Reviewed, UniProtKB/Swiss-Prot O94522 (RSC7_SCHPO)

Names and origin

Protein names

Recommended name:
Chromatin structure-remodeling complex subunit rsc7

Alternative name(s):
Remodel the structure of chromatin complex subunit 7

Gene names

Name:	rsc7
ORF Names:	SPCC1281.05

Organism

Schizosaccharomyces pombe (Fission yeast) [Complete proteome]

Taxonomic identifier

4896 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

Protein attributes

Sequence length	390 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particularly membrane and organelle development genes. Ref.4
Subunit structure	Component of the RSC complex composed of at least arp9, arp42, rsc1, rsc4, rsc7, rsc9, rsc58, sfh1, snf21, ssr1, ssr2, ssr3 and ssr4. The complex probably interacts with histone and histone variant components of centromeric chromatin.
Subcellular location	Nucleus Ref.2.
Sequence similarities	Belongs to the RSC7/SWP82 family. RSC7 subfamily.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Molecular function	Chromatin regulator
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	chromatin modification Inferred from electronic annotation. Source: UniProtKB-KW gene-specific transcription from RNA polymerase II promoter Inferred by curator. Source: GeneDB_SPombe regulation of cellular transcription Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	RSC complex Ref.4 Inferred from direct assay. Source: GeneDB_SPombe nuclear chromatin Inferred by curator. Source: GeneDB_SPombe
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 390	390	Chromatin structure-remodeling complex subunit rsc7		PRO_0000373988
Regions
	Compositional bias	38 – 41	4	Poly-Asp
Amino acid modifications
	Modified residue	36	1	Phosphoserine Ref.3
	Modified residue	37	1	Phosphoserine Ref.3

Sequences

	Sequence		Length	Mass (Da)
	O94522-1 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 04123B06A14C7790	FASTA	390	44,009
	10 20 30 40 50 60 MDSTAGSDAS TPTNHTVSSK KRRGRPPKGS YAAYGSSDDD DEEYSGRTRR RNRNTRPRVS 70 80 90 100 110 120 APSSSSTVVP KDLYSHRATL EDDELNFGVV DPEGEKKVNE LGYLNGGREY RCRTFTCLGR 130 140 150 160 170 180 GNRLYMLSTE PARAMGYRDS YLLFLKHRSL HKIIVDDSEK WDLIERNIIP HSYKGRAVGI 190 200 210 220 230 240 VAARSIFREF GARIIVGGRR IVDDYWEGEF RARGFVEGEL ADPDDKLPPP GMPYNRNQYV 250 260 270 280 290 300 AWHGASAVYH PQPSLEAQLP AAARKRKKEP PKDATWLFQH AKATAAYNND ITKYLVQKQD 310 320 330 340 350 360 IGYFEPHTNL LHVPLNTQPT KTHWIQAKTG TECPAPKLDI LVALNSDVAP QVSIANIPPS 370 380 390 VYASCPLHVQ EAIRKRQEQE IRSIRLNSMY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P. Nature 415:871-880(2002) [PubMed: 11859360] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 38366 / 972.
[2]	"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe." Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M. Nat. Biotechnol. 24:841-847(2006) [PubMed: 16823372] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[3]	"Phosphoproteome analysis of fission yeast." Wilson-Grady J.T., Villen J., Gygi S.P. J. Proteome Res. 7:1088-1097(2008) [PubMed: 18257517] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-36 AND SER-37, MASS SPECTROMETRY.
[4]	"Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast." Monahan B.J., Villen J., Marguerat S., Baehler J., Gygi S.P., Winston F. Nat. Struct. Mol. Biol. 15:873-880(2008) [PubMed: 18622392] [Abstract] Cited for: IDENTIFICATION IN THE RSC COMPLEX, FUNCTION OF THE COMPLEX, MASS SPECTROMETRY.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU329672 Genomic DNA. Translation: CAA22826.1.
PIR	T40924.
RefSeq	NP_588169.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	O94522.
Genome annotation databases
GeneID	2538836.
GenomeReviews	Gene locus rsc7 in contig CU329672_GR.
KEGG	spo:SPCC1281.05.
NMPDR	fig|4896.1.peg.507.
Organism-specific databases
GeneDB_Spombe	SPCC1281.05.
Phylogenomic databases
eggNOG	fuNOG06088.
OrthoDB	EOG9JM95R.
PhylomeDB	O94522.
Gene expression databases
ArrayExpress	O94522.
Family and domain databases
InterPro	IPR013933. CRC_Rsc7/Swp82. [Graphical view]
Pfam	PF08624. CRC_subunit. 1 hit. [Graphical view]
ProDom	PD041931. CRC_Rsc7/Swp82. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

RSC7_SCHPO

Accession

Primary (citable) accession number: O94522

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 5, 2009
Last sequence update:	May 1, 1999
Last modified:	January 19, 2010
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)