Reviewed,
UniProtKB/Swiss-Prot O93852 (ALO_CANAL)
Last modified
June 16, 2009.
Version 57.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
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Names and origin
| Protein names | Recommended name: D-arabinono-1,4-lactone oxidase Short name=ALO EC=1.1.3.37 Alternative name(s): L-galactono-gamma-lactone oxidase | ||||||
| Gene names |
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| Organism | Candida albicans (Yeast) | ||||||
| Taxonomic identifier | 5476 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida |
Protein attributes
| Sequence length | 557 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H2O2. |
| Cofactor | FAD. |
| Pathway | |
| Subcellular location | Mitochondrion membrane By similarity. Note: Membrane-embedded By similarity. |
| Sequence similarities | Belongs to the oxygen-dependent FAD-linked oxidoreductase family. Contains 1 FAD-binding PCMH-type domain. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Virulence |
| Cellular component | Membrane Mitochondrion |
| Ligand | FAD Flavoprotein |
| Molecular function | Oxidoreductase |
| Gene Ontology (GO) | |
| Biological process | biosynthetic process Inferred from electronic annotation. Source: InterPro oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW pathogenesisInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | mitochondrial membrane Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | D-arabinono-1,4-lactone oxidase activity Inferred from electronic annotation. Source: EC FAD bindingInferred from electronic annotation. Source: InterPro electron carrier activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Deficiency of D-erythroascorbic acid attenuates hyphal growth and virulence of Candida albicans." Huh W.-K., Kim S.-T., Kim H., Jeong G., Kang S.-O. Infect. Immun. 69:3939-3946(2001) [PubMed: 11349062] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 10231 / CBS 6431 / DSM 1386 / IFO 1594. |
| [2] | "The diploid genome sequence of Candida albicans." Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S. Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed: 15123810] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC5314. |
Cross-references
Sequence databases | |
|---|---|
| AF031228 Genomic DNA. Translation: AAC98913.1. AACQ01000032 Genomic DNA. Translation: EAL00425.1. | |
| RefSeq | XP_719313.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 3638983. |
Organism-specific databases | |
| CGD | CAL0000083. ALO1. |
Phylogenomic databases | |
| OMA | O93852. DCLFSQF. |
Enzyme and pathway databases | |
| BRENDA | 1.1.3.37. 1124. |
Family and domain databases | |
| InterPro | IPR007173. ALO. IPR016166. FAD-bd_2. IPR010031. FAD_lactone_oxidase. IPR006094. Oxid_FAD_bind_N. IPR006093. Oxy_OxRdtase_FAD_BS. [Graphical view] |
| Pfam | PF04030. ALO. 1 hit. PF01565. FAD_binding_4. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR01678. FAD_lactone_ox. 1 hit. |
| PROSITE | PS51387. FAD_PCMH. 1 hit. PS00862. OX2_COVAL_FAD. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | ALO_CANAL | ||||||||
| Accession | Primary (citable) accession number: O93852 Secondary accession number(s): Q5ACU1 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| Candida albicans Candida albicans: entries and gene names |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


