O94178 (SODC_COLGL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Superoxide dismutase [Cu-Zn]
EC=1.15.1.1

Gene names

Name:

SOD1

Organism

Colletotrichum gloeosporioides (Anthracnose fungus) (Glomerella cingulata)

Taxonomic identifier

474922 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Sordariomycetes › Hypocreomycetidae › Glomerellales › Glomerellaceae › Glomerella

Protein attributes

Sequence length	154 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity.
Catalytic activity	2 superoxide + 2 H+ = O2 + H2O2.
Cofactor	Binds 1 copper ion per subunit By similarity. Binds 1 zinc ion per subunit By similarity.
Subunit structure	Homodimer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the Cu-Zn superoxide dismutase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Copper Metal-binding Zinc
Molecular function	Antioxidant Oxidoreductase
PTM	Disulfide bond
Gene Ontology (GO)
Biological process	superoxide metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW superoxide dismutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 154	153	Superoxide dismutase [Cu-Zn]		PRO_0000164115
Sites
	Metal binding	47	1	Copper By similarity
	Metal binding	49	1	Copper By similarity
	Metal binding	64	1	Copper By similarity
	Metal binding	64	1	Zinc By similarity
	Metal binding	72	1	Zinc By similarity
	Metal binding	81	1	Zinc By similarity
	Metal binding	84	1	Zinc By similarity
	Metal binding	121	1	Copper By similarity
Amino acid modifications
	Disulfide bond	58 ↔ 147		By similarity

Sequences

	Sequence		Length	Mass (Da)
	O94178 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: 177F4962166699AC	FASTA	154	15,966
	10 20 30 40 50 60 MVKAVCVVRG DSKVTGSIVF EQESESAPTK ITWDISGNDA NAKRGMHIHT FGDNTNGCTS 70 80 90 100 110 120 AGPHFNPHNK THGAPEDSNR HVGDLGNIET DANGNSKGTV TDSHVKLIGP ESVIGRTIVV 130 140 150 HGGTDDLGKG DNEESLKTGN AGPRPACGVI GISN

References

[1]	"A Cu-Zn superoxide dismutase from Glomerella cingulata." Clark S.J., Templeton M.D., Sullivan P.A. Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ICMP 110146.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF076951 Genomic DNA. Translation: AAD19338.1.
3D structure databases
ProteinModelPortal	O94178.
SMR	O94178. Positions 2-154.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR024134. SOD_Cu/Zn_/chaperones. IPR018152. SOD_Cu/Zn_BS. IPR001424. SOD_Cu_Zn_dom. [Graphical view]
Gene3D	G3DSA:2.60.40.200. SOD_Cu_Zn. 1 hit.
PANTHER	PTHR10003. SOD_Cu_Zn. 1 hit.
Pfam	PF00080. Sod_Cu. 1 hit. [Graphical view]
PRINTS	PR00068. CUZNDISMTASE.
SUPFAM	SSF49329. SOD_Cu_Zn. 1 hit.
PROSITE	PS00087. SOD_CU_ZN_1. 1 hit. PS00332. SOD_CU_ZN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SODC_COLGL

Accession

Primary (citable) accession number: O94178

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 31, 2004
Last sequence update:	January 23, 2007
Last modified:	July 27, 2011
This is version 58 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program