Reviewed, UniProtKB/Swiss-Prot O95490 (LPHN2_HUMAN)

Names and origin

Protein names

Recommended name:
    Latrophilin-2
Alternative name(s):
    Calcium-independent alpha-latrotoxin receptor 2
    Latrophilin homolog 1
    Lectomedin-1

Gene names

Name:	LPHN2
Synonyms:	KIAA0786, LEC1, LPHH1

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1459 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Calcium-independent receptor of low affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor propably implicated in the regulation of exocytosis By similarity.
Subunit structure	Forms a heterodimer, consisting of a large extracellular region (p120) non-covalently linked to a seven-transmembrane moiety (p85) By similarity.
Subcellular location	Cell membrane; Multi-pass membrane protein.
Tissue specificity	Expressed very widely in all normal tissues tested. Expression is variable in tumor cell lines, apparently elevated in some lines and absent or markedly reduced in others.
Post-translational modification	Proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit By similarity.
Sequence similarities	Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 1 GPS domain. Contains 1 olfactomedin-like domain. Contains 1 SUEL-type lectin domain.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Coding sequence diversity	Alternative splicing
Domain	Signal Transmembrane
Ligand	Lectin
Molecular function	G-protein coupled receptor Receptor Transducer
PTM	Glycoprotein Phosphoprotein
Gene Ontology (GO)
Biological process	neuropeptide signaling pathway Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Ref.1 Non-traceable author statement. Source: UniProtKB plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	G-protein coupled receptor activity Inferred from electronic annotation. Source: InterPro latrotoxin receptor activity Ref.1 Non-traceable author statement. Source: UniProtKB sugar binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: O95490-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: O95490-2)

Also known as: Lectomedin-1 gamma;

The sequence of this isoform differs from the canonical sequence as follows:
     595-607: Missing.
     1167-1209: Missing.

Isoform 3 (identifier: O95490-3)

Also known as: Lectomedin-1 beta;

The sequence of this isoform differs from the canonical sequence as follows:
     595-607: Missing.
     1134-1136: SRI → DIH
     1137-1459: Missing.

Isoform 4 (identifier: O95490-4)

Also known as: Lectomedin-1 alpha;

The sequence of this isoform differs from the canonical sequence as follows:
     595-607: Missing.
     1167-1209: Missing.
     1210-1233: HSLNNARDTSAMDTLPLNGNFNNS → LTSHGLRAHLQDLYHLELLLGQIA
     1234-1459: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 25	25	Potential
	Chain	26 – 1459	1434	Latrophilin-2		PRO_0000012910
Regions
	Topological domain	39 – 851	813	Extracellular Potential
	Transmembrane	852 – 872	21	1 Potential
	Topological domain	873 – 880	8	Cytoplasmic Potential
	Transmembrane	881 – 901	21	2 Potential
	Topological domain	902 – 907	6	Extracellular Potential
	Transmembrane	908 – 928	21	3 Potential
	Topological domain	929 – 952	24	Cytoplasmic Potential
	Transmembrane	953 – 973	21	4 Potential
	Topological domain	974 – 990	17	Extracellular Potential
	Transmembrane	991 – 1011	21	5 Potential
	Topological domain	1012 – 1037	26	Cytoplasmic Potential
	Transmembrane	1038 – 1058	21	6 Potential
	Topological domain	1059 – 1062	4	Extracellular Potential
	Transmembrane	1063 – 1083	21	7 Potential
	Topological domain	1084 – 1459	376	Cytoplasmic Potential
	Domain	41 – 130	90	SUEL-type lectin
	Domain	135 – 394	260	Olfactomedin-like
	Domain	784 – 836	53	GPS
Sites
	Site	824 – 825	2	Cleavage By similarity
Amino acid modifications
	Modified residue	1381	1	Phosphoserine By similarity
	Modified residue	1387	1	Phosphoserine By similarity
	Glycosylation	99	1	N-linked (GlcNAc...) Potential
	Glycosylation	331	1	N-linked (GlcNAc...) Potential
	Glycosylation	520	1	N-linked (GlcNAc...) Potential
	Glycosylation	629	1	N-linked (GlcNAc...) Potential
	Glycosylation	731	1	N-linked (GlcNAc...) Potential
	Glycosylation	744	1	N-linked (GlcNAc...) Potential
	Glycosylation	787	1	N-linked (GlcNAc...) Potential
	Glycosylation	792	1	N-linked (GlcNAc...) Potential
	Glycosylation	813	1	N-linked (GlcNAc...) Potential
	Disulfide bond	136 ↔ 318		By similarity
Natural variations
	Alternative sequence	595 – 607	13	Missing in isoform 2, isoform 3 and isoform 4.		VSP_010104
	Alternative sequence	1134 – 1136	3	SRI → DIH in isoform 3.		VSP_010105
	Alternative sequence	1137 – 1459	323	Missing in isoform 3.		VSP_010106
	Alternative sequence	1167 – 1209	43	Missing in isoform 2 and isoform 4.		VSP_010107
	Alternative sequence	1210 – 1233	24	HSLNN…NFNNS → LTSHGLRAHLQDLYHLELLL GQIA in isoform 4.		VSP_010108
	Alternative sequence	1234 – 1459	226	Missing in isoform 4.		VSP_010109

