiCCDS1301.1.
    RefSeqiNP_640333.3. NM_139240.3.
    UniGeneiHs.517991.

    Genome annotation databases

    EnsembliENST00000367727; ENSP00000356700; ENSG00000180999.
    GeneIDi92346.
    KEGGihsa:92346.
    UCSCiuc001gik.3. human.

    Keywords - Coding sequence diversityi

    Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL035295 mRNA. Translation: CAA22895.1 .
    Z97195 Genomic DNA. Translation: CAI19058.1 .
    BC038410 mRNA. Translation: AAH38410.1 .
    CCDSi CCDS1301.1.
    RefSeqi NP_640333.3. NM_139240.3.
    UniGenei Hs.517991.

    3D structure databases

    ProteinModelPortali O95561.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 124939. 1 interaction.
    STRINGi 9606.ENSP00000356700.

    PTM databases

    PhosphoSitei O95561.

    Proteomic databases

    PaxDbi O95561.
    PRIDEi O95561.

    Protocols and materials databases

    DNASUi 92346.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000367727 ; ENSP00000356700 ; ENSG00000180999 .
    GeneIDi 92346.
    KEGGi hsa:92346.
    UCSCi uc001gik.3. human.

    Organism-specific databases

    CTDi 92346.
    GeneCardsi GC01P172389.
    H-InvDB HIX0023854.
    HGNCi HGNC:29591. C1orf105.
    HPAi HPA028480.
    neXtProti NX_O95561.
    PharmGKBi PA142672489.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG87534.
    HOGENOMi HOG000111241.
    HOVERGENi HBG080962.
    InParanoidi O95561.
    OMAi RKNEHEN.
    OrthoDBi EOG7N0C60.
    PhylomeDBi O95561.
    TreeFami TF336911.

    Miscellaneous databases

    GenomeRNAii 92346.
    NextBioi 77722.

    Gene expression databases

    ArrayExpressi O95561.
    Bgeei O95561.
    CleanExi HS_C1orf105.
    Genevestigatori O95561.

    Family and domain databases

    InterProi IPR027845. DUF4548.
    [Graphical view ]
    Pfami PF15081. DUF4548. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Rhodes S.
      Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    2. "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
      , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
      Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ASN-137.
      Tissue: Brain.

    Entry informationi

    Entry nameiCA105_HUMAN
    AccessioniPrimary (citable) accession number: O95561
    Secondary accession number(s): Q8IY02
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 3, 2006
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 1
      Human chromosome 1: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations

    External Data

    Dasty 3