O94875 (SRBS2_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sorbin and SH3 domain-containing protein 2

Alternative name(s):
Arg/Abl-interacting protein 2
Short name=ArgBP2
Sorbin

Gene names

Name:	SORBS2
Synonyms:	ARGBP2, KIAA0777

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1100 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder. Ref.1 Ref.9
Subunit structure	Interacts with ABL, CBL, DNM1, DNM2, FLOT1, MLLT4/afadin, PTK2B/PYK2, SAPAP, SPTAN1, SYNJ1, SYNJ2, VCL/vinculin, and WASF By similarity. Interacts with ABL1/c-Abl, ABL2/v-Abl/Arg, ACTN, AKT1, CBL, PALLD and PAK1. Ref.1 Ref.9 Ref.10 Ref.11
Subcellular location	Cytoplasm › perinuclear region. Note: Found at the Z-disk sarcomeres, stress fibers, dense bodies and focal adhesion. Ref.1 Ref.10
Tissue specificity	Abundantly expressed in heart. In cardiac muscle cells, located in the Z-disks of sarcomere. Also found, but to a lower extent, in small and large intestine, pancreas, thymus, colon, spleen, prostate, testis, brain, ovary and epithelial cells. Ref.1 Ref.2
Post-translational modification	Ubiquitinated by CBL. Ref.9 Ref.11
Sequence similarities	Contains 3 SH3 domains. Contains 1 SoHo domain.
Sequence caution	The sequence BAA34497.2 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Cellular component	Cytoplasm
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Repeat SH3 domain
PTM	Amidation Phosphoprotein Ubl conjugation
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	Z disc Non-traceable author statement Ref.1. Source: UniProtKB actin cytoskeleton Traceable author statement Ref.1. Source: ProtInc nucleus Non-traceable author statement Ref.1. Source: UniProtKB perinuclear region of cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	cytoskeletal adaptor activity Traceable author statement Ref.1. Source: ProtInc structural constituent of cytoskeleton Traceable author statement Ref.1. Source: ProtInc structural constituent of muscle Traceable author statement Ref.1. Source: ProtInc zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 10 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: O94875-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: O94875-2)

Also known as: ArgBP2a;

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MNTGRDSQSPDSAKGFRSVRPNLQDKRSPTQSQITVNGNSGGAVSPM
     228-228: P → PTDRINPDDIDLENEPWYKFFSELEFGRPPPKKPLDYVQDHSSGVFNE
     308-834: Missing.

Isoform 3 (identifier: O94875-3)

The sequence of this isoform differs from the canonical sequence as follows:
     228-228: P → PPPLPTTPTPVPREPGRKPLSSSRLGEVTGSPSPPPRSGAPTPSSRAPALSPTRPPKKPLDYVQDHSSGVFNE
     308-834: Missing.

Note: Contains a phosphoserine at position 258. Contains a phosphoserine at position 260.

Isoform 4 (identifier: O94875-4)

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MNTGRDSQSPDSAKGFRSVRPNLQDKRSPTQSQITVNGNSGGAVSPM
     228-228: P → PPPLPTTPTPVPREPGRKPLSSSRLGEVTGSPSPPPRSGAPTPSSRAPALSPTRPPKKPLDYVQDHSSGVFNE
     308-834: Missing.

Note: Contains a phosphoserine at position 304. Contains a phosphoserine at position 306.

Isoform 5 (identifier: O94875-5)

Also known as: ArgBP2b;

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MNTGRDSQSPDSAKGFRSVRPNLQDKRSPTQSQITVNGNSGGAVSPM
     228-228: P → PPPLPTTPTPVPREPGRKPLSSSRLGEVTGSPSPPPRSGAPTPSSRAPALSPTRPPKKPLDYVQDHSSGVFNE
     308-834: Missing.
     1050-1100: YNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL → GYTLT

Note: Contains a phosphoserine at position 304. Contains a phosphoserine at position 306.

Isoform 6 (identifier: O94875-6)

Also known as: Sorbin;

The sequence of this isoform differs from the canonical sequence as follows:
     1-81: Missing.
     82-89: GIPTAIRT → MKATTPLQ
     229-237: ASLYQSSID → VSKPQAGRR
     238-1100: Missing.

Note: Contains a alanine amide at position 153.

Isoform 7 (identifier: O94875-7)

The sequence of this isoform differs from the canonical sequence as follows:
     1-89: MSYYQRPFSP...ESGIPTAIRT → MKATTPLQ
     112-126: Missing.

Note: No experimental confirmation available.

Isoform 8 (identifier: O94875-8)

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MNTGRDSQSPDSAWRSYNDGNQETLNGDATYSSLAAKGFRSVRPNLQDKRSPTQSQITVNGNSGGAVSPM
     228-228: P → PPPKKPLDYVQDHSSGVFNE
     308-834: Missing.

Note: No experimental confirmation available.

Isoform 9 (identifier: O94875-9)

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MSVTLTSVKR...GNSGGAVSPM
     112-126: Missing.
     308-834: Missing.

