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O94213

- TPS1_PICAN

UniProt

O94213 - TPS1_PICAN

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Protein

Alpha,alpha-trehalose-phosphate synthase [UDP-forming]

Gene

TPS1

Organism
Pichia angusta (Yeast) (Hansenula polymorpha)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate.

GO - Molecular functioni

  1. alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity Source: UniProtKB-EC

GO - Biological processi

  1. trehalose biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Protein family/group databases

CAZyiGT20. Glycosyltransferase Family 20.

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] (EC:2.4.1.15)
Alternative name(s):
Trehalose-6-phosphate synthase
UDP-glucose-glucosephosphate glucosyltransferase
Gene namesi
Name:TPS1
OrganismiPichia angusta (Yeast) (Hansenula polymorpha)
Taxonomic identifieri870730 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesPichiaceaeOgataea

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 475475Alpha,alpha-trehalose-phosphate synthase [UDP-forming]PRO_0000122499Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliO94213.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 20 family.Curated

Phylogenomic databases

PhylomeDBiO94213.

Family and domain databases

InterProiIPR001830. Glyco_trans_20.
IPR012766. Trehalose_OtsA.
[Graphical view]
PfamiPF00982. Glyco_transf_20. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02400. trehalose_OtsA. 1 hit.

Sequencei

Sequence statusi: Complete.

O94213-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVKGNVIVVS NRIPVTIKKT EDDENGKSRY DYTMSSGGLV TALQGLKNPF
60 70 80 90 100
RWFGWPGMSV DSEQGRQTVE RDLKEKFNCY PIWLSDEIAD LHYNGFSNSI
110 120 130 140 150
LWPLFHYHPG EMNFDEIAWA AYLEANKLFC QTILKEIKDG DVIWVHDYHL
160 170 180 190 200
MLLPSLLRDQ LNSKGLPNVK IGFFLHTPFP SSEIYRILPV RKEILEGVLS
210 220 230 240 250
CDLIGFHTYD YVRHFLSSVE RILKLRTSPQ GVVYNDRQVT VSAYPIGIDV
260 270 280 290 300
DKFLNGLKTD EVKSRIKQLE TRFGKDCKLI IGVDRLDYIK GVPQKLHAFE
310 320 330 340 350
IFLERHPEWI GKVVLIQVAV PSRGDVEEYQ SLRAAVNELV GRINGRFGTV
360 370 380 390 400
EFVPIHFLHK SVNFQELISV YAASDVCVVS STRDGMNLVS YEYIACQQDR
410 420 430 440 450
KGSLVLSEFA GAAQSLNGAL VVNPWNTEEL SEAIYEGLIM SEEKRRGNFQ
460 470
KMFKYIEKYT ASYWGENFVK ELTRV
Length:475
Mass (Da):54,407
Last modified:May 1, 1999 - v1
Checksum:i14F1A07AE88E12AB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ010725 Genomic DNA. Translation: CAB38058.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ010725 Genomic DNA. Translation: CAB38058.1 .

3D structure databases

ProteinModelPortali O94213.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

CAZyi GT20. Glycosyltransferase Family 20.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

PhylomeDBi O94213.

Family and domain databases

InterProi IPR001830. Glyco_trans_20.
IPR012766. Trehalose_OtsA.
[Graphical view ]
Pfami PF00982. Glyco_transf_20. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR02400. trehalose_OtsA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The thermophilic yeast hansenula polymorpha does not require trehalose synthesis for growth at high temperatures but does for normal acquisition of thermotolerance."
    Reinders A., Romano I., Wiemken A., De Virgilio C.
    J. Bacteriol. 181:4665-4668(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 34438 / CBS 4732 / DSM 70277 / JCM 3621 / NBRC 1476 / NRRL Y-5445.

Entry informationi

Entry nameiTPS1_PICAN
AccessioniPrimary (citable) accession number: O94213
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 6, 2002
Last sequence update: May 1, 1999
Last modified: October 29, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3