ID   POP7_SCHPO              Reviewed;         102 AA.
AC   O94251;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   24-JAN-2024, entry version 99.
DE   RecName: Full=Ribonucleases P/MRP protein subunit POP7;
DE            EC=3.1.26.5;
DE   AltName: Full=RNA-processing protein POP7;
GN   Name=pop7; Synonyms=pop6; ORFNames=SPBP8B7.01c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Component of ribonuclease P, a protein complex that generates
CC       mature tRNA molecules by cleaving their 5'-ends. Also a component of
CC       RNase MRP, which cleaves pre-rRNA sequences (By similarity).
CC       {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endonucleolytic cleavage of RNA, removing 5'-extranucleotides
CC         from tRNA precursor.; EC=3.1.26.5;
CC   -!- SUBUNIT: Component of nuclear RNase P and RNase MRP complexes.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the histone-like Alba family. {ECO:0000305}.
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DR   EMBL; CU329671; CAA21786.1; -; Genomic_DNA.
DR   PIR; T40795; T40795.
DR   RefSeq; NP_596508.1; NM_001022429.2.
DR   AlphaFoldDB; O94251; -.
DR   BioGRID; 277844; 2.
DR   STRING; 284812.O94251; -.
DR   PaxDb; 4896-SPBP8B7-01c-1; -.
DR   EnsemblFungi; SPBP8B7.01c.1; SPBP8B7.01c.1:pep; SPBP8B7.01c.
DR   GeneID; 2541332; -.
DR   KEGG; spo:SPBP8B7.01c; -.
DR   PomBase; SPBP8B7.01c; pop7.
DR   VEuPathDB; FungiDB:SPBP8B7.01c; -.
DR   HOGENOM; CLU_158815_0_0_1; -.
DR   InParanoid; O94251; -.
DR   OMA; KTHLIAM; -.
DR   PRO; PR:O94251; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005655; C:nucleolar ribonuclease P complex; ISO:PomBase.
DR   GO; GO:0005730; C:nucleolus; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0000172; C:ribonuclease MRP complex; EXP:PomBase.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004526; F:ribonuclease P activity; IEA:UniProtKB-EC.
DR   GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IDA:PomBase.
DR   GO; GO:0034965; P:intronic box C/D RNA processing; ISO:PomBase.
DR   GO; GO:0001682; P:tRNA 5'-leader removal; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; IDA:PomBase.
DR   Gene3D; 3.30.110.20; Alba-like domain; 1.
DR   InterPro; IPR036882; Alba-like_dom_sf.
DR   InterPro; IPR014612; Pop7/Rpp20.
DR   PANTHER; PTHR15314; RIBONUCLEASE P PROTEIN SUBUNIT P20; 1.
DR   PANTHER; PTHR15314:SF1; RIBONUCLEASE P PROTEIN SUBUNIT P20; 1.
DR   Pfam; PF12328; Rpp20; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Nucleus; Reference proteome; rRNA processing; tRNA processing.
FT   CHAIN           1..102
FT                   /note="Ribonucleases P/MRP protein subunit POP7"
FT                   /id="PRO_0000304053"
SQ   SEQUENCE   102 AA;  11843 MW;  4755FA5DB10B3B4A CRC64;
     MSVERIKRAP AFRKGIIIRR KTHLIAMIRR MRKKLDIDGS ILYQATGMAI PHLVELSDKY
     KRQGYNISMD TATVEFMDEI VDEVSIQNKN RLGNVLLLRV SR
//