O95153 (RIMB1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Peripheral-type benzodiazepine receptor-associated protein 1
Short name=PRAX-1

Alternative name(s):
Peripheral benzodiazepine receptor-interacting protein
Short name=PBR-IP
RIMS-binding protein 1
Short name=RIM-BP1

Gene names

Name:	BZRAP1
Synonyms:	KIAA0612, RBP1, RIMBP1

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1857 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	Interacts with RIMS1 and RIMS2 By similarity. Interacts with BZRP. Ref.1
Subcellular location	Cytoplasm. Mitochondrion. Note: Preferentially expressed in the mitochondria in the presence of BZRP. Ref.1
Tissue specificity	Predominantly expressed in brain, pituitary gland and thymus in adults. In adult brain, highest expression found in temporal lobe and the putamen, followed by amygdala, caudate nucleus, cerebral cortex, occipital and frontal lobe. A high expression level is also observed in fetal tissues like brain, heart, kidney and thymus. Ref.1
Domain	The SH3 and proline-rich domain is required for the interaction with BZRP and the second SH3 domain mediates binding to a proline-rich motif in RIMS1 and RIMS2 By similarity.
Sequence similarities	Belongs to the RIMBP family. Contains 3 fibronectin type-III domains. Contains 3 SH3 domains.
Caution	Ref.1 demonstrated interaction with BZRP but later PubMed:12435798 demonstrated in the rat ortholog that is not associated with BZRP in the brain.
Sequence caution	The sequence BAA31587.2 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Cellular component	Cytoplasm Mitochondrion
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Repeat SH3 domain
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	mitochondrion Inferred from direct assay Ref.1. Source: UniProtKB
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
CACNA1A	O00555	2	EBI-5915931,EBI-766279

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: O95153-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Note: No experimental confirmation available.

Isoform 2 (identifier: O95153-2)

The sequence of this isoform differs from the canonical sequence as follows:
     191-250: Missing.

Note: No experimental confirmation available.

Isoform 3 (identifier: O95153-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1849-1857: RTRRRRVQC → DWGCTTQGSPGPPGGPCTPSSGSAPRIERGEPQGRSEKVWGFFSKGKQLLRRLGSGKKE

