O94964 (K0889_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein KIAA0889

Gene names

Name:	KIAA0889
Synonyms:	C20orf117

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1423 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence caution

The sequence BAA74912.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing Polymorphism
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: O94964-1) This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: O94964-2) The sequence of this isoform differs from the canonical sequence as follows:      1-1: M → MEAPAAEPPV...DEIEELRAEM
Note: No experimental confirmation available. Gene prediction based on EST data.
Isoform 3 (identifier: O94964-3) The sequence of this isoform differs from the canonical sequence as follows:      1-870: Missing.      871-922: NRLSQLQKAA...EVELGGNGLK → MWDWAPTTSL...NNDVSSSVLR      1374-1423: DAVCDCSTQSLTSCFARSSRSAIRHSPSKCRLHPSESSWGGEERALPPSE → VGGWDLSFLLVGGVSI
Isoform 4 (identifier: O94964-4) The sequence of this isoform differs from the canonical sequence as follows:      998-1016: RQMQRSYTAPDKTGIRVYY → SQKLPFLLILAPPQPPPIL      1017-1423: Missing.
Sequence annotation (Features)
	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
	Sequence conflict	998	1	S → R in BAC86621. Ref.2

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1423	1423	Uncharacterized protein KIAA0889		PRO_0000050781
Amino acid modifications
	Modified residue	1017	1	Phosphoserine Ref.5 Ref.7
	Modified residue	1244	1	Phosphoserine Ref.6
	Modified residue	1303	1	Phosphoserine Ref.6
Natural variations
	Alternative sequence	1 – 870	870	Missing in isoform 3.		VSP_035976
	Alternative sequence	1	1	M → MEAPAAEPPVRGCGPQPAPA PAPAPERKKSHRAPSPARPK DVAGWSLAKGRRGPGPGSAV ACSAAFSSRPDKKGRAVAPG ARGAGVRVAGVRTGVRAKGR PRSGAGPRPPPPPPSLTDSS SEVSDCASEEARLLGLELAL SSDAESAAGGPAGVRTGQPA QPAPSAQQPPRPPASPDEPS VAASSVGSSRLPLSASLAFS DLTEEMLDCGPSGLVRELEE LRSENDYLKDEIEELRAEM in isoform 2.		VSP_035977
	Alternative sequence	871 – 922	52	NRLSQ…GNGLK → MWDWAPTTSLQEVNKTVLVF ALTQHTDQGGRPECALSVIS TNNDVSSSVLR in isoform 3.		VSP_035978
	Alternative sequence	998 – 1016	19	RQMQR…IRVYY → SQKLPFLLILAPPQPPPIL in isoform 4.		VSP_040825
	Alternative sequence	1017 – 1423	407	Missing in isoform 4.		VSP_040826
	Alternative sequence	1374 – 1423	50	DAVCD…LPPSE → VGGWDLSFLLVGGVSI in isoform 3.		VSP_035979
	Natural variant	993	1	Q → H. Corresponds to variant rs34459518 [ dbSNP | Ensembl ].		VAR_056848

