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Protein

Glucan endo-1,3-alpha-glucosidase agn2

Gene

agn2

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in the endolysis of the ascus wall.1 Publication

Catalytic activityi

Endohydrolysis of (1->3)-alpha-D-glucosidic linkages in isolichenin, pseudonigeran and nigeran.

GO - Molecular functioni

  • glucan endo-1,3-alpha-glucosidase activity Source: PomBase

GO - Biological processi

  • alpha-glucan catabolic process involved in ascospore release from ascus Source: PomBase
  • ascospore release from ascus Source: PomBase
  • cell division Source: UniProtKB-KW
  • fungal-type cell wall disassembly involved in conjugation with cellular fusion Source: PomBase
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Cell cycle, Cell division

Protein family/group databases

CAZyiGH71. Glycoside Hydrolase Family 71.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucan endo-1,3-alpha-glucosidase agn2 (EC:3.2.1.59)
Alternative name(s):
Endo-1,3-alpha-glucanase agn2
Gene namesi
Name:agn2
ORF Names:SPBC646.06c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC646.06c.
PomBaseiSPBC646.06c. agn2.

Subcellular locationi

GO - Cellular componenti

  • actin fusion focus Source: PomBase
  • cytosol Source: PomBase
  • nucleus Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 433433Glucan endo-1,3-alpha-glucosidase agn2PRO_0000119035Add
BLAST

Proteomic databases

MaxQBiO94510.

Interactioni

Protein-protein interaction databases

BioGridi277637. 7 interactions.
MINTiMINT-4684782.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 71 family.Curated

Phylogenomic databases

HOGENOMiHOG000158769.
InParanoidiO94510.
KOiK08254.
OMAiKTISTSC.
OrthoDBiEOG092C2JYU.
PhylomeDBiO94510.

Family and domain databases

CDDicd11577. GH71. 1 hit.
InterProiIPR005197. Glyco_hydro_71.
[Graphical view]
PfamiPF03659. Glyco_hydro_71. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O94510-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASLTTALPN KAVVAHFMMG LTYNYAQSDF QNDIQNAISL GLDGFVLNFG
60 70 80 90 100
NDSWMMSKLT LMYNAADALN LQFLLYLNLD MSEMSTVPAS TLVTYVQTFA
110 120 130 140 150
NRGHQARINN NVVVGTFLGQ DINFGQSSVN QGWQVAFKNA LASAGINIFF
160 170 180 190 200
MPTWPLDAST IYQTYPVADG FCKWNCWPYY TSSPTSDAED LVYIQNSKAT
210 220 230 240 250
NKKYMATVSP IFYTHFTSKN YSFFSEGLWF TRWMQLIKDQ PNYVQVLTWN
260 270 280 290 300
DYGESTYIGP TNYAADFPVI GSNSHEWVDS FTHAPLSYSL PLFIQMYKQN
310 320 330 340 350
TTGLPSNFSG ISQLYVTYRV HSKNATASSD SIPRPDNYQN SSDVISVISF
360 370 380 390 400
AKSSYTLRVS VNGTVLGTTN VNAGVQSANV SFIVNNTAAA GLPLFQILNG
410 420 430
TTVIAQGYGP LNILGNNSVV LYNFNFCTTR ISW
Length:433
Mass (Da):48,066
Last modified:August 16, 2004 - v2
Checksum:i7FA86E53523BC675
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY626902 mRNA. Translation: AAT84065.1.
CU329671 Genomic DNA. Translation: CAH58744.1.
PIRiT40582.
RefSeqiXP_001713124.1. XM_001713072.2.

Genome annotation databases

EnsemblFungiiSPBC646.06c.1; SPBC646.06c.1:pep; SPBC646.06c.
GeneIDi2541122.
KEGGispo:SPBC646.06c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY626902 mRNA. Translation: AAT84065.1.
CU329671 Genomic DNA. Translation: CAH58744.1.
PIRiT40582.
RefSeqiXP_001713124.1. XM_001713072.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi277637. 7 interactions.
MINTiMINT-4684782.

Protein family/group databases

CAZyiGH71. Glycoside Hydrolase Family 71.

Proteomic databases

MaxQBiO94510.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC646.06c.1; SPBC646.06c.1:pep; SPBC646.06c.
GeneIDi2541122.
KEGGispo:SPBC646.06c.

Organism-specific databases

EuPathDBiFungiDB:SPBC646.06c.
PomBaseiSPBC646.06c. agn2.

Phylogenomic databases

HOGENOMiHOG000158769.
InParanoidiO94510.
KOiK08254.
OMAiKTISTSC.
OrthoDBiEOG092C2JYU.
PhylomeDBiO94510.

Miscellaneous databases

PROiO94510.

Family and domain databases

CDDicd11577. GH71. 1 hit.
InterProiIPR005197. Glyco_hydro_71.
[Graphical view]
PfamiPF03659. Glyco_hydro_71. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiAGN2_SCHPO
AccessioniPrimary (citable) accession number: O94510
Secondary accession number(s): Q5ZEQ1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: August 16, 2004
Last modified: September 7, 2016
This is version 91 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.