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Reviewed, UniProtKB/Swiss-Prot O94510 (AGN2_SCHPO)

Last modified June 15, 2010. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
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Names and originHide

Protein namesRecommended name:
Glucan endo-1,3-alpha-glucosidase agn2
EC=3.2.1.59
Alternative name(s):
Endo-1,3-alpha-glucanase agn2
Gene names
Name:agn2
ORF Names:SPBC646.06c
OrganismSchizosaccharomyces pombe (Fission yeast) [Complete proteome]
Taxonomic identifier4896 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces
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Protein attributesHide

Sequence length433 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.
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General annotation (Comments)Hide

Function

Involved in the endolysis of the ascus wall. Ref.1

Catalytic activity

Endohydrolysis of (1->3)-alpha-D-glucosidic linkages in isolichenin, pseudonigeran and nigeran.

Subcellular location

Cytoplasm Ref.1.

Sequence similarities

Belongs to the glycosyl hydrolase 71 family.

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OntologiesHide

Keywords
   Biological processCell cycle
Cell division
   Cellular componentCytoplasm
   Molecular functionGlycosidase
Hydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcell cycle

Inferred from electronic annotation. Source: UniProtKB-KW

cell division

Inferred from electronic annotation. Source: UniProtKB-KW

metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

spore germination

Inferred from mutant phenotype. Source: GeneDB_SPombe

   Cellular componentascospore wall

Inferred from direct assay. Source: GeneDB_SPombe

cell surface

Inferred from direct assay. Source: GeneDB_SPombe

cytosol

Inferred from direct assay. Source: GeneDB_SPombe

nucleus

Inferred from direct assay. Source: GeneDB_SPombe

   Molecular functionglucan endo-1,3-alpha-glucosidase activity

Traceable author statement. Source: GeneDB_SPombe

Complete GO annotation...
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Sequence annotation (Features)Hide

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 433433Glucan endo-1,3-alpha-glucosidase agn2
PRO_0000119035
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SequencesHide

Sequence LengthMass (Da)Tools
O94510-1 [UniParc].

Last modified August 16, 2004. Version 2.
Checksum: 7FA86E53523BC675

FASTA43348,066
        10         20         30         40         50         60 
MASLTTALPN KAVVAHFMMG LTYNYAQSDF QNDIQNAISL GLDGFVLNFG NDSWMMSKLT 

        70         80         90        100        110        120 
LMYNAADALN LQFLLYLNLD MSEMSTVPAS TLVTYVQTFA NRGHQARINN NVVVGTFLGQ 

       130        140        150        160        170        180 
DINFGQSSVN QGWQVAFKNA LASAGINIFF MPTWPLDAST IYQTYPVADG FCKWNCWPYY 

       190        200        210        220        230        240 
TSSPTSDAED LVYIQNSKAT NKKYMATVSP IFYTHFTSKN YSFFSEGLWF TRWMQLIKDQ 

       250        260        270        280        290        300 
PNYVQVLTWN DYGESTYIGP TNYAADFPVI GSNSHEWVDS FTHAPLSYSL PLFIQMYKQN 

       310        320        330        340        350        360 
TTGLPSNFSG ISQLYVTYRV HSKNATASSD SIPRPDNYQN SSDVISVISF AKSSYTLRVS 

       370        380        390        400        410        420 
VNGTVLGTTN VNAGVQSANV SFIVNNTAAA GLPLFQILNG TTVIAQGYGP LNILGNNSVV 

       430 
LYNFNFCTTR ISW

« Hide

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ReferencesHide

« Hide 'large scale' references
[1]"Role of the alpha-glucanase Agn1p in fission-yeast cell separation."
Dekker N., Speijer D., Grun C.H., Van Den Berg M., De Haan A., Hochstenbach F.
Mol. Biol. Cell 15:3903-3914(2004) [PubMed: 15194814] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, SUBCELLULAR LOCATION.
Strain: ND080.
[2]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed: 11859360] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 38366 / 972.
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Cross-referencesHide

Sequence databases

EMBL
GenBank
DDBJ		AY626902 mRNA. Translation: AAT84065.1.
CU329671 Genomic DNA. Translation: CAH58744.1.
PIRT40582.
RefSeqXP_001713124.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGO94510.

Protein family/group databases

CAZyGH71. Glycoside Hydrolase Family 71.

Genome annotation databases

EnsemblFungiSPBC646.06c-1; SPBC646.06c-1; SPBC646.06c.
GeneID2541122.
GenomeReviewsGene locus agn2 in contig CU329671_GR.
KEGGspo:SPBC646.06c.

Organism-specific databases

GeneDB_SpombeSPBC646.06c.

Phylogenomic databases

HOGENOMHBG332366.
OMANKNWIYR.
OrthoDBEOG92BZRR.

Enzyme and pathway databases

BRENDA3.2.1.59. 653.

Gene expression databases

ArrayExpressO94510.

Family and domain databases

InterProIPR005197. Glyco_hydro_71.
[Graphical view]
PfamPF03659. Glyco_hydro_71. 1 hit.
[Graphical view]
ProtoNetSearch...
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Entry informationHide

Entry nameAGN2_SCHPO
AccessionPrimary (citable) accession number: O94510
Secondary accession number(s): Q5ZEQ1
Entry history
Integrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: August 16, 2004
Last modified: June 15, 2010
This is version 54 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)
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Relevant documentsHide

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents