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Protein

Protein FAM13A

Gene

FAM13A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GTPase activation

Enzyme and pathway databases

ReactomeiR-HSA-194840. Rho GTPase cycle.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM13A
Gene namesi
Name:FAM13A
Synonyms:FAM13A1, KIAA0914
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

HGNCiHGNC:19367. FAM13A.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

MalaCardsiFAM13A.
Orphaneti2032. Idiopathic pulmonary fibrosis.
PharmGKBiPA164719541.

Polymorphism and mutation databases

BioMutaiFAM13A.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10231023Protein FAM13APRO_0000058920Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei345 – 3451PhosphoserineBy similarity
Modified residuei597 – 5971PhosphoserineBy similarity
Modified residuei617 – 6171PhosphoserineBy similarity
Modified residuei727 – 7271PhosphoserineBy similarity
Modified residuei732 – 7321PhosphothreonineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiO94988.
MaxQBiO94988.
PaxDbiO94988.
PeptideAtlasiO94988.
PRIDEiO94988.

PTM databases

iPTMnetiO94988.
PhosphoSiteiO94988.

Expressioni

Tissue specificityi

Isoform 1 is widely expressed, with highest expression in skeletal muscle, thymus, brain and lung. Isoform 3 is less abundant than isoform 1 and predominantly expressed in kidney, pancreas,liver, lung and thymus.1 Publication

Gene expression databases

BgeeiO94988.
ExpressionAtlasiO94988. baseline and differential.
GenevisibleiO94988. HS.

Organism-specific databases

HPAiHPA038108.
HPA038109.

Interactioni

Protein-protein interaction databases

BioGridi115447. 8 interactions.
IntActiO94988. 6 interactions.
STRINGi9606.ENSP00000264344.

Structurei

3D structure databases

ProteinModelPortaliO94988.
SMRiO94988. Positions 41-231.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini43 – 231189Rho-GAPPROSITE-ProRule annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili666 – 73065Sequence analysisAdd
BLAST
Coiled coili946 – 97833Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the FAM13 family.Curated
Contains 1 Rho-GAP domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG4270. Eukaryota.
ENOG410XRR2. LUCA.
GeneTreeiENSGT00440000037511.
HOGENOMiHOG000112468.
HOVERGENiHBG051529.
InParanoidiO94988.
OMAiRQSKEQD.
OrthoDBiEOG7VDXNT.
PhylomeDBiO94988.
TreeFamiTF328895.

Family and domain databases

Gene3Di1.10.555.10. 1 hit.
InterProiIPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
[Graphical view]
PfamiPF00620. RhoGAP. 1 hit.
[Graphical view]
SMARTiSM00324. RhoGAP. 1 hit.
[Graphical view]
SUPFAMiSSF48350. SSF48350. 1 hit.
PROSITEiPS50238. RHOGAP. 1 hit.
[Graphical view]

Sequences (5)i

Sequence statusi: Complete.

This entry describes 5 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 3 (identifier: O94988-4) [UniParc]FASTAAdd to basket