Note: No experimental confirmation available.

Isoform 10 (identifier: O94875-10)

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MYSNEDSRQT...GNSGGAVSPM
     228-228: P → PPPLPTTPTPVPREPGRKPLSSSRLGEVTGSPSPPPRSGAPTPSSRAPALSPTRPPKKPLDYVQDHSSGVFNE
     308-834: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1100	1100	Sorbin and SH3 domain-containing protein 2		PRO_0000344477
Regions
	Domain	66 – 127	62	SoHo
	Domain	863 – 922	60	SH3 1
	Domain	938 – 999	62	SH3 2
	Domain	1041 – 1100	60	SH3 3
	Compositional bias	167 – 182	16	Pro-rich
	Compositional bias	640 – 652	13	His-rich
	Compositional bias	931 – 934	4	Poly-Pro
Amino acid modifications
	Modified residue	30	1	Phosphoserine By similarity
	Modified residue	154	1	Phosphoserine By similarity
	Modified residue	157	1	Phosphoserine Ref.12 Ref.13
	Modified residue	259	1	Phosphoserine By similarity
	Modified residue	277	1	Phosphothreonine Ref.12
	Modified residue	278	1	Phosphoserine By similarity
	Modified residue	298	1	Phosphoserine Ref.13
	Modified residue	299	1	Phosphoserine Ref.13
	Modified residue	301	1	Phosphoserine Ref.12
	Modified residue	302	1	Phosphoserine Ref.12 Ref.13
	Modified residue	371	1	Phosphothreonine By similarity
	Modified residue	376	1	Phosphoserine By similarity
	Modified residue	750	1	Phosphoserine By similarity
	Modified residue	1017	1	Phosphoserine By similarity
	Modified residue	1018	1	Phosphoserine By similarity
Natural variations
	Alternative sequence	1 – 89	89	MSYYQ…TAIRT → MKATTPLQ in isoform 7.		VSP_043665
	Alternative sequence	1 – 81	81	Missing in isoform 6.		VSP_034791
	Alternative sequence	1	1	M → MYSNEDSRQTIVYSEESNTT MSYTQKITNPLPAASSTDPA PFANINTPVLQEDYRQDSQT RRISTLKLTHNQDLGSSSPI STPQFSKSVEVPSFLKRPRS LTPNPVPETHTASLSIQIAP LSGQDLESHKQLPELSPETA KIPLQQERQKSAVAAASQSS DCRVSQITVNGNSGGAVSPM in isoform 10.		VSP_046220
	Alternative sequence	1	1	M → MNTGRDSQSPDSAKGFRSVR PNLQDKRSPTQSQITVNGNS GGAVSPM in isoform 2, isoform 4 and isoform 5.		VSP_034792
	Alternative sequence	1	1	M → MNTGRDSQSPDSAWRSYNDG NQETLNGDATYSSLAAKGFR SVRPNLQDKRSPTQSQITVN GNSGGAVSPM in isoform 8.		VSP_045640
	Alternative sequence	1	1	M → MSVTLTSVKRVQSSPNLLAA GRDSQSPDSAWRSYNDGNQE TLNGDATYSSLAAKGFRSVR PNLQDKRSPTQSQITVNGNS GGAVSPM in isoform 9.		VSP_046219
	Alternative sequence	82 – 89	8	GIPTAIRT → MKATTPLQ in isoform 6.		VSP_034793
	Alternative sequence	112 – 126	15	Missing in isoform 7 and isoform 9.		VSP_043666
	Alternative sequence	228	1	P → PTDRINPDDIDLENEPWYKF FSELEFGRPPPKKPLDYVQD HSSGVFNE in isoform 2.		VSP_034794
	Alternative sequence	228	1	P → PPPLPTTPTPVPREPGRKPL SSSRLGEVTGSPSPPPRSGA PTPSSRAPALSPTRPPKKPL DYVQDHSSGVFNE in isoform 3, isoform 4, isoform 5 and isoform 10.		VSP_034795
	Alternative sequence	228	1	P → PPPKKPLDYVQDHSSGVFNE in isoform 8.		VSP_045641
	Alternative sequence	229 – 237	9	ASLYQSSID → VSKPQAGRR in isoform 6.		VSP_034796
	Alternative sequence	238 – 1100	863	Missing in isoform 6.		VSP_034797
	Alternative sequence	308 – 834	527	Missing in isoform 2, isoform 3, isoform 4, isoform 5, isoform 8, isoform 9 and isoform 10.		VSP_034798
	Alternative sequence	1050 – 1100	51	YNYTP…YVKRL → GYTLT in isoform 5.		VSP_034799
	Natural variant	1048	1	A → V. Corresponds to variant rs725185 [ dbSNP | Ensembl ].		VAR_045624
Experimental info
	Sequence conflict	73	1	P → L in AK225327. Ref.5
	Sequence conflict	206	1	R → Q in AK225327. Ref.5
	Sequence conflict	1034	1	F → L in BAH11501. Ref.4
Isoform 2:
	Sequence conflict	13	1	A → P in AAC05509. Ref.1
Isoform 5:
	Sequence conflict	13	1	A → P in AAC05508. Ref.1
Isoform 10:
	Sequence conflict	424	1	K → E in AK225812. Ref.5