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1857	1857	Peripheral-type benzodiazepine receptor-associated protein 1		PRO_0000221380
Regions
	Domain	653 – 720	68	SH3 1
	Domain	791 – 868	78	Fibronectin type-III 1
	Domain	882 – 955	74	Fibronectin type-III 2
	Domain	972 – 1066	95	Fibronectin type-III 3
	Domain	1625 – 1693	69	SH3 2
	Domain	1764 – 1831	68	SH3 3
	Compositional bias	1071 – 1150	80	Pro-rich
	Compositional bias	1262 – 1274	13	Poly-Glu
	Compositional bias	1334 – 1346	13	Poly-Glu
Amino acid modifications
	Modified residue	424	1	Phosphoserine By similarity
Natural variations
	Alternative sequence	191 – 250	60	Missing in isoform 2.		VSP_009204
	Alternative sequence	1849 – 1857	9	RTRRRRVQC → DWGCTTQGSPGPPGGPCTPS SGSAPRIERGEPQGRSEKVW GFFSKGKQLLRRLGSGKKE in isoform 3.		VSP_009205
	Natural variant	514	1	Q → R. Corresponds to variant rs2072145 [ dbSNP | Ensembl ].		VAR_017446
	Natural variant	586	1	A → T. Corresponds to variant rs2072147 [ dbSNP | Ensembl ].		VAR_017447
	Natural variant	817	1	Q → R. Ref.2 Corresponds to variant rs9913145 [ dbSNP | Ensembl ].		VAR_031662
	Natural variant	851	1	W → R. Ref.2 Corresponds to variant rs9905604 [ dbSNP | Ensembl ].		VAR_031663
	Natural variant	1118	1	H → L. Ref.2 Corresponds to variant rs3744099 [ dbSNP | Ensembl ].		VAR_017448
	Natural variant	1140	1	A → P. Ref.2 Corresponds to variant rs2680704 [ dbSNP | Ensembl ].		VAR_017449
	Natural variant	1253	1	R → C. Corresponds to variant rs3744101 [ dbSNP | Ensembl ].		VAR_017450
	Natural variant	1728	1	H → R. Ref.2 Corresponds to variant rs11079346 [ dbSNP | Ensembl ].		VAR_031664
	Natural variant	1830	1	G → E. Corresponds to variant rs2301868 [ dbSNP | Ensembl ].		VAR_017451
Experimental info
	Sequence conflict	1525	1	G → R in AAD11957. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified April 17, 2007. Version 2. Checksum: 594F850C95F9EE02	FASTA	1,857	200,051
	10 20 30 40 50 60 MEQLTTLPRP GDPGAMEPWA LPTWHSWTPG RGGEPSSAAP SIADTPPAAL QLQELRSEES 70 80 90 100 110 120 SKPKGDGSSR PVGGTDPEGA EACLPSLGQQ ASSSGPACQR PEDEEVEAFL KAKLNMSFGD 130 140 150 160 170 180 RPNLELLRAL GELRQRCAIL KEENQMLRKS SFPETEEKVR RLKRKNAELA VIAKRLEERA 190 200 210 220 230 240 RKLQETNLRV VSAPLPRPGT SLELCRKALA RQRARDLSET ASALLAKDKQ IAALQRECRE 250 260 270 280 290 300 LQARLTLVGK EGPQWLHVRD FDRLLRESQR EVLRLQRQIA LRNQRETLPL PPSWPPGPAL 310 320 330 340 350 360 QARAGAPAPG APGEATPQED ADNLPVILGE PEKEQRVQQL ESELSKKRKK CESLEQEARK 370 380 390 400 410 420 KQRRCEELEL QLRQAQNENA RLVEENSRLS GRATEKEQVE WENAELRGQL LGVTQERDSA 430 440 450 460 470 480 LRKSQGLQSK LESLEQVLKH MREVAQRRQQ LEVEHEQARL SLREKQEEVR RLQQAQAEAQ 490 500 510 520 530 540 REHEGAVQLL ESTLDSMQAR VRELEEQCRS QTEQFSLLAQ ELQAFRLHPG PLDLLTSALD 550 560 570 580 590 600 CGSLGDCPPP PCCCSIPQPC RGSGPKDLDL PPGSPGRCTP KSSEPAPATL TGVPRRTAKK 610 620 630 640 650 660 AESLSNSSHS ESIHNSPKSC PTPEVDTASE VEELEADSVS LLPAAPEGSR GGARIQVFLA 670 680 690 700 710 720 RYSYNPFEGP NENPEAELPL TAGEYIYIYG NMDEDGFFEG ELMDGRRGLV PSNFVERVSD 730 740 750 760 770 780 DDLLTSLPPE LADLSHSSGP ELSFLSVGGG GSSSGGQSSV GRSQPRPEEE DAGDELSLSP 790 800 810 820 830 840 SPEGLGEPPA VPYPRRLVVL KQLAHSVVLA WEPPPEQVEL HGFHICVNGE LRQALGPGAP 850 860 870 880 890 900 PKAVLENLDL WAGPLHISVQ ALTSRGSSDP LRCCLAVGAR AGVVPSQLRV HRLTATSAEI 910 920 930 940 950 960 TWVPGNSNLA HAIYLNGEEC PPASPSTYWA TFCHLRPGTP YQAQVEAQLP PQGPWEPGWE 970 980 990 1000 1010 1020 RLEQRAATLQ FTTLPAGPPD APLDVQIEPG PSPGILIISW LPVTIDAAGT SNGVRVTGYA 1030 1040 1050 1060 1070 1080 IYADGQKIME VASPTAGSVL VELSQLQLLQ VCREVVVRTM SPHGESADSI PAPITPALAP 1090 1100 1110 1120 1130 1140 ASLPARVSCP SPHPSPEARA PLASASPGPG DPSSPLQHPA PLGTQEPPGA PPASPSREMA 1150 1160 1170 1180 1190 1200 KGSHEDPPAP CSQEEAGAAV LGTSEERTAS TSTLGEKDPG PAAPSLAKQE AEWTAGEACP 1210 1220 1230 1240 1250 1260 ASSSTQGARA QQAPNTEMCQ GGDPGSGLRP RAEKEDTAEL GVHLVNSLVD HGRNSDLSDI 1270 1280 1290 1300 1310 1320 QEEEEEEEEE EEEELGSRTC SFQKQVAGNS IRENGAKSQP DPFCETDSDE EILEQILELP 1330 1340 1350 1360 1370 1380 LQQFCSKKLF SIPEEEEEEE EDEEEEKSGA GCSSRDPGPP EPALLGLGCD SGQPRRPGQC 1390 1400 1410 1420 1430 1440 PLSPESSRAG DCLEDMPGLV GGSSRRRGGG SPEKPPSRRR PPDPREHCSR LLSNNGPQAS 1450 1460 1470 1480 1490 1500 GRLGPTRERG GLPVIEGPRT GLEASGRGRL GPSRRCSRGR ALEPGLASCL SPKCLEISIE 1510 1520 1530 1540 1550 1560 YDSEDEQEAG SGGISITSSC YPGDGEAWGT ATVGRPRGPP KANSGPKPYP RLPAWEKGEP 1570 1580 1590 1600 1610 1620 ERRGRSATGR AKEPLSRATE TGEARGQDGS GRRGPQKRGV RVLRPSTAEL VPARSPSETL 1630 1640 1650 1660 1670 1680 AYQHLPVRIF VALFDYDPVS MSPNPDAGEE ELPFREGQIL KVFGDKDADG FYQGEGGGRT 1690 1700 1710 1720 1730 1740 GYIPCNMVAE VAVDSPAGRQ QLLQRGYLSP DILLEGSGNG PFVYSTAHTT GPPPKPRRSK 1750 1760 1770 1780 1790 1800 KAESEGPAQP CPGPPKLVPS ADLKAPHSMV AAFDYNPQES SPNMDVEAEL PFRAGDVITV 1810 1820 1830 1840 1850 FGGMDDDGFY YGELNGQRGL VPSNFLEGPG PEAGGLDREP RTPQAESQRT RRRRVQC
	Isoform 2 [UniParc]. Checksum: 8FD6E4FE89AA091F	FASTA	1,797	193,499
	10 20 30 40 50 60 MEQLTTLPRP GDPGAMEPWA LPTWHSWTPG RGGEPSSAAP SIADTPPAAL QLQELRSEES 70 80 90 100 110 120 SKPKGDGSSR PVGGTDPEGA EACLPSLGQQ ASSSGPACQR PEDEEVEAFL KAKLNMSFGD 130 140 150 160 170 180 RPNLELLRAL GELRQRCAIL KEENQMLRKS SFPETEEKVR RLKRKNAELA VIAKRLEERA 190 200 210 220 230 240 RKLQETNLRV EGPQWLHVRD FDRLLRESQR EVLRLQRQIA LRNQRETLPL PPSWPPGPAL 250 260 270 280 290 300 QARAGAPAPG APGEATPQED ADNLPVILGE PEKEQRVQQL ESELSKKRKK CESLEQEARK 310 320 330 340 350 360 KQRRCEELEL QLRQAQNENA RLVEENSRLS GRATEKEQVE WENAELRGQL LGVTQERDSA 370 380 390 400 410 420 LRKSQGLQSK LESLEQVLKH MREVAQRRQQ LEVEHEQARL SLREKQEEVR RLQQAQAEAQ 430 440 450 460 470 