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O93864 (PYRF_PACTA) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Orotidine 5'-phosphate decarboxylase

EC=4.1.1.23
Alternative name(s):
OMP decarboxylase
Short name=OMPDCase
Short name=OMPdecase
Uridine 5'-monophosphate synthase
Short name=UMP synthase
Gene names
Name:URA3
OrganismPachysolen tannophilus (Yeast)
Taxonomic identifier4918 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaePachysolen

Protein attributes

Sequence length268 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Orotidine 5'-phosphate = UMP + CO2.

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.

Sequence similarities

Belongs to the OMP decarboxylase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 268268Orotidine 5'-phosphate decarboxylase
PRO_0000134666

Regions

Region61 – 633Substrate binding By similarity
Region93 – 10210Substrate binding By similarity

Sites

Active site951Proton donor By similarity
Binding site391Substrate By similarity
Binding site2191Substrate By similarity
Binding site2371Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
O93864 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: ECC89602DA2FC10A

FASTA26829,684
        10         20         30         40         50         60 
MAVLDVSYGE RAKVHASPVA RRLFELMEKK QSNLCASIDV SSTDELLKLV EKLGPVICLV 

        70         80         90        100        110        120 
KTHIDTIDDF SYDGTILPLV ELSKKYNFMI FEDRKFADIG NTVKNQYKNG IFKIAQWADI 

       130        140        150        160        170        180 
TNAHGVTGEG IVKGLKEAAL ETTLEPRGLL MLAELSSKGS LAYGEYTNKT VEIAKSDKDF 

       190        200        210        220        230        240 
VIGFIAQHDM GGREEGFDWI IMTPGVGLDD KGDKLGQQYR TVDQVIDSGS DIIIVGRGLF 

       250        260 
GKGRDPVLQG ERYRKAGWDA YLKRIGQL 

« Hide

References

[1]Clark-Walker G.D.
Submitted (FEB-1998) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF047170 Genomic DNA. Translation: AAD02431.1.

3D structure databases

ProteinModelPortalO93864.
SMRO93864. Positions 7-267.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00070; UER00120.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
InterProIPR013785. Aldolase_TIM.
IPR014732. OMPdecase.
IPR018089. OMPdecase_AS.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
TIGRFAMsTIGR01740. pyrF. 1 hit.
PROSITEPS00156. OMPDECASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePYRF_PACTA
AccessionPrimary (citable) accession number: O93864
Entry history
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: May 1, 1999
Last modified: October 16, 2013
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways