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Protein

Battenin

Gene

CLN3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
BatteninUniRule annotation
Gene namesi
Name:CLN3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000188603.16
HGNCiHGNC:2074 CLN3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei44 – 68HelicalUniRule annotationAdd BLAST25
Transmembranei74 – 91HelicalUniRule annotationAdd BLAST18
Transmembranei98 – 122HelicalUniRule annotationAdd BLAST25
Transmembranei179 – 196HelicalUniRule annotationAdd BLAST18
Transmembranei242 – 263HelicalUniRule annotationAdd BLAST22
Transmembranei269 – 288HelicalUniRule annotationAdd BLAST20

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000188603

PTM / Processingi

Proteomic databases

PeptideAtlasiO95086

Expressioni

Gene expression databases

BgeeiENSG00000188603

Family & Domainsi

Sequence similaritiesi

Belongs to the battenin family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000003249
HOGENOMiHOG000164765
HOVERGENiHBG017297

Family and domain databases

InterProiView protein in InterPro
IPR003492 Battenin_disease_Cln3
IPR018460 Battenin_disease_Cln3_subgr
IPR036259 MFS_trans_sf
PANTHERiPTHR10981 PTHR10981, 2 hits
PfamiView protein in Pfam
PF02487 CLN3, 2 hits
PIRSFiPIRSF015974 CLN3_BTN1, 2 hits
PRINTSiPR01315 BATTENIN
SUPFAMiSSF103473 SSF103473, 1 hit

Sequencei

Sequence statusi: Complete.

O95086-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSAAHDILS HKRTSGNQSH VDPGPTPIPH NSSSRFDCNS VSTAAVLLAD
60 70 80 90 100
ILPTLVIKLL APLGLHLLPY SPRVLVSGIC AAGSFVLVAF SHSVGTSLCG
110 120 130 140 150
VVFASISSGL GEVTFLSLTA FYPSYFLLLT SPEAQDPGGE EEAESAARQP
160 170 180 190 200
LIRTEAPESK PGSSSSLSLR ERWTVFKGLL WYIVPLVVVY FAEYFINQGL
210 220 230 240 250
FELLFFWNTS LSHAQQYRWY QMLYQAGVFA SRSSLRCCRI RFTWALALLQ
260 270 280 290 300
CLNLVFLLAD VWFGFLPSIY LVFLIILYEG LLGGAAYVNT FHNIALETSD
310 320 330
EHREFAMAAT CISDTLGISL SGLLALPLHD FLCQLS
Length:336
Mass (Da):36,842
Last modified:May 1, 1999 - v1
Checksum:i8B78EB74349314BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC138894 Genomic DNA No translation available.
AF015595 mRNA Translation: AAD01557.1
UniGeneiHs.534667

Genome annotation databases

EnsembliENST00000636228; ENSP00000489627; ENSG00000188603
UCSCiuc002dpq.2 human

Similar proteinsi

Entry informationi

Entry nameiO95086_HUMAN
AccessioniPrimary (citable) accession number: O95086
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: April 25, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health