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified December 16, 2008. Version 2. Checksum: EE50F4D144ABD972	FASTA	1,423	159,760
	10 20 30 40 50 60 MLEMRDVYME EDVYQLQELR QQLDQASKTC RILQYRLRKA ERRSLRAAQT GQVDGELIRG 70 80 90 100 110 120 LEQDVKVSKD ISMRLHKELE VVEKKRARLE EENEELRQRL IETELAKQVL QTELERPREH 130 140 150 160 170 180 SLKKRGTRSL GKADKKTLVQ EDSADLKCQL HFAKEESALM CKKLTKLAKE NDSMKEELLK 190 200 210 220 230 240 YRSLYGDLDS ALSAEELADA PHSRETELKV HLKLVEEEAN LLSRRIVELE VENRGLRAEM 250 260 270 280 290 300 DDMKDHGGGC GGPEARLAFS ALGGGECGES LAELRRHLQF VEEEAELLRR SSAELEDQNK 310 320 330 340 350 360 LLLNELAKFR SEHELDVALS EDSCSVLSEP SQEELAAAKL QIGELSGKVK KLQYENRVLL 370 380 390 400 410 420 SNLQRCDLAS CQSTRPMLET DAEAGDSAQC VPAPLGETHE SHAVRLCRAR EAEVLPGLRE 430 440 450 460 470 480 QAALVSKAID VLVADANGFT AGLRLCLDNE CADFRLHEAP DNSEGPRDTK LIHAILVRLS 490 500 510 520 530 540 VLQQELNAFT RKADAVLGCS VKEQQESFSS LPPLGSQGLS KEILLAKDLG SDFQPPDFRD 550 560 570 580 590 600 LPEWEPRIRE AFRTGDLDSK PDPSRSFRPY RAEDNDSYAS EIKELQLVLA EAHDSLRGLQ 610 620 630 640 650 660 EQLSQERQLR KEEADNFNQK MVQLKEDQQR ALLRREFELQ SLSLQRRLEQ KFWSQEKNML 670 680 690 700 710 720 VQESQQFKHN FLLLFMKLRW FLKRWRQGKV LPSEGDDFLE VNSMKELYLL MEEEEINAQH 730 740 750 760 770 780 SDNKACTGDS WTQNTPNEYI KTLADMKVTL KELCWLLRDE RRGLTELQQQ FAKAKATWET 790 800 810 820 830 840 ERAELKGHTS QMELKTGKGA GERAGPDWKA ALQREREEQQ HLLAESYSAV MELTRQLQIS 850 860 870 880 890 900 ERNWSQEKLQ LVERLQGEKQ QVEQQVKELQ NRLSQLQKAA DPWVLKHSEL EKQDNSWKET 910 920 930 940 950 960 RSEKIHDKEA VSEVELGGNG LKRTKSVSSM SEFESLLDCS PYLAGGDARG KKLPNNPAFG 970 980 990 1000 1010 1020 FVSSEPGDPE KDTKEKPGLS SRDCNHLGAL ACQDPPGRQM QRSYTAPDKT GIRVYYSPPV 1030 1040 1050 1060 1070 1080 ARRLGVPVVH DKEGKIIIEP GFLFTTAKPK ESAEADGLAE SSYGRWLCNF SRQRLDGGSA 1090 1100 1110 1120 1130 1140 GSPSAAGPGF PAALHDFEMS GNMSDDMKEI TNCVRQAMRS GSLERKVKST SSQTVGLASV 1150 1160 1170 1180 1190 1200 GTQTIRTVSV GLQTDPPRSS LHGKAWSPRS SSLVSVRSKQ ISSSLDKVHS RIERPCCSPK 1210 1220 1230 1240 1250 1260 YGSPKLQRRS VSKLDSSKDR SLWNLHQGKQ NGSAWARSTT TRDSPVLRNI NDGLSSLFSV 1270 1280 1290 1300 1310 1320 VEHSGSTESV WKLGMSETRA KPEPPKYGIV QEFFRNVCGR APSPTSSAGE EGTKKPEPLS 1330 1340 1350 1360 1370 1380 PASYHQPEGV ARILNKKAAK LGSSEEVRLT MLPQVGKDGV LRDGDGAVVL PNEDAVCDCS 1390 1400 1410 1420 TQSLTSCFAR SSRSAIRHSP SKCRLHPSES SWGGEERALP PSE
	Isoform 2 [UniParc]. Checksum: 95230B6E556F3D03	FASTA	1,661	183,858