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified July 22, 2008. Version 3. Checksum: 7E98B196D4DB38E6	FASTA	1,100	124,108
	10 20 30 40 50 60 MSYYQRPFSP SAYSLPASLN SSIVMQHGTS LDSTDTYPQH AQSLDGTTSS SIPLYRSSEE 70 80 90 100 110 120 EKRVTVIKAP HYPGIGPVDE SGIPTAIRTT VDRPKDWYKT MFKQIHMVHK PDDDTDMYNT 130 140 150 160 170 180 PYTYNAGLYN PPYSAQSHPA AKTQTYRPLS KSHSDNSPNA FKDASSPVPP PHVPPPVPPL 190 200 210 220 230 240 RPRDRSSTEK HDWDPPDRKV DTRKFRSEPR SIFEYEPGKS SILQHERPAS LYQSSIDRSL 250 260 270 280 290 300 ERPMSSASMA SDFRKRRKSE PAVGPPRGLG DQSASRTSPG RVDLPGSSTT LTKSFTSSSP 310 320 330 340 350 360 SSPSRAKGGD DSKICPSLCS YSGLNGNPSS ELDYCSTYRQ HLDVPRDSPR AISFKNGWQM 370 380 390 400 410 420 ARQNAEIWSS TEETVSPKIK SRSCDDLLND DCDSFPDPKV KSESMGSLLC EEDSKESCPM 430 440 450 460 470 480 AWGSPYVPEV RSNGRSRIRH RSARNAPGFL KMYKKMHRIN RKDLMNSEVI CSVKSRILQY 490 500 510 520 530 540 ESEQQHKDLL RAWSQCSTEE VPRDMVPTRI SEFEKLIQKS KSMPNLGDDM LSPVTLEPPQ 550 560 570 580 590 600 NGLCPKRRFS IEYLLEEENQ SGPPARGRRG CQSNALVPIH IEVTSDEQPR AHVEFSDSDQ 610 620 630 640 650 660 DGVVSDHSDY IHLEGSSFCS ESDFDHFSFT SSESFYGSSH HHHHHHHHHH RHLISSCKGR 670 680 690 700 710 720 CPASYTRFTT MLKHERARHE NTEEPRRQEM DPGLSKLAFL VSPVPFRRKK NSAPKKQTEK 730 740 750 760 770 780 AKCKASVFEA LDSALKDICD QIKAEKKRGS LPDNSILHRL ISELLPDVPE RNSSLRALRR 790 800 810 820 830 840 SPLHQPLHPL PPDGAIHCPP YQNDCGRMPR SASFQDVDTA NSSCHHQDRG GALQDRESPR 850 860 870 880 890 900 SYSSTLTDMG RSAPRERRGT PEKEKLPAKA VYDFKAQTSK ELSFKKGDTV YILRKIDQNW 910 920 930 940 950 960 YEGEHHGRVG IFPISYVEKL TPPEKAQPAR PPPPAQPGEI GEAIAKYNFN ADTNVELSLR 970 980 990 1000 1010 1020 KGDRVILLKR VDQNWYEGKI PGTNRQGIFP VSYVEVVKKN TKGAEDYPDP PIPHSYSSDR 1030 1040 1050 1060 1070 1080 IHSLSSNKPQ RPVFTHENIQ GGGEPFQALY NYTPRNEDEL ELRESDVIDV MEKCDDGWFV 1090 1100 GTSRRTKFFG TFPGNYVKRL
	Isoform 2 (ArgBP2a) [UniParc]. Checksum: 92504C18534CD94B	FASTA	666	74,778
	10 20 30 40 50 60 MNTGRDSQSP DSAKGFRSVR PNLQDKRSPT QSQITVNGNS GGAVSPMSYY QRPFSPSAYS 70 80 90 100 110 120 LPASLNSSIV MQHGTSLDST DTYPQHAQSL DGTTSSSIPL YRSSEEEKRV TVIKAPHYPG 130 140 150 160 170 180 IGPVDESGIP TAIRTTVDRP KDWYKTMFKQ IHMVHKPDDD TDMYNTPYTY NAGLYNPPYS 190 200 210 220 230 240 AQSHPAAKTQ TYRPLSKSHS DNSPNAFKDA SSPVPPPHVP PPVPPLRPRD RSSTEKHDWD 250 260 270 280 290 300 PPDRKVDTRK FRSEPRSIFE YEPGKSSILQ HERPTDRINP DDIDLENEPW YKFFSELEFG 310 320 330 340 350 360 RPPPKKPLDY VQDHSSGVFN EASLYQSSID RSLERPMSSA SMASDFRKRR KSEPAVGPPR 370 380 390 400 410 420 GLGDQSASRT SPGRVDLPGS STTLTKSFTS SSPSSPSRAK DRESPRSYSS TLTDMGRSAP 430 440 450 460 470 480 RERRGTPEKE KLPAKAVYDF KAQTSKELSF KKGDTVYILR KIDQNWYEGE HHGRVGIFPI 490 500 510 520 530 540 SYVEKLTPPE KAQPARPPPP AQPGEIGEAI AKYNFNADTN VELSLRKGDR VILLKRVDQN 550 560 570 580 590 600 WYEGKIPGTN RQGIFPVSYV EVVKKNTKGA EDYPDPPIPH SYSSDRIHSL SSNKPQRPVF 610 620 630 640 650 660 THENIQGGGE PFQALYNYTP RNEDELELRE SDVIDVMEKC DDGWFVGTSR RTKFFGTFPG NYVKRL
	Isoform 3 [UniParc]. Checksum: 8CDEF6E34D5F972F	FASTA	645	71,899