480 REHEGAVQLL ESTLDSMQAR VRELEEQCRS QTEQFSLLAQ ELQAFRLHPG PLDLLTSALD 490 500 510 520 530 540 CGSLGDCPPP PCCCSIPQPC RGSGPKDLDL PPGSPGRCTP KSSEPAPATL TGVPRRTAKK 550 560 570 580 590 600 AESLSNSSHS ESIHNSPKSC PTPEVDTASE VEELEADSVS LLPAAPEGSR GGARIQVFLA 610 620 630 640 650 660 RYSYNPFEGP NENPEAELPL TAGEYIYIYG NMDEDGFFEG ELMDGRRGLV PSNFVERVSD 670 680 690 700 710 720 DDLLTSLPPE LADLSHSSGP ELSFLSVGGG GSSSGGQSSV GRSQPRPEEE DAGDELSLSP 730 740 750 760 770 780 SPEGLGEPPA VPYPRRLVVL KQLAHSVVLA WEPPPEQVEL HGFHICVNGE LRQALGPGAP 790 800 810 820 830 840 PKAVLENLDL WAGPLHISVQ ALTSRGSSDP LRCCLAVGAR AGVVPSQLRV HRLTATSAEI 850 860 870 880 890 900 TWVPGNSNLA HAIYLNGEEC PPASPSTYWA TFCHLRPGTP YQAQVEAQLP PQGPWEPGWE 910 920 930 940 950 960 RLEQRAATLQ FTTLPAGPPD APLDVQIEPG PSPGILIISW LPVTIDAAGT SNGVRVTGYA 970 980 990 1000 1010 1020 IYADGQKIME VASPTAGSVL VELSQLQLLQ VCREVVVRTM SPHGESADSI PAPITPALAP 1030 1040 1050 1060 1070 1080 ASLPARVSCP SPHPSPEARA PLASASPGPG DPSSPLQHPA PLGTQEPPGA PPASPSREMA 1090 1100 1110 1120 1130 1140 KGSHEDPPAP CSQEEAGAAV LGTSEERTAS TSTLGEKDPG PAAPSLAKQE AEWTAGEACP 1150 1160 1170 1180 1190 1200 ASSSTQGARA QQAPNTEMCQ GGDPGSGLRP RAEKEDTAEL GVHLVNSLVD HGRNSDLSDI 1210 1220 1230 1240 1250 1260 QEEEEEEEEE EEEELGSRTC SFQKQVAGNS IRENGAKSQP DPFCETDSDE EILEQILELP 1270 1280 1290 1300 1310 1320 LQQFCSKKLF SIPEEEEEEE EDEEEEKSGA GCSSRDPGPP EPALLGLGCD SGQPRRPGQC 1330 1340 1350 1360 1370 1380 PLSPESSRAG DCLEDMPGLV GGSSRRRGGG SPEKPPSRRR PPDPREHCSR LLSNNGPQAS 1390 1400 1410 1420 1430 1440 GRLGPTRERG GLPVIEGPRT GLEASGRGRL GPSRRCSRGR ALEPGLASCL SPKCLEISIE 1450 1460 1470 1480 1490 1500 YDSEDEQEAG SGGISITSSC YPGDGEAWGT ATVGRPRGPP KANSGPKPYP RLPAWEKGEP 1510 1520 1530 1540 1550 1560 ERRGRSATGR AKEPLSRATE TGEARGQDGS GRRGPQKRGV RVLRPSTAEL VPARSPSETL 1570 1580 1590 1600 1610 1620 AYQHLPVRIF VALFDYDPVS MSPNPDAGEE ELPFREGQIL KVFGDKDADG FYQGEGGGRT 1630 1640 1650 1660 1670 1680 GYIPCNMVAE VAVDSPAGRQ QLLQRGYLSP DILLEGSGNG PFVYSTAHTT GPPPKPRRSK 1690 1700 1710 1720 1730 1740 KAESEGPAQP CPGPPKLVPS ADLKAPHSMV AAFDYNPQES SPNMDVEAEL PFRAGDVITV 1750 1760 1770 1780 1790 FGGMDDDGFY YGELNGQRGL VPSNFLEGPG PEAGGLDREP RTPQAESQRT RRRRVQC
	Isoform 3 [UniParc]. Checksum: 5034E93B8DB0E907	FASTA	1,907	205,050
	10 20 30 40 50 60 MEQLTTLPRP GDPGAMEPWA LPTWHSWTPG RGGEPSSAAP SIADTPPAAL QLQELRSEES 70 80 90 100 110 120 SKPKGDGSSR PVGGTDPEGA EACLPSLGQQ ASSSGPACQR PEDEEVEAFL KAKLNMSFGD 130 140 150 160 170 180 RPNLELLRAL GELRQRCAIL KEENQMLRKS SFPETEEKVR RLKRKNAELA VIAKRLEERA 190 200 210 220 230 240 RKLQETNLRV VSAPLPRPGT SLELCRKALA RQRARDLSET ASALLAKDKQ IAALQRECRE 250 260 270 280 290 300 LQARLTLVGK EGPQWLHVRD FDRLLRESQR EVLRLQRQIA LRNQRETLPL PPSWPPGPAL 310 320 330 340 350 360 QARAGAPAPG APGEATPQED ADNLPVILGE PEKEQRVQQL ESELSKKRKK CESLEQEARK 370 380 