Also known as: FAM13A1_v2

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MGAGALAICQ SKAAVRLKED MKKIVAVPLN EQKDFTYQKL FGVSLQELER
60 70 80 90 100
QGLTENGIPA VVWNIVEYLT QHGLTQEGLF RVNGNVKVVE QLRLKFESGV
110 120 130 140 150
PVELGKDGDV CSAASLLKLF LRELPDSLIT SALQPRFIQL FQDGRNDVQE
160 170 180 190 200
SSLRDLIKEL PDTHYCLLKY LCQFLTKVAK HHVQNRMNVH NLATVFGPNC
210 220 230 240 250
FHVPPGLEGM KEQDLCNKIM AKILENYNTL FEVEYTENDH LRCENLARLI
260 270 280 290 300
IVKEVYYKNS LPILLTRGLE RDMPKPPPKT KIPKSRSEGS IQAHRVLQPE
310 320 330 340 350
LSDGIPQLSL RLSYRKACLE DMNSAEGAIS AKLVPSSQED ERPLSPFYLS
360 370 380 390 400
AHVPQVSNVS ATGELLERTI RSAVEQHLFD VNNSGGQSSE DSESGTLSAS
410 420 430 440 450
SATSARQRRR QSKEQDEVRH GRDKGLINKE NTPSGFNHLD DCILNTQEVE
460 470 480 490 500
KVHKNTFGCA GERSKPKRQK SSTKLSELHD NQDGLVNMES LNSTRSHERT
510 520 530 540 550
GPDDFEWMSD ERKGNEKDGG HTQHFESPTM KIQEHPSLSD TKQQRNQDAG
560 570 580 590 600
DQEESFVSEV PQSDLTALCD EKNWEEPIPA FSSWQRENSD SDEAHLSPQA
610 620 630 640 650
GRLIRQLLDE DSDPMLSPRF YAYGQSRQYL DDTEVPPSPP NSHSFMRRRS
660 670 680 690 700
SSLGSYDDEQ EDLTPAQLTR RIQSLKKKIR KFEDRFEEEK KYRPSHSDKA
710 720 730 740 750
ANPEVLKWTN DLAKFRRQLK ESKLKISEED LTPRMRQRSN TLPKSFGSQL
760 770 780 790 800
EKEDEKKQEL VDKAIKPSVE ATLESIQRKL QEKRAESSRP EDIKDMTKDQ
810 820 830 840 850
IANEKVALQK ALLYYESIHG RPVTKNERQV MKPLYDRYRL VKQILSRANT
860 870 880 890 900
IPIIGSPSSK RRSPLLQPII EGETASFFKE IKEEEEGSED DSNVKPDFMV
910 920 930 940 950
TLKTDFSARC FLDQFEDDAD GFISPMDDKI PSKCSQDTGL SNLHAASIPE
960 970 980 990 1000
LLEHLQEMRE EKKRIRKKLR DFEDNFFRQN GRNVQKEDRT PMAEEYSEYK
1010 1020
HIKAKLRLLE VLISKRDTDS KSM
Length:1,023
Mass (Da):116,932
Last modified:May 18, 2010 - v2
Checksum:i767AC5A8EC862D68
GO
Isoform 1 (identifier: O94988-1) [UniParc]FASTAAdd to basket

Also known as: FAM13A1_v1

The sequence of this isoform differs from the canonical sequence as follows:
     1-326: Missing.
     327-335: GAISAKLVP → MACEIMPLQ

Show »
Length:697
Mass (Da):80,190
Checksum:iA95CFCDA5C0EEB00
GO
Isoform 2 (identifier: O94988-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-326: Missing.
     327-335: GAISAKLVP → MACEIMPLQ
     855-882: Missing.

Note: No experimental confirmation available.
Show »
Length:669
Mass (Da):77,104
Checksum:i6F72E70FA972482F
GO
Isoform 4 (identifier: O94988-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-340: Missing.
     341-349: ERPLSPFYL → MACEIMPLQ

Note: No experimental confirmation available.
Show »
Length:683
Mass (Da):78,540
Checksum:i02F9B3C086F8FD80
GO
Isoform 5 (identifier: O94988-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-354: Missing.
     355-364: QVSNVSATGE → MACEIMPLQR

Note: No experimental confirmation available.
Show »
Length:669
Mass (Da):77,232
Checksum:i904972533846C861
GO

Sequence cautioni

The sequence BAA74937.3 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence BAC03636.1 differs from that shown.Intron retention.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti509 – 5091S → T in AK027138 (PubMed:14702039).Curated
Sequence conflicti740 – 7401N → Y in BAG59483 (PubMed:14702039).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti769 – 7691V → I.1 Publication
Corresponds to variant rs7657817 [ dbSNP | Ensembl ].
VAR_049019