	10 20 30 40 50 60 MSYYQRPFSP SAYSLPASLN SSIVMQHGTS LDSTDTYPQH AQSLDGTTSS SIPLYRSSEE 70 80 90 100 110 120 EKRVTVIKAP HYPGIGPVDE SGIPTAIRTT VDRPKDWYKT MFKQIHMVHK PDDDTDMYNT 130 140 150 160 170 180 PYTYNAGLYN PPYSAQSHPA AKTQTYRPLS KSHSDNSPNA FKDASSPVPP PHVPPPVPPL 190 200 210 220 230 240 RPRDRSSTEK HDWDPPDRKV DTRKFRSEPR SIFEYEPGKS SILQHERPPP LPTTPTPVPR 250 260 270 280 290 300 EPGRKPLSSS RLGEVTGSPS PPPRSGAPTP SSRAPALSPT RPPKKPLDYV QDHSSGVFNE 310 320 330 340 350 360 ASLYQSSIDR SLERPMSSAS MASDFRKRRK SEPAVGPPRG LGDQSASRTS PGRVDLPGSS 370 380 390 400 410 420 TTLTKSFTSS SPSSPSRAKD RESPRSYSST LTDMGRSAPR ERRGTPEKEK LPAKAVYDFK 430 440 450 460 470 480 AQTSKELSFK KGDTVYILRK IDQNWYEGEH HGRVGIFPIS YVEKLTPPEK AQPARPPPPA 490 500 510 520 530 540 QPGEIGEAIA KYNFNADTNV ELSLRKGDRV ILLKRVDQNW YEGKIPGTNR QGIFPVSYVE 550 560 570 580 590 600 VVKKNTKGAE DYPDPPIPHS YSSDRIHSLS SNKPQRPVFT HENIQGGGEP FQALYNYTPR 610 620 630 640 NEDELELRES DVIDVMEKCD DGWFVGTSRR TKFFGTFPGN YVKRL
	Isoform 4 [UniParc]. Checksum: 1CF7D8E8E49233B8	FASTA	691	76,712
	10 20 30 40 50 60 MNTGRDSQSP DSAKGFRSVR PNLQDKRSPT QSQITVNGNS GGAVSPMSYY QRPFSPSAYS 70 80 90 100 110 120 LPASLNSSIV MQHGTSLDST DTYPQHAQSL DGTTSSSIPL YRSSEEEKRV TVIKAPHYPG 130 140 150 160 170 180 IGPVDESGIP TAIRTTVDRP KDWYKTMFKQ IHMVHKPDDD TDMYNTPYTY NAGLYNPPYS 190 200 210 220 230 240 AQSHPAAKTQ TYRPLSKSHS DNSPNAFKDA SSPVPPPHVP PPVPPLRPRD RSSTEKHDWD 250 260 270 280 290 300 PPDRKVDTRK FRSEPRSIFE YEPGKSSILQ HERPPPLPTT PTPVPREPGR KPLSSSRLGE 310 320 330 340 350 360 VTGSPSPPPR SGAPTPSSRA PALSPTRPPK KPLDYVQDHS SGVFNEASLY QSSIDRSLER 370 380 390 400 410 420 PMSSASMASD FRKRRKSEPA VGPPRGLGDQ SASRTSPGRV DLPGSSTTLT KSFTSSSPSS 430 440 450 460 470 480 PSRAKDRESP RSYSSTLTDM GRSAPRERRG TPEKEKLPAK AVYDFKAQTS KELSFKKGDT 490 500 510 520 530 540 VYILRKIDQN WYEGEHHGRV GIFPISYVEK LTPPEKAQPA RPPPPAQPGE IGEAIAKYNF 550 560 570 580 590 600 NADTNVELSL RKGDRVILLK RVDQNWYEGK IPGTNRQGIF PVSYVEVVKK NTKGAEDYPD 610 620 630 640 650 660 PPIPHSYSSD RIHSLSSNKP QRPVFTHENI QGGGEPFQAL YNYTPRNEDE LELRESDVID 670 680 690 VMEKCDDGWF VGTSRRTKFF GTFPGNYVKR L
	Isoform 5 (ArgBP2b) [UniParc]. Checksum: 455C7808CED30D41	FASTA	645	71,170
	10 20 30 40 50 60 MNTGRDSQSP DSAKGFRSVR PNLQDKRSPT QSQITVNGNS GGAVSPMSYY QRPFSPSAYS 70 80 90 100 110 120 LPASLNSSIV MQHGTSLDST DTYPQHAQSL DGTTSSSIPL YRSSEEEKRV TVIKAPHYPG 130 140 150 160 170 180 IGPVDESGIP TAIRTTVDRP KDWYKTMFKQ IHMVHKPDDD TDMYNTPYTY NAGLYNPPYS 190 200 210 220 230 240 AQSHPAAKTQ TYRPLSKSHS DNSPNAFKDA SSPVPPPHVP PPVPPLRPRD RSSTEKHDWD 250 260 270 280 290 300 PPDRKVDTRK FRSEPRSIFE YEPGKSSILQ HERPPPLPTT PTPVPREPGR KPLSSSRLGE 310 320 330 340 350 360 VTGSPSPPPR SGAPTPSSRA PALSPTRPPK KPLDYVQDHS SGVFNEASLY QSSIDRSLER 370 380 390 400 410 420 PMSSASMASD FRKRRKSEPA VGPPRGLGDQ SASRTSPGRV DLPGSSTTLT KSFTSSSPSS 430 440 450 460 470 480 PSRAKDRESP RSYSSTLTDM GRSAPRERRG TPEKEKLPAK AVYDFKAQTS KELSFKKGDT 490 500 510 520 530 540 VYILRKIDQN WYEGEHHGRV GIFPISYVEK LTPPEKAQPA RPPPPAQPGE IGEAIAKYNF 550 560 570 580 590 600 NADTNVELSL RKGDRVILLK RVDQNWYEGK IPGTNRQGIF PVSYVEVVKK NTKGAEDYPD 610 620 630 640 PPIPHSYSSD RIHSLSSNKP QRPVFTHENI QGGGEPFQAL GYTLT