	10 20 30 40 50 60 MEAPAAEPPV RGCGPQPAPA PAPAPERKKS HRAPSPARPK DVAGWSLAKG RRGPGPGSAV 70 80 90 100 110 120 ACSAAFSSRP DKKGRAVAPG ARGAGVRVAG VRTGVRAKGR PRSGAGPRPP PPPPSLTDSS 130 140 150 160 170 180 SEVSDCASEE ARLLGLELAL SSDAESAAGG PAGVRTGQPA QPAPSAQQPP RPPASPDEPS 190 200 210 220 230 240 VAASSVGSSR LPLSASLAFS DLTEEMLDCG PSGLVRELEE LRSENDYLKD EIEELRAEML 250 260 270 280 290 300 EMRDVYMEED VYQLQELRQQ LDQASKTCRI LQYRLRKAER RSLRAAQTGQ VDGELIRGLE 310 320 330 340 350 360 QDVKVSKDIS MRLHKELEVV EKKRARLEEE NEELRQRLIE TELAKQVLQT ELERPREHSL 370 380 390 400 410 420 KKRGTRSLGK ADKKTLVQED SADLKCQLHF AKEESALMCK KLTKLAKEND SMKEELLKYR 430 440 450 460 470 480 SLYGDLDSAL SAEELADAPH SRETELKVHL KLVEEEANLL SRRIVELEVE NRGLRAEMDD 490 500 510 520 530 540 MKDHGGGCGG PEARLAFSAL GGGECGESLA ELRRHLQFVE EEAELLRRSS AELEDQNKLL 550 560 570 580 590 600 LNELAKFRSE HELDVALSED SCSVLSEPSQ EELAAAKLQI GELSGKVKKL QYENRVLLSN 610 620 630 640 650 660 LQRCDLASCQ STRPMLETDA EAGDSAQCVP APLGETHESH AVRLCRAREA EVLPGLREQA 670 680 690 700 710 720 ALVSKAIDVL VADANGFTAG LRLCLDNECA DFRLHEAPDN SEGPRDTKLI HAILVRLSVL 730 740 750 760 770 780 QQELNAFTRK ADAVLGCSVK EQQESFSSLP PLGSQGLSKE ILLAKDLGSD FQPPDFRDLP 790 800 810 820 830 840 EWEPRIREAF RTGDLDSKPD PSRSFRPYRA EDNDSYASEI KELQLVLAEA HDSLRGLQEQ 850 860 870 880 890 900 LSQERQLRKE EADNFNQKMV QLKEDQQRAL LRREFELQSL SLQRRLEQKF WSQEKNMLVQ 910 920 930 940 950 960 ESQQFKHNFL LLFMKLRWFL KRWRQGKVLP SEGDDFLEVN SMKELYLLME EEEINAQHSD 970 980 990 1000 1010 1020 NKACTGDSWT QNTPNEYIKT LADMKVTLKE LCWLLRDERR GLTELQQQFA KAKATWETER 1030 1040 1050 1060 1070 1080 AELKGHTSQM ELKTGKGAGE RAGPDWKAAL QREREEQQHL LAESYSAVME LTRQLQISER 1090 1100 1110 1120 1130 1140 NWSQEKLQLV ERLQGEKQQV EQQVKELQNR LSQLQKAADP WVLKHSELEK QDNSWKETRS 1150 1160 1170 1180 1190 1200 EKIHDKEAVS EVELGGNGLK RTKSVSSMSE FESLLDCSPY LAGGDARGKK LPNNPAFGFV 1210 1220 1230 1240 1250 1260 SSEPGDPEKD TKEKPGLSSR DCNHLGALAC QDPPGRQMQR SYTAPDKTGI RVYYSPPVAR 1270 1280 1290 1300 1310 1320 RLGVPVVHDK EGKIIIEPGF LFTTAKPKES AEADGLAESS YGRWLCNFSR QRLDGGSAGS 1330 1340 1350 1360 1370 1380 PSAAGPGFPA ALHDFEMSGN MSDDMKEITN CVRQAMRSGS LERKVKSTSS QTVGLASVGT 1390 1400 1410 1420 1430 1440 QTIRTVSVGL QTDPPRSSLH GKAWSPRSSS LVSVRSKQIS SSLDKVHSRI ERPCCSPKYG 1450 1460 1470 1480 1490 1500 SPKLQRRSVS KLDSSKDRSL WNLHQGKQNG SAWARSTTTR DSPVLRNIND GLSSLFSVVE 1510 1520 1530 1540 1550 1560 HSGSTESVWK LGMSETRAKP EPPKYGIVQE FFRNVCGRAP SPTSSAGEEG TKKPEPLSPA 1570 1580 1590 1600 1610 1620 SYHQPEGVAR ILNKKAAKLG SSEEVRLTML PQVGKDGVLR DGDGAVVLPN EDAVCDCSTQ 1630 1640 1650 1660 SLTSCFARSS RSAIRHSPSK CRLHPSESSW GGEERALPPS E