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified April 26, 2004. Version 2. Checksum: 30707B7C3C069029	FASTA	1,459	163,349
	10 20 30 40 50 60 MVSSGCRMRS LWFIIVISFL PNTEGFSRAA LPFGLVRREL SCEGYSIDLR CPGSDVIMIE 70 80 90 100 110 120 SANYGRTDDK ICDADPFQME NTDCYLPDAF KIMTQRCNNR TQCIVVTGSD VFPDPCPGTY 130 140 150 160 170 180 KYLEVQYECV PYIFVCPGTL KAIVDSPCIY EAEQKAGAWC KDPLQAADKI YFMPWTPYRT 190 200 210 220 230 240 DTLIEYASLE DFQNSRQTTT YKLPNRVDGT GFVVYDGAVF FNKERTRNIV KFDLRTRIKS 250 260 270 280 290 300 GEAIINYANY HDTSPYRWGG KTDIDLAVDE NGLWVIYATE QNNGMIVISQ LNPYTLRFEA 310 320 330 340 350 360 TWETVYDKRA ASNAFMICGV LYVVRSVYQD NESETGKNSI DYIYNTRLNR GEYVDVPFPN 370 380 390 400 410 420 QYQYIAAVDY NPRDNQLYVW NNNFILRYSL EFGPPDPAQV PTTAVTITSS AELFKTIIST 430 440 450 460 470 480 TSTTSQKGPM STTVAGSQEG SKGTKPPPAV STTKIPPITN IFPLPERFCE ALDSKGIKWP 490 500 510 520 530 540 QTQRGMMVER PCPKGTRGTA SYLCMISTGT WNPKGPDLSN CTSHWVNQLA QKIRSGENAA 550 560 570 580 590 600 SLANELAKHT KGPVFAGDVS SSVRLMEQLV DILDAQLQEL KPSEKDSAGR SYNKLQKREK 610 620 630 640 650 660 TCRAYLKAIV DTVDNLLRPE ALESWKHMNS SEQAHTATML LDTLEEGAFV LADNLLEPTR 670 680 690 700 710 720 VSMPTENIVL EVAVLSTEGQ IQDFKFPLGI KGAGSSIQLS ANTVKQNSRN GLAKLVFIIY 730 740 750 760 770 780 RSLGQFLSTE NATIKLGADF IGRNSTIAVN SHVISVSINK ESSRVYLTDP VLFTLPHIDP 790 800 810 820 830 840 DNYFNANCSF WNYSERTMMG YWSTQGCKLV DTNKTRTTCA CSHLTNFAIL MAHREIAYKD 850 860 870 880 890 900 GVHELLLTVI TWVGIVISLV CLAICIFTFC FFRGLQSDRN TIHKNLCINL FIAEFIFLIG 910 920 930 940 950 960 IDKTKYAIAC PIFAGLLHFF FLAAFAWMCL EGVQLYLMLV EVFESEYSRK KYYYVAGYLF 970 980 990 1000 1010 1020 PATVVGVSAA IDYKSYGTEK ACWLHVDNYF IWSFIGPVTF IILLNIIFLV ITLCKMVKHS 1030 1040 1050 1060 1070 1080 NTLKPDSSRL ENIKSWVLGA FALLCLLGLT WSFGLLFINE ETIVMAYLFT IFNAFQGVFI 1090 1100 1110 1120 1130 1140 FIFHCALQKK VRKEYGKCFR HSYCCGGLPT ESPHSSVKAS TTRTSARYSS GTQSRIRRMW 1150 1160 1170 1180 1190 1200 NDTVRKQSES SFISGDINST STLNQGMTGN YLLTNPLLRP HGTNNPYNTL LAETVVCNAP 1210 1220 1230 1240 1250 1260 SAPVFNSPGH SLNNARDTSA MDTLPLNGNF NNSYSLHKGD YNDSVQVVDC GLSLNDTAFE 1270 1280 1290 1300 1310 1320 KMIISELVHN NLRGSSKTHN LELTLPVKPV IGGSSSEDDA IVADASSLMH SDNPGLELHH 1330 1340 1350 1360 1370 1380 KELEAPLIPQ RTHSLLYQPQ KKVKSEGTDS YVSQLTAEAE DHLQSPNRDS LYTSMPNLRD 1390 1400 1410 1420 1430 1440 SPYPESSPDM EEDLSPSRRS ENEDIYYKSM PNLGAGHQLQ MCYQISRGNS DGYIIPINKE 1450 GCIPEGDVRE GQMQLVTSL
	Isoform 2 (Lectomedin-1 gamma) [UniParc]. Checksum: CE43AB82916D0D35		1,403	157,178
