O93980 (COX5_ASPNG) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytochrome c oxidase polypeptide 5, mitochondrial
EC=1.9.3.1

Alternative name(s):
Cytochrome c oxidase polypeptide V

Gene names

Name:

cox5

Organism

Aspergillus niger

Taxonomic identifier

5061 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus

Protein attributes

Sequence length	197 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.
Subunit structure	Composed of at least 11 subunits By similarity.
Subcellular location	Mitochondrion inner membrane By similarity.
Sequence similarities	Belongs to the cytochrome c oxidase IV family.

Ontologies

Keywords
Cellular component	Membrane Mitochondrion Mitochondrion inner membrane
Domain	Transit peptide
Molecular function	Oxidoreductase
Gene Ontology (GO)
Cellular_component	mitochondrial inner membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	cytochrome-c oxidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – 52	52	Mitochondrion Potential
	Chain	53 – 197	145	Cytochrome c oxidase polypeptide 5, mitochondrial		PRO_0000006094

Sequences

	Sequence		Length	Mass (Da)
	O93980 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: ED41386462784E34	FASTA	197	22,250
	10 20 30 40 50 60 MFLRSVTRAA ARSSAVPTTG LRSYRTVSGP MACLNARPQT EKKSIAPQQT RAASEHAISN 70 80 90 100 110 120 PTLAGIEKRW EAMPPQEQAE LWMQLRDRMK VDWHQMTLQE KKAAYWISFG PHGPRSVPPK 130 140 150 160 170 180 GENLKIFFKV AQLTLVSFGI FYVIHLFAKP QPKTMTKEWQ EASNEYAKQE KINPIYGISA 190 EGYEGKGFVQ SPPAEKQ

References

[1]	"Promoter-tagged restriction enzyme-mediated insertion (PT-REMI) mutagenesis in Aspergillus niger." Shuster J.R., Connelley M.B. Mol. Gen. Genet. 262:27-34(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ132229 Genomic DNA. Translation: CAA10609.1.
3D structure databases
ProteinModelPortal	O93980.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
eggNOG	NOG263759.
Family and domain databases
Gene3D	1.10.442.10. 1 hit.
InterPro	IPR004203. Cyt_c_oxidase_su4_fam. [Graphical view]
Pfam	PF02936. COX4. 1 hit. [Graphical view]
SUPFAM	SSF81406. COX4. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COX5_ASPNG

Accession

Primary (citable) accession number: O93980

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 3, 2002
Last sequence update:	May 1, 1999
Last modified:	April 3, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program