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O93939

- EXG1_HANAN

UniProt

O93939 - EXG1_HANAN

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Protein

Glucan 1,3-beta-glucosidase 1

Gene

EXG1

Organism
Hansenula anomala (Yeast) (Candida pelliculosa)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. It could also function biosynthetically as a transglycosylase (By similarity).By similarity

Catalytic activityi

Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1->3)-beta-D-glucans, releasing alpha-glucose.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei218 – 2181Proton donorBy similarity
Active sitei341 – 3411NucleophileBy similarity

GO - Molecular functioni

  1. glucan exo-1,3-beta-glucosidase activity Source: UniProtKB-EC

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
  2. cell wall organization Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Cell wall biogenesis/degradation

Protein family/group databases

CAZyiGH5. Glycoside Hydrolase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucan 1,3-beta-glucosidase 1 (EC:3.2.1.58)
Alternative name(s):
Exo-1,3-beta-glucanase 1
Gene namesi
Name:EXG1
OrganismiHansenula anomala (Yeast) (Candida pelliculosa)
Taxonomic identifieri4927 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesPhaffomycetaceaeWickerhamomyces

Subcellular locationi

Secreted Curated

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818Sequence AnalysisAdd
BLAST
Chaini19 – 498480Glucan 1,3-beta-glucosidase 1PRO_0000007882Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi349 ↔ 394By similarity

Keywords - PTMi

Disulfide bond, Zymogen

Structurei

3D structure databases

ProteinModelPortaliO93939.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001547. Glyco_hydro_5.
IPR018087. Glyco_hydro_5_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF00150. Cellulase. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiPS00659. GLYCOSYL_HYDROL_F5. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O93939-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLFNILILSA LSLQLCTCFH IKRNLNGSND VIWDYYDDSK KVQGVSLGGW
60 70 80 90 100
FVLEPYITPS LFEQFGEDEK KIPVDEYTFT EQLGKDEAQK QLDKHWATYF
110 120 130 140 150
TESDFKDIKD YGLNLVRIPI GYWAFYLLED DPYVQGQEPY LDKALEWAKQ
160 170 180 190 200
NDLKVWIDLH GVPGSQNGFD NSGKRGNVTW QDDEENIELS YKTLNYIFGK
210 220 230 240 250
YGGENLTDTV IGIEIVNEPF HSKLNETDML DFYYNSYYDF RIKHNSRNFF
260 270 280 290 300
LIQEAFEPIG FWNTHLNNDY TNVSKPFLND ELLEEGVPKN YFHDIVLDHH
310 320 330 340 350
HYEVFSVDQL DKSENARIQD IKNYGESVAK EQEYHPSLVG EWSGAITDCA
360 370 380 390 400
KWLNGVGTGA RYDGTFDESQ LVRTNAINGT AESQFKFKDK KRSCENVTFV
410 420 430 440 450
EDFSKQHKEN IRKFIEIQLL TYENSNSGWI FWNYKTENAI EWDFKKLVEH
460 470 480 490
KLFPHPFNEY KYFYENGTQI VESAASGNPQ NLLFITLSAL LVSLSTLL
Length:498
Mass (Da):58,063
Last modified:May 1, 1999 - v1
Checksum:i04B129CAD6ED6D31
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ002195 Genomic DNA. Translation: CAA05243.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ002195 Genomic DNA. Translation: CAA05243.1 .

3D structure databases

ProteinModelPortali O93939.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

CAZyi GH5. Glycoside Hydrolase Family 5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.20.20.80. 1 hit.
InterProi IPR001547. Glyco_hydro_5.
IPR018087. Glyco_hydro_5_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
Pfami PF00150. Cellulase. 1 hit.
[Graphical view ]
SUPFAMi SSF51445. SSF51445. 1 hit.
PROSITEi PS00659. GLYCOSYL_HYDROL_F5. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Preliminary study of exo-beta-1,3-glucanase genes in relation to the protective activity of Pichia anomala (strain K) against Botrytis cinerea on postharvest apples."
    Grevesse C., Jijakli M.H., Duterme O., Colinet D., Lepoivre P.
    Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K.

Entry informationi

Entry nameiEXG1_HANAN
AccessioniPrimary (citable) accession number: O93939
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: May 1, 1999
Last modified: October 29, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3