	Isoform 3 [UniParc]. Checksum: 9F9141EDD1CC6005	FASTA	518	55,761
	10 20 30 40 50 60 MWDWAPTTSL QEVNKTVLVF ALTQHTDQGG RPECALSVIS TNNDVSSSVL RRTKSVSSMS 70 80 90 100 110 120 EFESLLDCSP YLAGGDARGK KLPNNPAFGF VSSEPGDPEK DTKEKPGLSS RDCNHLGALA 130 140 150 160 170 180 CQDPPGRQMQ RSYTAPDKTG IRVYYSPPVA RRLGVPVVHD KEGKIIIEPG FLFTTAKPKE 190 200 210 220 230 240 SAEADGLAES SYGRWLCNFS RQRLDGGSAG SPSAAGPGFP AALHDFEMSG NMSDDMKEIT 250 260 270 280 290 300 NCVRQAMRSG SLERKVKSTS SQTVGLASVG TQTIRTVSVG LQTDPPRSSL HGKAWSPRSS 310 320 330 340 350 360 SLVSVRSKQI SSSLDKVHSR IERPCCSPKY GSPKLQRRSV SKLDSSKDRS LWNLHQGKQN 370 380 390 400 410 420 GSAWARSTTT RDSPVLRNIN DGLSSLFSVV EHSGSTESVW KLGMSETRAK PEPPKYGIVQ 430 440 450 460 470 480 EFFRNVCGRA PSPTSSAGEE GTKKPEPLSP ASYHQPEGVA RILNKKAAKL GSSEEVRLTM 490 500 510 LPQVGKDGVL RDGDGAVVLP NEVGGWDLSF LLVGGVSI
	Isoform 4 [UniParc]. Checksum: 34E50D41691F15ED	FASTA	1,016	115,758
	10 20 30 40 50 60 MLEMRDVYME EDVYQLQELR QQLDQASKTC RILQYRLRKA ERRSLRAAQT GQVDGELIRG 70 80 90 100 110 120 LEQDVKVSKD ISMRLHKELE VVEKKRARLE EENEELRQRL IETELAKQVL QTELERPREH 130 140 150 160 170 180 SLKKRGTRSL GKADKKTLVQ EDSADLKCQL HFAKEESALM CKKLTKLAKE NDSMKEELLK 190 200 210 220 230 240 YRSLYGDLDS ALSAEELADA PHSRETELKV HLKLVEEEAN LLSRRIVELE VENRGLRAEM 250 260 270 280 290 300 DDMKDHGGGC GGPEARLAFS ALGGGECGES LAELRRHLQF VEEEAELLRR SSAELEDQNK 310 320 330 340 350 360 LLLNELAKFR SEHELDVALS EDSCSVLSEP SQEELAAAKL QIGELSGKVK KLQYENRVLL 370 380 390 400 410 420 SNLQRCDLAS CQSTRPMLET DAEAGDSAQC VPAPLGETHE SHAVRLCRAR EAEVLPGLRE 430 440 450 460 470 480 QAALVSKAID VLVADANGFT AGLRLCLDNE CADFRLHEAP DNSEGPRDTK LIHAILVRLS 490 500 510 520 530 540 VLQQELNAFT RKADAVLGCS VKEQQESFSS LPPLGSQGLS KEILLAKDLG SDFQPPDFRD 550 560 570 580 590 600 LPEWEPRIRE AFRTGDLDSK PDPSRSFRPY RAEDNDSYAS EIKELQLVLA EAHDSLRGLQ 610 620 630 640 650 660 EQLSQERQLR KEEADNFNQK MVQLKEDQQR ALLRREFELQ SLSLQRRLEQ KFWSQEKNML 670 680 690 700 710 720 VQESQQFKHN FLLLFMKLRW FLKRWRQGKV LPSEGDDFLE VNSMKELYLL MEEEEINAQH 730 740 750 760 770 780 SDNKACTGDS WTQNTPNEYI KTLADMKVTL KELCWLLRDE RRGLTELQQQ FAKAKATWET 790 800 810 820 830 840 ERAELKGHTS QMELKTGKGA GERAGPDWKA ALQREREEQQ HLLAESYSAV MELTRQLQIS 850 860 870 880 890 900 ERNWSQEKLQ LVERLQGEKQ QVEQQVKELQ NRLSQLQKAA DPWVLKHSEL EKQDNSWKET 910 920 930 940 950 960 RSEKIHDKEA VSEVELGGNG LKRTKSVSSM SEFESLLDCS PYLAGGDARG KKLPNNPAFG 970 980 990 1000 1010 FVSSEPGDPE KDTKEKPGLS SRDCNHLGAL ACQDPPGSQK LPFLLILAPP QPPPIL