390 400 410 420 KQRRCEELEL QLRQAQNENA RLVEENSRLS GRATEKEQVE WENAELRGQL LGVTQERDSA 430 440 450 460 470 480 LRKSQGLQSK LESLEQVLKH MREVAQRRQQ LEVEHEQARL SLREKQEEVR RLQQAQAEAQ 490 500 510 520 530 540 REHEGAVQLL ESTLDSMQAR VRELEEQCRS QTEQFSLLAQ ELQAFRLHPG PLDLLTSALD 550 560 570 580 590 600 CGSLGDCPPP PCCCSIPQPC RGSGPKDLDL PPGSPGRCTP KSSEPAPATL TGVPRRTAKK 610 620 630 640 650 660 AESLSNSSHS ESIHNSPKSC PTPEVDTASE VEELEADSVS LLPAAPEGSR GGARIQVFLA 670 680 690 700 710 720 RYSYNPFEGP NENPEAELPL TAGEYIYIYG NMDEDGFFEG ELMDGRRGLV PSNFVERVSD 730 740 750 760 770 780 DDLLTSLPPE LADLSHSSGP ELSFLSVGGG GSSSGGQSSV GRSQPRPEEE DAGDELSLSP 790 800 810 820 830 840 SPEGLGEPPA VPYPRRLVVL KQLAHSVVLA WEPPPEQVEL HGFHICVNGE LRQALGPGAP 850 860 870 880 890 900 PKAVLENLDL WAGPLHISVQ ALTSRGSSDP LRCCLAVGAR AGVVPSQLRV HRLTATSAEI 910 920 930 940 950 960 TWVPGNSNLA HAIYLNGEEC PPASPSTYWA TFCHLRPGTP YQAQVEAQLP PQGPWEPGWE 970 980 990 1000 1010 1020 RLEQRAATLQ FTTLPAGPPD APLDVQIEPG PSPGILIISW LPVTIDAAGT SNGVRVTGYA 1030 1040 1050 1060 1070 1080 IYADGQKIME VASPTAGSVL VELSQLQLLQ VCREVVVRTM SPHGESADSI PAPITPALAP 1090 1100 1110 1120 1130 1140 ASLPARVSCP SPHPSPEARA PLASASPGPG DPSSPLQHPA PLGTQEPPGA PPASPSREMA 1150 1160 1170 1180 1190 1200 KGSHEDPPAP CSQEEAGAAV LGTSEERTAS TSTLGEKDPG PAAPSLAKQE AEWTAGEACP 1210 1220 1230 1240 1250 1260 ASSSTQGARA QQAPNTEMCQ GGDPGSGLRP RAEKEDTAEL GVHLVNSLVD HGRNSDLSDI 1270 1280 1290 1300 1310 1320 QEEEEEEEEE EEEELGSRTC SFQKQVAGNS IRENGAKSQP DPFCETDSDE EILEQILELP 1330 1340 1350 1360 1370 1380 LQQFCSKKLF SIPEEEEEEE EDEEEEKSGA GCSSRDPGPP EPALLGLGCD SGQPRRPGQC 1390 1400 1410 1420 1430 1440 PLSPESSRAG DCLEDMPGLV GGSSRRRGGG SPEKPPSRRR PPDPREHCSR LLSNNGPQAS 1450 1460 1470 1480 1490 1500 GRLGPTRERG GLPVIEGPRT GLEASGRGRL GPSRRCSRGR ALEPGLASCL SPKCLEISIE 1510 1520 1530 1540 1550 1560 YDSEDEQEAG SGGISITSSC YPGDGEAWGT ATVGRPRGPP KANSGPKPYP RLPAWEKGEP 1570 1580 1590 1600 1610 1620 ERRGRSATGR AKEPLSRATE TGEARGQDGS GRRGPQKRGV RVLRPSTAEL VPARSPSETL 1630 1640 1650 1660 1670 1680 AYQHLPVRIF VALFDYDPVS MSPNPDAGEE ELPFREGQIL KVFGDKDADG FYQGEGGGRT 1690 1700 1710 1720 1730 1740 GYIPCNMVAE VAVDSPAGRQ QLLQRGYLSP DILLEGSGNG PFVYSTAHTT GPPPKPRRSK 1750 1760 1770 1780 1790 1800 KAESEGPAQP CPGPPKLVPS ADLKAPHSMV AAFDYNPQES SPNMDVEAEL PFRAGDVITV 1810 1820 1830 1840 1850 1860 FGGMDDDGFY YGELNGQRGL VPSNFLEGPG PEAGGLDREP RTPQAESQDW GCTTQGSPGP 1870 1880 1890 1900 PGGPCTPSSG SAPRIERGEP QGRSEKVWGF FSKGKQLLRR LGSGKKE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning and characterization of PRAX-1. A new protein that specifically interacts with the peripheral benzodiazepine receptor." Galiegue S., Jbilo O., Combes T., Bribes E., Carayon P., Le Fur G., Casellas P. J. Biol. Chem. 274:2938-2952(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), SUBCELLULAR LOCATION, TISSUE SPECIFICITY, INTERACTION WITH BZRP. Tissue: Brain.