	10 20 30 40 50 60 MVSSGCRMRS LWFIIVISFL PNTEGFSRAA LPFGLVRREL SCEGYSIDLR CPGSDVIMIE 70 80 90 100 110 120 SANYGRTDDK ICDADPFQME NTDCYLPDAF KIMTQRCNNR TQCIVVTGSD VFPDPCPGTY 130 140 150 160 170 180 KYLEVQYECV PYIFVCPGTL KAIVDSPCIY EAEQKAGAWC KDPLQAADKI YFMPWTPYRT 190 200 210 220 230 240 DTLIEYASLE DFQNSRQTTT YKLPNRVDGT GFVVYDGAVF FNKERTRNIV KFDLRTRIKS 250 260 270 280 290 300 GEAIINYANY HDTSPYRWGG KTDIDLAVDE NGLWVIYATE QNNGMIVISQ LNPYTLRFEA 310 320 330 340 350 360 TWETVYDKRA ASNAFMICGV LYVVRSVYQD NESETGKNSI DYIYNTRLNR GEYVDVPFPN 370 380 390 400 410 420 QYQYIAAVDY NPRDNQLYVW NNNFILRYSL EFGPPDPAQV PTTAVTITSS AELFKTIIST 430 440 450 460 470 480 TSTTSQKGPM STTVAGSQEG SKGTKPPPAV STTKIPPITN IFPLPERFCE ALDSKGIKWP 490 500 510 520 530 540 QTQRGMMVER PCPKGTRGTA SYLCMISTGT WNPKGPDLSN CTSHWVNQLA QKIRSGENAA 550 560 570 580 590 600 SLANELAKHT KGPVFAGDVS SSVRLMEQLV DILDAQLQEL KPSEKDSAGR SYNKAIVDTV 610 620 630 640 650 660 DNLLRPEALE SWKHMNSSEQ AHTATMLLDT LEEGAFVLAD NLLEPTRVSM PTENIVLEVA 670 680 690 700 710 720 VLSTEGQIQD FKFPLGIKGA GSSIQLSANT VKQNSRNGLA KLVFIIYRSL GQFLSTENAT 730 740 750 760 770 780 IKLGADFIGR NSTIAVNSHV ISVSINKESS RVYLTDPVLF TLPHIDPDNY FNANCSFWNY 790 800 810 820 830 840 SERTMMGYWS TQGCKLVDTN KTRTTCACSH LTNFAILMAH REIAYKDGVH ELLLTVITWV 850 860 870 880 890 900 GIVISLVCLA ICIFTFCFFR GLQSDRNTIH KNLCINLFIA EFIFLIGIDK TKYAIACPIF 910 920 930 940 950 960 AGLLHFFFLA AFAWMCLEGV QLYLMLVEVF ESEYSRKKYY YVAGYLFPAT VVGVSAAIDY 970 980 990 1000 1010 1020 KSYGTEKACW LHVDNYFIWS FIGPVTFIIL LNIIFLVITL CKMVKHSNTL KPDSSRLENI 1030 1040 1050 1060 1070 1080 KSWVLGAFAL LCLLGLTWSF GLLFINEETI VMAYLFTIFN AFQGVFIFIF HCALQKKVRK 1090 1100 1110 1120 1130 1140 EYGKCFRHSY CCGGLPTESP HSSVKASTTR TSARYSSGTQ SRIRRMWNDT VRKQSESSFI 1150 1160 1170 1180 1190 1200 SGDINSTSTL NQGHSLNNAR DTSAMDTLPL NGNFNNSYSL HKGDYNDSVQ VVDCGLSLND 1210 1220 1230 1240 1250 1260 TAFEKMIISE LVHNNLRGSS KTHNLELTLP VKPVIGGSSS EDDAIVADAS SLMHSDNPGL 1270 1280 1290 1300 1310 1320 ELHHKELEAP LIPQRTHSLL YQPQKKVKSE GTDSYVSQLT AEAEDHLQSP NRDSLYTSMP 1330 1340 1350 1360 1370 1380 NLRDSPYPES SPDMEEDLSP SRRSENEDIY YKSMPNLGAG HQLQMCYQIS RGNSDGYIIP 1390 1400 INKEGCIPEG DVREGQMQLV TSL
	Isoform 3 (Lectomedin-1 beta) [UniParc]. Checksum: 21DB98B51EBDF4EC		1,123	126,163
	10 20 30 40 50 60 MVSSGCRMRS LWFIIVISFL PNTEGFSRAA LPFGLVRREL SCEGYSIDLR CPGSDVIMIE 70 80 90 100 110 120 SANYGRTDDK ICDADPFQME NTDCYLPDAF KIMTQRCNNR TQCIVVTGSD VFPDPCPGTY 130 140 150 160 170 180 KYLEVQYECV PYIFVCPGTL KAIVDSPCIY EAEQKAGAWC KDPLQAADKI YFMPWTPYRT 190 200 210 220 230 240 DTLIEYASLE DFQNSRQTTT YKLPNRVDGT GFVVYDGAVF FNKERTRNIV KFDLRTRIKS 250 260 270 280 290 300 GEAIINYANY HDTSPYRWGG KTDIDLAVDE NGLWVIYATE QNNGMIVISQ LNPYTLRFEA 310 320 330 340 350 360 TWETVYDKRA ASNAFMICGV LYVVRSVYQD NESETGKNSI DYIYNTRLNR GEYVDVPFPN 370 380 390 400 410 420 QYQYIAAVDY NPRDNQLYVW NNNFILRYSL EFGPPDPAQV PTTAVTITSS AELFKTIIST 430 440 450 460 470 480 TSTTSQKGPM STTVAGSQEG SKGTKPPPAV STTKIPPITN IFPLPERFCE ALDSKGIKWP 490 500 510 520 530 540 QTQRGMMVER PCPKGTRGTA SYLCMISTGT WNPKGPDLSN CTSHWVNQLA QKIRSGENAA 550 560 570 580 590 600 SLANELAKHT KGPVFAGDVS SSVRLMEQLV DILDAQLQEL KPSEKDSAGR SYNKAIVDTV 610 620 630 640 650 660 DNLLRPEALE SWKHMNSSEQ AHTATMLLDT LEEGAFVLAD NLLEPTRVSM PTENIVLEVA 670 680 690 700 710 720 VLSTEGQIQD FKFPLGIKGA GSSIQLSANT VKQNSRNGLA KLVFIIYRSL GQFLSTENAT 730 740 750 760 770 780 IKLGADFIGR NSTIAVNSHV ISVSINKESS RVYLTDPVLF TLPHIDPDNY FNANCSFWNY 790 800 810 820 830 840 SERTMMGYWS TQGCKLVDTN KTRTTCACSH LTNFAILMAH REIAYKDGVH ELLLTVITWV 850 860 870 880 890 900 GIVISLVCLA ICIFTFCFFR GLQSDRNTIH KNLCINLFIA EFIFLIGIDK TKYAIACPIF 910 920 930 940 950 960 AGLLHFFFLA AFAWMCLEGV QLYLMLVEVF ESEYSRKKYY YVAGYLFPAT VVGVSAAIDY 970 980 990 1000 1010 1020 KSYGTEKACW LHVDNYFIWS FIGPVTFIIL LNIIFLVITL CKMVKHSNTL KPDSSRLENI 1030 1040 1050 1060 1070 1080 KSWVLGAFAL LCLLGLTWSF GLLFINEETI VMAYLFTIFN AFQGVFIFIF HCALQKKVRK 1090 1100 1110 1120 EYGKCFRHSY CCGGLPTESP HSSVKASTTR TSARYSSGTQ DIH
	Isoform 4 (Lectomedin-1 alpha) [UniParc]. Checksum: 6D099178841E1E3A		1,177	132,245
	10 20 30 40 50 60 MVSSGCRMRS LWFIIVISFL PNTEGFSRAA LPFGLVRREL SCEGYSIDLR CPGSDVIMIE 70 80 90 100 110 120 SANYGRTDDK ICDADPFQME NTDCYLPDAF KIMTQRCNNR TQCIVVTGSD VFPDPCPGTY 130 140 150 160 170 180 KYLEVQYECV PYIFVCPGTL KAIVDSPCIY EAEQKAGAWC KDPLQAADKI YFMPWTPYRT 190 200 210 220 230 240 DTLIEYASLE DFQNSRQTTT YKLPNRVDGT GFVVYDGAVF FNKERTRNIV KFDLRTRIKS 250 260 270 280 290 300 GEAIINYANY HDTSPYRWGG KTDIDLAVDE NGLWVIYATE QNNGMIVISQ LNPYTLRFEA 310 320 330 340 350 360 TWETVYDKRA ASNAFMICGV LYVVRSVYQD NESETGKNSI DYIYNTRLNR GEYVDVPFPN 370 380 390 400 410 420 QYQYIAAVDY NPRDNQLYVW NNNFILRYSL EFGPPDPAQV PTTAVTITSS AELFKTIIST 430 440 450 460 470 480 TSTTSQKGPM STTVAGSQEG SKGTKPPPAV STTKIPPITN IFPLPERFCE ALDSKGIKWP 490 500 510 520 530 540 QTQRGMMVER PCPKGTRGTA SYLCMISTGT WNPKGPDLSN CTSHWVNQLA QKIRSGENAA 550 560 570 580 590 600 