	Isoform 6 (Sorbin) [UniParc]. Checksum: 95AE8B49881FCC12	FASTA	156	17,976
	10 20 30 40 50 60 MKATTPLQTV DRPKDWYKTM FKQIHMVHKP DDDTDMYNTP YTYNAGLYNP PYSAQSHPAA 70 80 90 100 110 120 KTQTYRPLSK SHSDNSPNAF KDASSPVPPP HVPPPVPPLR PRDRSSTEKH DWDPPDRKVD 130 140 150 TRKFRSEPRS IFEYEPGKSS ILQHERPVSK PQAGRR
	Isoform 7 [UniParc]. Checksum: 1D2245E4FC6037EB	FASTA	1,004	113,555
	10 20 30 40 50 60 MKATTPLQTV DRPKDWYKTM FKQIHMVHKP GLYNPPYSAQ SHPAAKTQTY RPLSKSHSDN 70 80 90 100 110 120 SPNAFKDASS PVPPPHVPPP VPPLRPRDRS STEKHDWDPP DRKVDTRKFR SEPRSIFEYE 130 140 150 160 170 180 PGKSSILQHE RPASLYQSSI DRSLERPMSS ASMASDFRKR RKSEPAVGPP RGLGDQSASR 190 200 210 220 230 240 TSPGRVDLPG SSTTLTKSFT SSSPSSPSRA KGGDDSKICP SLCSYSGLNG NPSSELDYCS 250 260 270 280 290 300 TYRQHLDVPR DSPRAISFKN GWQMARQNAE IWSSTEETVS PKIKSRSCDD LLNDDCDSFP 310 320 330 340 350 360 DPKVKSESMG SLLCEEDSKE SCPMAWGSPY VPEVRSNGRS RIRHRSARNA PGFLKMYKKM 370 380 390 400 410 420 HRINRKDLMN SEVICSVKSR ILQYESEQQH KDLLRAWSQC STEEVPRDMV PTRISEFEKL 430 440 450 460 470 480 IQKSKSMPNL GDDMLSPVTL EPPQNGLCPK RRFSIEYLLE EENQSGPPAR GRRGCQSNAL 490 500 510 520 530 540 VPIHIEVTSD EQPRAHVEFS DSDQDGVVSD HSDYIHLEGS SFCSESDFDH FSFTSSESFY 550 560 570 580 590 600 GSSHHHHHHH HHHHRHLISS CKGRCPASYT RFTTMLKHER ARHENTEEPR RQEMDPGLSK 610 620 630 640 650 660 LAFLVSPVPF RRKKNSAPKK QTEKAKCKAS VFEALDSALK DICDQIKAEK KRGSLPDNSI 670 680 690 700 710 720 LHRLISELLP DVPERNSSLR ALRRSPLHQP LHPLPPDGAI HCPPYQNDCG RMPRSASFQD 730 740 750 760 770 780 VDTANSSCHH QDRGGALQDR ESPRSYSSTL TDMGRSAPRE RRGTPEKEKL PAKAVYDFKA 790 800 810 820 830 840 QTSKELSFKK GDTVYILRKI DQNWYEGEHH GRVGIFPISY VEKLTPPEKA QPARPPPPAQ 850 860 870 880 890 900 PGEIGEAIAK YNFNADTNVE LSLRKGDRVI LLKRVDQNWY EGKIPGTNRQ GIFPVSYVEV 910 920 930 940 950 960 VKKNTKGAED YPDPPIPHSY SSDRIHSLSS NKPQRPVFTH ENIQGGGEPF QALYNYTPRN 970 980 990 1000 EDELELRESD VIDVMEKCDD GWFVGTSRRT KFFGTFPGNY VKRL
	Isoform 8 [UniParc]. Checksum: D72A9CE26ADB7BAD	FASTA	661	73,868
	10 20 30 40 50 60 MNTGRDSQSP DSAWRSYNDG NQETLNGDAT YSSLAAKGFR SVRPNLQDKR SPTQSQITVN 70 80 90 100 110 120 GNSGGAVSPM SYYQRPFSPS AYSLPASLNS SIVMQHGTSL DSTDTYPQHA QSLDGTTSSS 130 140 150 160 170 180 IPLYRSSEEE KRVTVIKAPH YPGIGPVDES GIPTAIRTTV DRPKDWYKTM FKQIHMVHKP 190 200 210 220 230 240 DDDTDMYNTP YTYNAGLYNP PYSAQSHPAA KTQTYRPLSK SHSDNSPNAF KDASSPVPPP 250 260 270 280 290 300 HVPPPVPPLR PRDRSSTEKH DWDPPDRKVD TRKFRSEPRS IFEYEPGKSS ILQHERPPPK 310 320 330 340 350 360 KPLDYVQDHS SGVFNEASLY QSSIDRSLER PMSSASMASD FRKRRKSEPA VGPPRGLGDQ 370 380 390 400 410 420 SASRTSPGRV DLPGSSTTLT KSFTSSSPSS PSRAKDRESP RSYSSTLTDM GRSAPRERRG 430 440 450 460 470 480 TPEKEKLPAK AVYDFKAQTS KELSFKKGDT VYILRKIDQN WYEGEHHGRV GIFPISYVEK 490 500 510 520 530 540 LTPPEKAQPA RPPPPAQPGE IGEAIAKYNF NADTNVELSL RKGDRVILLK RVDQNWYEGK 550 560 570 580 590 600 IPGTNRQGIF PVSYVEVVKK NTKGAEDYPD PPIPHSYSSD RIHSLSSNKP QRPVFTHENI 610 620 630 640 650 660 QGGGEPFQAL YNYTPRNEDE LELRESDVID VMEKCDDGWF VGTSRRTKFF GTFPGNYVKR L
