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Protein
Submitted name:

F420-dependent alcohol dehydrogenase

Gene

adf

Organism
Methanoculleus thermophilus
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei39 – 391Proton donor/acceptorCombined sources
Sitei43 – 431Transition state stabilizerCombined sources
Sitei108 – 1081Important for catalytic activityCombined sources

GO - Molecular functioni

Complete GO annotation...

Enzyme and pathway databases

BRENDAi1.1.98.5. 3272.

Names & Taxonomyi

Protein namesi
Submitted name:
F420-dependent alcohol dehydrogenaseImported
Gene namesi
Name:adfImported
OrganismiMethanoculleus thermophilusImported
Taxonomic identifieri2200 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanomicrobiaceaeMethanoculleus

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1RHCX-ray1.80A1-330[»]
ProteinModelPortaliO93734.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO93734.

Family & Domainsi

Family and domain databases

Gene3Di3.20.20.30. 1 hit.
InterProiIPR019945. F420_G6P_DH-rel.
IPR011251. Luciferase-like_dom.
[Graphical view]
PfamiPF00296. Bac_luciferase. 1 hit.
[Graphical view]
SUPFAMiSSF51679. SSF51679. 1 hit.
TIGRFAMsiTIGR03557. F420_G6P_family. 1 hit.

Sequencei

Sequence statusi: Fragment.

O93734-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTQIGYFAS LEQYRPMDAL EQAIRAEKVG FDSVWVDDHF HPWYHDNAQS
60 70 80 90 100
AQAWAWMGAA LQATKKVFIS TCITCPIMRY NPAIVAQTFA TLRQMYPGRV
110 120 130 140 150
GVAVGAGEAM NEVPVTGEWP SVPVRQDMTV EAVKVMRMLW ESDKPVTFKG
160 170 180 190 200
DYFTLDKAFL YTKPDDEVPL YFSGMGPKGA KLAGMYGDHL MTVAAAPSTL
210 220 230 240 250
KNVTIPKFEE GAREAGKDPS KMEHAMLIWY SVDPDYDKAV EALRFWAGCL
260 270 280 290 300
VPSMFKYKVY DPKEVQLHAN LVHCDTIKEN YMCATDAEEM IKEIERFKEA
310 320 330
GINHFCLGNS SPDVNFGIDI FKEVIPAVRD
Length:330
Mass (Da):37,158
Last modified:May 1, 1999 - v1
Checksum:iCD1528E3B0AF11EB
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei330 – 3301Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y18729 Genomic DNA. Translation: CAA77275.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y18729 Genomic DNA. Translation: CAA77275.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1RHCX-ray1.80A1-330[»]
ProteinModelPortaliO93734.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

BRENDAi1.1.98.5. 3272.

Miscellaneous databases

EvolutionaryTraceiO93734.

Family and domain databases

Gene3Di3.20.20.30. 1 hit.
InterProiIPR019945. F420_G6P_DH-rel.
IPR011251. Luciferase-like_dom.
[Graphical view]
PfamiPF00296. Bac_luciferase. 1 hit.
[Graphical view]
SUPFAMiSSF51679. SSF51679. 1 hit.
TIGRFAMsiTIGR03557. F420_G6P_family. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Berk H., Thauer R.K.
    Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Coenzyme binding in F420-dependent secondary alcohol dehydrogenase, a member of the bacterial luciferase family."
    Aufhammer S.W., Warkentin E., Berk H., Shima S., Thauer R.K., Ermler U.
    Structure 12:361-370(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS), ACTIVE SITE.

Entry informationi

Entry nameiO93734_9EURY
AccessioniPrimary (citable) accession number: O93734
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: June 24, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.