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 354354Missing in isoform 5. 1 PublicationVSP_039152Add
BLAST
Alternative sequencei1 – 340340Missing in isoform 4. 1 PublicationVSP_039153Add
BLAST
Alternative sequencei1 – 326326Missing in isoform 1 and isoform 2. 2 PublicationsVSP_039154Add
BLAST
Alternative sequencei327 – 3359GAISAKLVP → MACEIMPLQ in isoform 1 and isoform 2. 2 PublicationsVSP_039155
Alternative sequencei341 – 3499ERPLSPFYL → MACEIMPLQ in isoform 4. 1 PublicationVSP_039156
Alternative sequencei355 – 36410QVSNVSATGE → MACEIMPLQR in isoform 5. 1 PublicationVSP_039157
Alternative sequencei855 – 88228Missing in isoform 2. 2 PublicationsVSP_039158Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB020721 mRNA. Translation: BAA74937.3. Different initiation.
AK027138 mRNA. No translation available.
AK091328 mRNA. Translation: BAC03636.1. Sequence problems.
AK296932 mRNA. Translation: BAG59483.1.
AC108065 Genomic DNA. No translation available.
AC021183 Genomic DNA. No translation available.
BC086875 mRNA. Translation: AAH86875.1.
BN000265 mRNA. Translation: CAE18110.1.
CCDSiCCDS34029.1. [O94988-4]
CCDS43251.1. [O94988-1]
CCDS58911.1. [O94988-6]
CCDS58912.1. [O94988-5]
CCDS58913.1. [O94988-3]
RefSeqiNP_001015045.1. NM_001015045.2. [O94988-1]
NP_001252507.1. NM_001265578.1. [O94988-5]
NP_001252508.1. NM_001265579.1. [O94988-3]
NP_001252509.1. NM_001265580.1. [O94988-6]
NP_055698.2. NM_014883.3. [O94988-4]
XP_011529818.1. XM_011531516.1. [O94988-4]
UniGeneiHs.714536.
Hs.97270.

Genome annotation databases

EnsembliENST00000264344; ENSP00000264344; ENSG00000138640. [O94988-4]
ENST00000395002; ENSP00000378450; ENSG00000138640. [O94988-3]
ENST00000503556; ENSP00000427189; ENSG00000138640. [O94988-5]
ENST00000508369; ENSP00000421562; ENSG00000138640. [O94988-1]
ENST00000513837; ENSP00000423252; ENSG00000138640. [O94988-6]
GeneIDi10144.
KEGGihsa:10144.
UCSCiuc003hsb.3. human. [O94988-4]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB020721 mRNA. Translation: BAA74937.3. Different initiation.
AK027138 mRNA. No translation available.
AK091328 mRNA. Translation: BAC03636.1. Sequence problems.
AK296932 mRNA. Translation: BAG59483.1.
AC108065 Genomic DNA. No translation available.
AC021183 Genomic DNA. No translation available.
BC086875 mRNA. Translation: AAH86875.1.
BN000265 mRNA. Translation: CAE18110.1.
CCDSiCCDS34029.1. [O94988-4]
CCDS43251.1. [O94988-1]
CCDS58911.1. [O94988-6]
CCDS58912.1. [O94988-5]
CCDS58913.1. [O94988-3]
RefSeqiNP_001015045.1. NM_001015045.2. [O94988-1]
NP_001252507.1. NM_001265578.1. [O94988-5]
NP_001252508.1. NM_001265579.1. [O94988-3]
NP_001252509.1. NM_001265580.1. [O94988-6]
NP_055698.2. NM_014883.3. [O94988-4]
XP_011529818.1. XM_011531516.1. [O94988-4]
UniGeneiHs.714536.
Hs.97270.

3D structure databases

ProteinModelPortaliO94988.
SMRiO94988. Positions 41-231.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi115447. 8 interactions.
IntActiO94988. 6 interactions.
STRINGi9606.ENSP00000264344.