	Isoform 9 [UniParc]. Checksum: 19886F6C073CEB1E	FASTA	644	71,686
	10 20 30 40 50 60 MSVTLTSVKR VQSSPNLLAA GRDSQSPDSA WRSYNDGNQE TLNGDATYSS LAAKGFRSVR 70 80 90 100 110 120 PNLQDKRSPT QSQITVNGNS GGAVSPMSYY QRPFSPSAYS LPASLNSSIV MQHGTSLDST 130 140 150 160 170 180 DTYPQHAQSL DGTTSSSIPL YRSSEEEKRV TVIKAPHYPG IGPVDESGIP TAIRTTVDRP 190 200 210 220 230 240 KDWYKTMFKQ IHMVHKPGLY NPPYSAQSHP AAKTQTYRPL SKSHSDNSPN AFKDASSPVP 250 260 270 280 290 300 PPHVPPPVPP LRPRDRSSTE KHDWDPPDRK VDTRKFRSEP RSIFEYEPGK SSILQHERPA 310 320 330 340 350 360 SLYQSSIDRS LERPMSSASM ASDFRKRRKS EPAVGPPRGL GDQSASRTSP GRVDLPGSST 370 380 390 400 410 420 TLTKSFTSSS PSSPSRAKDR ESPRSYSSTL TDMGRSAPRE RRGTPEKEKL PAKAVYDFKA 430 440 450 460 470 480 QTSKELSFKK GDTVYILRKI DQNWYEGEHH GRVGIFPISY VEKLTPPEKA QPARPPPPAQ 490 500 510 520 530 540 PGEIGEAIAK YNFNADTNVE LSLRKGDRVI LLKRVDQNWY EGKIPGTNRQ GIFPVSYVEV 550 560 570 580 590 600 VKKNTKGAED YPDPPIPHSY SSDRIHSLSS NKPQRPVFTH ENIQGGGEPF QALYNYTPRN 610 620 630 640 EDELELRESD VIDVMEKCDD GWFVGTSRRT KFFGTFPGNY VKRL
	Isoform 10 [UniParc]. Checksum: EB10B42B47D6751B	FASTA	824	91,277
	10 20 30 40 50 60 MYSNEDSRQT IVYSEESNTT MSYTQKITNP LPAASSTDPA PFANINTPVL QEDYRQDSQT 70 80 90 100 110 120 RRISTLKLTH NQDLGSSSPI STPQFSKSVE VPSFLKRPRS LTPNPVPETH TASLSIQIAP 130 140 150 160 170 180 LSGQDLESHK QLPELSPETA KIPLQQERQK SAVAAASQSS DCRVSQITVN GNSGGAVSPM 190 200 210 220 230 240 SYYQRPFSPS AYSLPASLNS SIVMQHGTSL DSTDTYPQHA QSLDGTTSSS IPLYRSSEEE 250 260 270 280 290 300 KRVTVIKAPH YPGIGPVDES GIPTAIRTTV DRPKDWYKTM FKQIHMVHKP DDDTDMYNTP 310 320 330 340 350 360 YTYNAGLYNP PYSAQSHPAA KTQTYRPLSK SHSDNSPNAF KDASSPVPPP HVPPPVPPLR 370 380 390 400 410 420 PRDRSSTEKH DWDPPDRKVD TRKFRSEPRS IFEYEPGKSS ILQHERPPPL PTTPTPVPRE 430 440 450 460 470 480 PGRKPLSSSR LGEVTGSPSP PPRSGAPTPS SRAPALSPTR PPKKPLDYVQ DHSSGVFNEA 490 500 510 520 530 540 SLYQSSIDRS LERPMSSASM ASDFRKRRKS EPAVGPPRGL GDQSASRTSP GRVDLPGSST 550 560 570 580 590 600 TLTKSFTSSS PSSPSRAKDR ESPRSYSSTL TDMGRSAPRE RRGTPEKEKL PAKAVYDFKA 610 620 630 640 650 660 QTSKELSFKK GDTVYILRKI DQNWYEGEHH GRVGIFPISY VEKLTPPEKA QPARPPPPAQ 670 680 690 700 710 720 PGEIGEAIAK YNFNADTNVE LSLRKGDRVI LLKRVDQNWY EGKIPGTNRQ GIFPVSYVEV 730 740 750 760 770 780 VKKNTKGAED YPDPPIPHSY SSDRIHSLSS NKPQRPVFTH ENIQGGGEPF QALYNYTPRN 790 800 810 820 EDELELRESD VIDVMEKCDD GWFVGTSRRT KFFGTFPGNY VKRL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"ArgBP2, a multiple Src homology 3 domain-containing, Arg/Abl-interacting protein, is phosphorylated in v-Abl-transformed cells and localized in stress fibers and cardiocyte Z-disks." Wang B., Golemis E.A., Kruh G.D. J. Biol. Chem. 272:17542-17550(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2 AND 5), NUCLEOTIDE SEQUENCE [MRNA] OF 1-1049 (ISOFORM 4), PHOSPHORYLATION, TISSUE SPECIFICITY, SUBCELLULAR LOCATION, INTERACTION WITH ABL1 AND ABL2, FUNCTION. Tissue: Brain.
[2]	"Coding region of the sorbin gene in different species." Wahbi K., Magaud J.-P., Pansu D., Descroix-Vagne M. Peptides 22:2045-2053(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 6), AMIDATION AT ALA-153 (ISOFORM 6), TISSUE SPECIFICITY.
[3]	"Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." Nagase T., Ishikawa K., Suyama M., Kikuno R., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O. DNA Res. 5:277-286(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Brain.
[4]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 7 AND 8). Tissue: Thalamus and Urinary bladder.
[5]	Suzuki Y., Sugano S., Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S. Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 9 AND 10). Tissue: Heart and Hepatoma.
[6]	"Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H. , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K. Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[7]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[8]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3). Tissue: Lymph.
[9]	"Cbl-ArgBP2 complex mediates ubiquitination and degradation of c-Abl." Soubeyran P., Barac A., Szymkiewicz I., Dikic I. Biochem. J. 370:29-34(2003) [PubMed] [Europe PMC] [Abstract] Cited for: INTERACTION WITH CBL, UBIQUITINATION BY CBL, FUNCTION.
[10]	"Involvement of palladin and alpha-actinin in targeting of the Abl/Arg kinase adaptor ArgBP2 to the actin cytoskeleton." Roenty M., Taivainen A., Moza M., Kruh G.D., Ehler E., Carpen O. Exp. Cell Res. 310:88-98(2005) [PubMed] [Europe PMC] [Abstract] Cited for: INTERACTION WITH PALLD AND ACTN, SUBCELLULAR LOCATION.
[11]	"ArgBP2gamma interacts with Akt and p21-activated kinase-1 and promotes cell survival." Yuan Z.-Q., Kim D., Kaneko S., Sussman M., Bokoch G.M., Kruh G.D., Nicosia S.V., Testa J.R., Cheng J.Q. J. Biol. Chem. 280:21483-21490(2005) [PubMed] [Europe PMC] [Abstract] Cited for: INTERACTION WITH AKT1 AND PAK1, UBIQUITINATION BY CBL, PHOSPHORYLATION.
[12]	"A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-157; THR-277; SER-301 AND SER-302, PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-258 AND SER-260 (ISOFORM 3), PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-304 AND SER-306 (ISOFORMS 4 AND 5), MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[13]	"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis." Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M. Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-157; SER-298; SER-299 AND SER-302, PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-258 AND SER-260 (ISOFORM 3), PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-304 AND SER-306 (ISOFORMS 4 AND 5), MASS SPECTROMETRY. Tissue: Cervix carcinoma.
+	Additional computationally mapped references.