[2]	"Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro." Ishikawa K., Nagase T., Suyama M., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O. DNA Res. 5:169-176(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), VARIANTS ARG-817; ARG-851; LEU-1118; PRO-1140 AND ARG-1728. Tissue: Brain.
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1737-1857 (ISOFORM 3). Tissue: Brain.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF039571 mRNA. Translation: AAD11957.1. AB014512 mRNA. Translation: BAA31587.2. Different initiation. BC031401 mRNA. Translation: AAH31401.1.
IPI	IPI00006254. IPI00397514. IPI00397515.
PIR	T00391.
RefSeq	NP_001248764.1. NM_001261835.1. NP_004749.2. NM_004758.3. NP_077729.1. NM_024418.2.
UniGene	Hs.112499.
3D structure databases
ProteinModelPortal	O95153.
ModBase	Search...
Protein-protein interaction databases
IntAct	O95153. 1 interaction.
MINT	MINT-4132417.
STRING	9606.ENSP00000345824.
PTM databases
PhosphoSite	O95153.
Proteomic databases
PaxDb	O95153.
PRIDE	O95153.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000268893; ENSP00000268893; ENSG00000005379. ENST00000343736; ENSP00000345824; ENSG00000005379. ENST00000355701; ENSP00000347929; ENSG00000005379. ENST00000581675; ENSP00000462518; ENSG00000005379.
GeneID	9256.
KEGG	hsa:9256.
UCSC	uc002ivx.4. human. uc010dcs.3. human.
Organism-specific databases
CTD	9256.
GeneCards	GC17M056379.
H-InvDB	HIX0014027.
HGNC	HGNC:16831. BZRAP1.
HPA	HPA024662. HPA025244.
MIM	610764. gene.
neXtProt	NX_O95153.
PharmGKB	PA128394545.
HUGE	Search...
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG327664.
HOGENOM	HOG000139176.
HOVERGEN	HBG056664.
OMA	GSRTCSF.
Gene expression databases
Bgee	O95153.
CleanEx	HS_BZRAP1. HS_RBP1.
Genevestigator	O95153.
GermOnline	ENSG00000005379. Homo sapiens.
Family and domain databases
InterPro	IPR003961. Fibronectin_type3. IPR011511. SH3_2. IPR001452. SH3_domain. [Graphical view]
Pfam	PF07653. SH3_2. 3 hits. [Graphical view]
SMART	SM00060. FN3. 3 hits. SM00326. SH3. 3 hits. [Graphical view]
SUPFAM	SSF49265. FN_III-like. 1 hit. SSF50044. SH3. 3 hits.
PROSITE	PS50853. FN3. 3 hits. PS50002. SH3. 3 hits. [Graphical view]
ProtoNet	Search...
Other
BindingDB	O95153.
ChiTaRS	BZRAP1. human.
GenomeRNAi	9256.
NextBio	34699.
PMAP-CutDB	O95153.
SOURCE	Search...

Entry information

Entry name

RIMB1_HUMAN

Accession

Primary (citable) accession number: O95153
Secondary accession number(s): O75111, Q8N5W3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 16, 2004
Last sequence update:	April 17, 2007
Last modified:	May 1, 2013
This is version 111 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.