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O94213 (TPS1_PICAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Alpha,alpha-trehalose-phosphate synthase [UDP-forming]

EC=2.4.1.15
Alternative name(s):
Trehalose-6-phosphate synthase
UDP-glucose-glucosephosphate glucosyltransferase
Gene names
Name:TPS1
OrganismPichia angusta (Yeast) (Hansenula polymorpha)
Taxonomic identifier870730 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetales incertae sedisOgataea

Protein attributes

Sequence length475 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate.

Sequence similarities

Belongs to the glycosyltransferase 20 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 475475Alpha,alpha-trehalose-phosphate synthase [UDP-forming]
PRO_0000122499

Sequences

Sequence LengthMass (Da)Tools
O94213 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: 14F1A07AE88E12AB

FASTA47554,407
        10         20         30         40         50         60 
MVKGNVIVVS NRIPVTIKKT EDDENGKSRY DYTMSSGGLV TALQGLKNPF RWFGWPGMSV 

        70         80         90        100        110        120 
DSEQGRQTVE RDLKEKFNCY PIWLSDEIAD LHYNGFSNSI LWPLFHYHPG EMNFDEIAWA 

       130        140        150        160        170        180 
AYLEANKLFC QTILKEIKDG DVIWVHDYHL MLLPSLLRDQ LNSKGLPNVK IGFFLHTPFP 

       190        200        210        220        230        240 
SSEIYRILPV RKEILEGVLS CDLIGFHTYD YVRHFLSSVE RILKLRTSPQ GVVYNDRQVT 

       250        260        270        280        290        300 
VSAYPIGIDV DKFLNGLKTD EVKSRIKQLE TRFGKDCKLI IGVDRLDYIK GVPQKLHAFE 

       310        320        330        340        350        360 
IFLERHPEWI GKVVLIQVAV PSRGDVEEYQ SLRAAVNELV GRINGRFGTV EFVPIHFLHK 

       370        380        390        400        410        420 
SVNFQELISV YAASDVCVVS STRDGMNLVS YEYIACQQDR KGSLVLSEFA GAAQSLNGAL 

       430        440        450        460        470 
VVNPWNTEEL SEAIYEGLIM SEEKRRGNFQ KMFKYIEKYT ASYWGENFVK ELTRV 

« Hide

References

[1]"The thermophilic yeast hansenula polymorpha does not require trehalose synthesis for growth at high temperatures but does for normal acquisition of thermotolerance."
Reinders A., Romano I., Wiemken A., De Virgilio C.
J. Bacteriol. 181:4665-4668(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 34438 / CBS 4732 / DSM 70277 / JCM 3621 / NBRC 1476 / NRRL Y-5445.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ010725 Genomic DNA. Translation: CAB38058.1.

3D structure databases

ProteinModelPortalO94213.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGT20. Glycosyltransferase Family 20.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

PhylomeDBO94213.

Family and domain databases

InterProIPR001830. Glyco_trans_20.
IPR012766. Trehalose_OtsA.
[Graphical view]
PfamPF00982. Glyco_transf_20. 1 hit.
[Graphical view]
TIGRFAMsTIGR02400. trehalose_OtsA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTPS1_PICAN
AccessionPrimary (citable) accession number: O94213
Entry history
Integrated into UniProtKB/Swiss-Prot: June 6, 2002
Last sequence update: May 1, 1999
Last modified: July 9, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families