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O94213

- TPS1_PICAN

UniProt

O94213 - TPS1_PICAN

Protein

Alpha,alpha-trehalose-phosphate synthase [UDP-forming]

Gene

TPS1

Organism
Pichia angusta (Yeast) (Hansenula polymorpha)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (01 May 1999)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate.

    GO - Molecular functioni

    1. alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity Source: UniProtKB-EC

    GO - Biological processi

    1. trehalose biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Protein family/group databases

    CAZyiGT20. Glycosyltransferase Family 20.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alpha,alpha-trehalose-phosphate synthase [UDP-forming] (EC:2.4.1.15)
    Alternative name(s):
    Trehalose-6-phosphate synthase
    UDP-glucose-glucosephosphate glucosyltransferase
    Gene namesi
    Name:TPS1
    OrganismiPichia angusta (Yeast) (Hansenula polymorpha)
    Taxonomic identifieri870730 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetales incertae sedisOgataea

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 475475Alpha,alpha-trehalose-phosphate synthase [UDP-forming]PRO_0000122499Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliO94213.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyltransferase 20 family.Curated

    Phylogenomic databases

    PhylomeDBiO94213.

    Family and domain databases

    InterProiIPR001830. Glyco_trans_20.
    IPR012766. Trehalose_OtsA.
    [Graphical view]
    PfamiPF00982. Glyco_transf_20. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR02400. trehalose_OtsA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    O94213-1 [UniParc]FASTAAdd to Basket

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    MVKGNVIVVS NRIPVTIKKT EDDENGKSRY DYTMSSGGLV TALQGLKNPF    50
    RWFGWPGMSV DSEQGRQTVE RDLKEKFNCY PIWLSDEIAD LHYNGFSNSI 100
    LWPLFHYHPG EMNFDEIAWA AYLEANKLFC QTILKEIKDG DVIWVHDYHL 150
    MLLPSLLRDQ LNSKGLPNVK IGFFLHTPFP SSEIYRILPV RKEILEGVLS 200
    CDLIGFHTYD YVRHFLSSVE RILKLRTSPQ GVVYNDRQVT VSAYPIGIDV 250
    DKFLNGLKTD EVKSRIKQLE TRFGKDCKLI IGVDRLDYIK GVPQKLHAFE 300
    IFLERHPEWI GKVVLIQVAV PSRGDVEEYQ SLRAAVNELV GRINGRFGTV 350
    EFVPIHFLHK SVNFQELISV YAASDVCVVS STRDGMNLVS YEYIACQQDR 400
    KGSLVLSEFA GAAQSLNGAL VVNPWNTEEL SEAIYEGLIM SEEKRRGNFQ 450
    KMFKYIEKYT ASYWGENFVK ELTRV 475
    Length:475
    Mass (Da):54,407
    Last modified:May 1, 1999 - v1
    Checksum:i14F1A07AE88E12AB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ010725 Genomic DNA. Translation: CAB38058.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ010725 Genomic DNA. Translation: CAB38058.1 .

    3D structure databases

    ProteinModelPortali O94213.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi GT20. Glycosyltransferase Family 20.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    PhylomeDBi O94213.

    Family and domain databases

    InterProi IPR001830. Glyco_trans_20.
    IPR012766. Trehalose_OtsA.
    [Graphical view ]
    Pfami PF00982. Glyco_transf_20. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR02400. trehalose_OtsA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The thermophilic yeast hansenula polymorpha does not require trehalose synthesis for growth at high temperatures but does for normal acquisition of thermotolerance."
      Reinders A., Romano I., Wiemken A., De Virgilio C.
      J. Bacteriol. 181:4665-4668(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 34438 / CBS 4732 / DSM 70277 / JCM 3621 / NBRC 1476 / NRRL Y-5445.

    Entry informationi

    Entry nameiTPS1_PICAN
    AccessioniPrimary (citable) accession number: O94213
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 6, 2002
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3