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O94095 (ALTA2_ALTAL) Reviewed, UniProtKB/Swiss-Prot

Last modified September 18, 2013. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Allergen Alt a 2
Alternative name(s):
Allergen=Alt a 2
Gene names
Name:ALTA2
OrganismAlternaria alternata (Alternaria rot fungus) (Torula alternata)
Taxonomic identifier5599 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaDothideomycetesPleosporomycetidaePleosporalesPleosporineaePleosporaceaeAlternariaAlternaria alternata group

Protein attributes

Sequence length190 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Allergenic properties

Causes an allergic reaction in human. Binds to IgE. Ref.2

Caution

Was originally (Ref.1) identified to be a major allergen, but a second study (Ref.2) reported a very low prevalence.

Ontologies

Keywords
   DiseaseAllergen
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 190190Allergen Alt a 2
PRO_0000345087

Sequences

Sequence LengthMass (Da)Tools
O94095 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: 4A2867362792C72A

FASTA19022,387
        10         20         30         40         50         60 
MHSSNNFFKD NIFRSLSKED PDYSRNIEGQ VIRLHWDWAQ LLMLSAKRMK VAFKLDIEKD 

        70         80         90        100        110        120 
QRVWDRCTAD DLKGRNGFKR CLQFTLYRPR DLLSLLNEAF FSAFRENRET IINTDLEYAA 

       130        140        150        160        170        180 
KSISMARLED LWKEYQKIFP SIQVITSAFR SIEPELTVYT CLKKIEASFE LIEENGDPKI 

       190 
TSEIQLLKAS 

« Hide

References

[1]"Molecular cloning of a major Alternaria alternata allergen, rAlt a 2."
Bush R.K., Sanchez H., Geisler D.
J. Allergy Clin. Immunol. 104:665-671(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], IGE-BINDING.
Strain: ATCC 46582 / PD 1.
[2]"Diagnosis of Alternaria alternata sensitization with natural and recombinant Alt a 1 allergens."
Asturias J.A., Ibarrola I., Ferrer A., Andreu C., Lopez-Pascual E., Quiralte J., Florido F., Martinez A.
J. Allergy Clin. Immunol. 115:1210-1217(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: ALLERGEN.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U62442 mRNA. Translation: AAD00097.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein family/group databases

Allergome16. Alt a 2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameALTA2_ALTAL
AccessionPrimary (citable) accession number: O94095
Entry history
Integrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: May 1, 1999
Last modified: September 18, 2013
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Allergens

Nomenclature of allergens and list of entries