SLANELAKHT KGPVFAGDVS SSVRLMEQLV DILDAQLQEL KPSEKDSAGR SYNKAIVDTV 610 620 630 640 650 660 DNLLRPEALE SWKHMNSSEQ AHTATMLLDT LEEGAFVLAD NLLEPTRVSM PTENIVLEVA 670 680 690 700 710 720 VLSTEGQIQD FKFPLGIKGA GSSIQLSANT VKQNSRNGLA KLVFIIYRSL GQFLSTENAT 730 740 750 760 770 780 IKLGADFIGR NSTIAVNSHV ISVSINKESS RVYLTDPVLF TLPHIDPDNY FNANCSFWNY 790 800 810 820 830 840 SERTMMGYWS TQGCKLVDTN KTRTTCACSH LTNFAILMAH REIAYKDGVH ELLLTVITWV 850 860 870 880 890 900 GIVISLVCLA ICIFTFCFFR GLQSDRNTIH KNLCINLFIA EFIFLIGIDK TKYAIACPIF 910 920 930 940 950 960 AGLLHFFFLA AFAWMCLEGV QLYLMLVEVF ESEYSRKKYY YVAGYLFPAT VVGVSAAIDY 970 980 990 1000 1010 1020 KSYGTEKACW LHVDNYFIWS FIGPVTFIIL LNIIFLVITL CKMVKHSNTL KPDSSRLENI 1030 1040 1050 1060 1070 1080 KSWVLGAFAL LCLLGLTWSF GLLFINEETI VMAYLFTIFN AFQGVFIFIF HCALQKKVRK 1090 1100 1110 1120 1130 1140 EYGKCFRHSY CCGGLPTESP HSSVKASTTR TSARYSSGTQ SRIRRMWNDT VRKQSESSFI 1150 1160 1170 SGDINSTSTL NQGLTSHGLR AHLQDLYHLE LLLGQIA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Isolation and characterisation of a human homologue of the latrophilin gene from a region of 1p31.1 implicated in breast cancer." White G.R.M., Varley J.M., Heighway J. Oncogene 17:3513-3519(1998) [PubMed: 10030676] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), TISSUE SPECIFICITY.
[2]	"Genomic structure and expression profile of LPHH1, a 7TM gene variably expressed in breast cancer cell lines." White G.R.M., Varley J.M., Heighway J. Biochim. Biophys. Acta 1491:75-92(2000) [PubMed: 10760572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]	Hayflick J.S. Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2; 3 AND 4).
[4]	"The DNA sequence and biological annotation of human chromosome 1." Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R. Nature 441:315-321(2006) [PubMed: 16710414] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	"Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." Nagase T., Ishikawa K., Suyama M., Kikuno R., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O. DNA Res. 5:277-286(1998) [PubMed: 9872452] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 439-1459 (ISOFORM 1). Tissue: Brain.

Web resources

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ131581 mRNA. Translation: CAA10458.1. AJ244492 , AJ244493, AJ244494, AJ244496, AJ244497, AJ244498, AJ244499, AJ244501, AJ244502, AJ244503, AJ244504, AJ244505, AJ244506, AJ244507, AJ244510, AJ244511, AJ244512<