References

[1]	"Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." Nagase T., Ishikawa K., Suyama M., Kikuno R., Hirosawa M., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O. DNA Res. 5:355-364(1998) [PubMed: 10048485] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3). Tissue: Brain.
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3 AND 4). Tissue: Cerebellum and Embryo.
[3]	"The DNA sequence and comparative analysis of human chromosome 20." Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E. , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J. Nature 414:865-871(2001) [PubMed: 11780052] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3). Tissue: Brain.
[5]	"Large-scale characterization of HeLa cell nuclear phosphoproteins." Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J., Li J., Cohn M.A., Cantley L.C., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004) [PubMed: 15302935] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1017, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[6]	"Evaluation of the low-specificity protease elastase for large-scale phosphoproteome analysis." Wang B., Malik R., Nigg E.A., Korner R. Anal. Chem. 80:9526-9533(2008) [PubMed: 19007248] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1244 AND SER-1303, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[7]	"A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed: 18669648] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1017, MASS SPECTROMETRY. Tissue: Cervix carcinoma.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB020696 mRNA. Translation: BAA74912.2. Different initiation. AK022023 mRNA. Translation: BAB13954.1. AK126630 mRNA. Translation: BAC86621.1. AL391602, AL079335, AL132768 Genomic DNA. Translation: CAI12788.3. AL132768, AL079335, AL391602 Genomic DNA. Translation: CAI21460.3. AL079335, AL132768, AL391602 Genomic DNA. Translation: CAI42289.3. BC113405 mRNA. Translation: AAI13406.1. BC113433 mRNA. Translation: AAI13434.1.
IPI	IPI00022274. IPI00797771. IPI00915294. IPI00942898.
RefSeq	NP_542194.2. NM_080627.2. NP_954650.2. NM_199181.2.
UniGene	Hs.460807.
3D structure databases
ProteinModelPortal	O94964.
ModBase	Search...
Protein-protein interaction databases
IntAct	O94964. 3 interactions.
PTM databases
PhosphoSite	O94964.
2D gel databases
UCD-2DPAGE	O94964.
Proteomic databases
PeptideAtlas	O94964.
PRIDE	O94964.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000237536; ENSP00000237536; ENSG00000149639. ENST00000279034; ENSP00000279034; ENSG00000149639. ENST00000357779; ENSP00000350424; ENSG00000149639. ENST00000456801; ENSP00000413886; ENSG00000149639.
GeneID	140710.
KEGG	hsa:140710.
Organism-specific databases
CTD	140710.
GeneCards	GC20M035406.
HGNC	HGNC:16111. KIAA0889.
neXtProt	NX_O94964.
PharmGKB	PA25657.
HUGE	Search...
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG09044.
GeneTree	ENSGT00530000063889.
HOGENOM	HBG716993.
HOVERGEN	HBG080205.
OMA	SDNKACT.
OrthoDB	EOG4XSKP1.
Gene expression databases
ArrayExpress	O94964.
Bgee	O94964.
CleanEx	HS_C20orf117.
Genevestigator	O94964.
GermOnline	ENSG00000149639. Homo sapiens.
Family and domain databases
InterPro	IPR021507. DUF3166. [Graphical view]
Pfam	PF11365. DUF3166. 2 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	84283.

Entry information

Entry name

K0889_HUMAN

Accession

Primary (citable) accession number: O94964
Secondary accession number(s): A6NK10 , Q14DB2, Q5JW51, Q6ZTG8

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 25, 2002
Last sequence update:	December 16, 2008
Last modified:	January 25, 2012
This is version 79 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.