ID   OYEC_SCHPO              Reviewed;         395 AA.
AC   O94467;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   16-JUN-2009, entry version 38.
DE   RecName: Full=Putative NADPH dehydrogenase C23G7.10c;
DE            EC=1.6.99.1;
DE   AltName: Full=Old yellow enzyme homolog 3;
GN   ORFNames=SPBC23G7.10c;
OS   Schizosaccharomyces pombe (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales;
OC   Schizosaccharomycetaceae; Schizosaccharomyces.
OX   NCBI_TaxID=4896;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 38366 / 972;
RX   MEDLINE=21848401; PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M.,
RA   Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A.,
RA   Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G.,
RA   Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K.,
RA   James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J.,
RA   Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C.,
RA   Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E.,
RA   Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S.,
RA   Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K.,
RA   Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S.,
RA   Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B.,
RA   Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S.,
RA   Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D.,
RA   Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R.,
RA   Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B.,
RA   Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S.,
RA   Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M.,
RA   Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G.,
RA   Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J.,
RA   Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L.,
RA   Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J.,
RA   Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- CATALYTIC ACTIVITY: NADPH + acceptor = NADP(+) + reduced acceptor.
CC   -!- COFACTOR: FMN (By similarity).
CC   -!- SUBUNIT: Homodimer or heterodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the NADH:flavin oxidoreductase/NADH oxidase
CC       family.
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DR   EMBL; CU329671; CAA22626.1; -; Genomic_DNA.
DR   PIR; T39956; T39956.
DR   RefSeq; NP_595868.1; -.
DR   GeneID; 2540490; -.
DR   KEGG; spo:SPBC23G7.10c; -.
DR   NMPDR; fig|4896.1.peg.1734; -.
DR   GeneDB_Spombe; SPBC23G7.10c; -.
DR   OMA; O94467; STVAPWL.
DR   BRENDA; 1.6.99.1; 653.
DR   ArrayExpress; O94467; -.
DR   GO; GO:0005829; C:cytosol; IDA:GeneDB_SPombe.
DR   GO; GO:0005634; C:nucleus; IDA:GeneDB_SPombe.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0003959; F:NADPH dehydrogenase activity; IEA:EC.
DR   GO; GO:0033554; P:cellular response to stress; IEP:GeneDB_SPombe.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR001155; OxRdtase_FMN_N.
DR   Gene3D; G3DSA:3.20.20.70; Aldolase_TIM; 1.
DR   Pfam; PF00724; Oxidored_FMN; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome; Flavoprotein; FMN; NADP; Oxidoreductase.
FT   CHAIN         1    395       Putative NADPH dehydrogenase C23G7.10c.
FT                                /FTId=PRO_0000314118.
FT   ACT_SITE    213    213       Proton donor (By similarity).
FT   BINDING     208    208       FMN (By similarity).
FT   BINDING     208    208       Substrate (By similarity).
FT   BINDING     358    358       FMN (By similarity).
FT   BINDING     386    386       Substrate (By similarity).
SQ   SEQUENCE   395 AA;  43684 MW;  EF4687841D9FDA06 CRC64;
     MTIVNEGAEN VGYFTPAQKI PAGAAIGVPQ TKLFTPLKIR GVEFHNRMFV SPMCTYSADQ
     EGHLTDFHLV HLGAMGMRGP GLVMVEATAV SPEGRISPND SGLWMESQMK PLRRIVEFAH
     SQNQKIGIQL AHAGRKASTT APYRGYTVAT EAQGGWENDV YGPNEDRWDE NHAQPHKLTE
     KQYDELVDKF VVAAKRAVEI GFDVIEIHGA HGYLISSTVS PATNDRNDKY GGTFEKRILF
     PMEVVHSVRK AIPDSMPLFY RVTATDWLPK GQGWEIEDTV ALAARLRDGG VDLIDVSSGG
     NHKDQRIEVK DCYQVPFAEK IKDQVNGILL GAVGMIRDGL TANEILESGK ADVTFVAREF
     LRNPSLVLDS ANQLGENVAW PVQYDYAVKG HRKLR
//