PTM databases

iPTMnetiO94988.
PhosphoSiteiO94988.

Polymorphism and mutation databases

BioMutaiFAM13A.

Proteomic databases

EPDiO94988.
MaxQBiO94988.
PaxDbiO94988.
PeptideAtlasiO94988.
PRIDEiO94988.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000264344; ENSP00000264344; ENSG00000138640. [O94988-4]
ENST00000395002; ENSP00000378450; ENSG00000138640. [O94988-3]
ENST00000503556; ENSP00000427189; ENSG00000138640. [O94988-5]
ENST00000508369; ENSP00000421562; ENSG00000138640. [O94988-1]
ENST00000513837; ENSP00000423252; ENSG00000138640. [O94988-6]
GeneIDi10144.
KEGGihsa:10144.
UCSCiuc003hsb.3. human. [O94988-4]

Organism-specific databases

CTDi10144.
GeneCardsiFAM13A.
H-InvDBHIX0004368.
HGNCiHGNC:19367. FAM13A.
HPAiHPA038108.
HPA038109.
MalaCardsiFAM13A.
MIMi613299. gene.
neXtProtiNX_O94988.
Orphaneti2032. Idiopathic pulmonary fibrosis.
PharmGKBiPA164719541.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4270. Eukaryota.
ENOG410XRR2. LUCA.
GeneTreeiENSGT00440000037511.
HOGENOMiHOG000112468.
HOVERGENiHBG051529.
InParanoidiO94988.
OMAiRQSKEQD.
OrthoDBiEOG7VDXNT.
PhylomeDBiO94988.
TreeFamiTF328895.

Enzyme and pathway databases

ReactomeiR-HSA-194840. Rho GTPase cycle.

Miscellaneous databases

ChiTaRSiFAM13A. human.
GeneWikiiFamily_with_sequence_similarity_13,_member_A1.
GenomeRNAii10144.
PROiO94988.
SOURCEiSearch...

Gene expression databases

BgeeiO94988.
ExpressionAtlasiO94988. baseline and differential.
GenevisibleiO94988. HS.

Family and domain databases

Gene3Di1.10.555.10. 1 hit.
InterProiIPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
[Graphical view]
PfamiPF00620. RhoGAP. 1 hit.
[Graphical view]
SMARTiSM00324. RhoGAP. 1 hit.
[Graphical view]
SUPFAMiSSF48350. SSF48350. 1 hit.
PROSITEiPS50238. RHOGAP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
    Nagase T., Ishikawa K., Suyama M., Kikuno R., Hirosawa M., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
    DNA Res. 5:355-364(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Spleen.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 5), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 526-1023 (ISOFORM 2).
    Tissue: Fetal brain, Ileal mucosa and Tongue.
  3. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4), VARIANT ILE-769.
    Tissue: Chondrosarcoma.
  5. "Cloning and characterization of FAM13A1--a gene near a milk protein QTL on BTA6: evidence for population-wide linkage disequilibrium in Israeli Holsteins."
    Cohen M., Reichenstein M., Everts-van der Wind A., Heon-Lee J., Shani M., Lewin H.A., Weller J.I., Ron M., Seroussi E.
    Genomics 84:374-383(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION (ISOFORM 3), TISSUE SPECIFICITY.
  6. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
    Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R., Greff Z., Keri G., Stemmann O., Mann M.
    Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-732, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  7. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  8. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  9. "Toward a comprehensive characterization of a human cancer cell phosphoproteome."
    Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., Mohammed S.
    J. Proteome Res. 12:260-271(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma and Erythroleukemia.

Entry informationi

Entry nameiFA13A_HUMAN
AccessioniPrimary (citable) accession number: O94988
Secondary accession number(s): B4DLC1
, Q24JP0, Q5PR21, Q8NBA3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 11, 2003
Last sequence update: May 18, 2010
Last modified: July 6, 2016
This is version 123 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.