Web resources

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF049884 mRNA. Translation: AAC05508.1. AF049885 mRNA. Translation: AAC05509.1. AB018320 mRNA. Translation: BAA34497.2. Different initiation. AK293400 mRNA. Translation: BAH11501.1. AK296461 mRNA. Translation: BAH12362.1. AK225327 mRNA. No translation available. AK225812 mRNA. No translation available. AC093797 Genomic DNA. No translation available. AC096659 Genomic DNA. No translation available. AC104805 Genomic DNA. No translation available. AC108472 Genomic DNA. No translation available. CH471056 Genomic DNA. Translation: EAX04630.1. CH471056 Genomic DNA. Translation: EAX04631.1. CH471056 Genomic DNA. Translation: EAX04632.1. CH471056 Genomic DNA. Translation: EAX04635.1. CH471056 Genomic DNA. Translation: EAX04636.1. BC011883 mRNA. Translation: AAH11883.1.
IPI	IPI00061793. IPI00477577. IPI00747799. IPI00787549. IPI00900281. IPI00900295. IPI00921885. IPI00923523. IPI00923573. IPI01013920.
RefSeq	NP_001139142.1. NM_001145670.1. NP_001139143.1. NM_001145671.2. NP_001139144.1. NM_001145672.1. NP_001139145.1. NM_001145673.1. NP_001139146.1. NM_001145674.1. NP_001257700.1. NM_001270771.1. NP_003594.3. NM_003603.6. NP_066547.1. NM_021069.4.
UniGene	Hs.619806. Hs.655143.
3D structure databases
HSSP	HSSP built from PDB template 2CT3 based on UniProtKB O60504.
ProteinModelPortal	O94875.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-31634N.
IntAct	O94875. 9 interactions.
MINT	MINT-196404.
STRING	9606.ENSP00000284776.
PTM databases
PhosphoSite	O94875.
Proteomic databases
PaxDb	O94875.
PRIDE	O94875.
Protocols and materials databases
DNASU	8470.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000284776; ENSP00000284776; ENSG00000154556. ENST00000393528; ENSP00000377162; ENSG00000154556. ENST00000418609; ENSP00000397482; ENSG00000154556. ENST00000431808; ENSP00000411764; ENSG00000154556. ENST00000437304; ENSP00000396008; ENSG00000154556. ENST00000448662; ENSP00000409158; ENSG00000154556. ENST00000449407; ENSP00000397262; ENSG00000154556.
GeneID	8470.
KEGG	hsa:8470.
UCSC	uc003iya.3. human. uc003iyb.3. human. uc003iyi.3. human. uc003iyl.3. human.
Organism-specific databases
CTD	8470.
GeneCards	GC04M186506.
HGNC	HGNC:24098. SORBS2.
HPA	HPA036754.
neXtProt	NX_O94875.
PharmGKB	PA142670890.
HUGE	Search...
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG256936.
HOGENOM	HOG000294090.
HOVERGEN	HBG108509.
InParanoid	O94875.
OrthoDB	EOG4J117C.
Gene expression databases
ArrayExpress	O94875.
Bgee	O94875.
CleanEx	HS_SORBS2.
Genevestigator	O94875.
Family and domain databases
InterPro	IPR000108. p67phox. IPR011511. SH3_2. IPR001452. SH3_domain. IPR003127. Sorb. IPR007087. Znf_C2H2. [Graphical view]
Pfam	PF00018. SH3_1. 2 hits. PF07653. SH3_2. 1 hit. PF02208. Sorb. 1 hit. [Graphical view]
PRINTS	PR00499. P67PHOX. PR00452. SH3DOMAIN.
SMART	SM00326. SH3. 3 hits. SM00459. Sorb. 1 hit. [Graphical view]
SUPFAM	SSF50044. SH3. 3 hits.
PROSITE	PS50002. SH3. 3 hits. PS50831. SOHO. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	SORBS2. human.
GenomeRNAi	8470.
NextBio	31696.

Entry information

Entry name

SRBS2_HUMAN

Accession

Primary (citable) accession number: O94875
Secondary accession number(s): A6NEK9 , B7Z1G5, B7Z3X6, C9JKV9, D3DP62, D3DP63, E9PAS5, E9PAW4, G3XAI0, O60592, O60593, Q96EX0

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 22, 2008
Last sequence update:	July 22, 2008
Last modified:	May 1, 2013
This is version 105 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.