Reviewed, UniProtKB/Swiss-Prot O93662 (CATA_METBF)

Names and origin

Protein names

Recommended name:
    Catalase
    EC=1.11.1.6

Gene names

Name:	kat
Ordered Locus Names:	Mbar_A0814

Organism

Methanosarcina barkeri (strain Fusaro / DSM 804) [Complete proteome] [HAMAP]

Taxonomic identifier

269797 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosarcinaceae › Methanosarcina

Protein attributes

Sequence length	505 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
Catalytic activity	2 H(2)O(2) = O(2) + 2 H(2)O.
Cofactor	Heme group By similarity.
Sequence similarities	Belongs to the catalase family.

Ontologies

Keywords
Biological process	Hydrogen peroxide
Ligand	Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	catalase activity Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 505	505	Catalase		PRO_0000085019
Sites
	Active site	58	1	By similarity
	Active site	131	1	By similarity
	Metal binding	341	1	Iron (heme axial ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	O93662-1 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 2A27C4BEC47BE854	FASTA	505	57,066
	10 20 30 40 50 60 MGEKNSSKVL TTGFGIPVGD DQNSLTAGNR GPVLMQDVHL LDKLSHFDHE RIPERVVHAK 70 80 90 100 110 120 GAGAGGYFEV TADVTKYTKA KFLSEIGKRT EVFVRFSTVG GEKGSADSAR DPRGFAVKFY 130 140 150 160 170 180 TEDGNYDLVG NNTPVFFIRD PLKFPDFIHT QKRNPATNCK DPDMFWDFLS LTPESIHQVT 190 200 210 220 230 240 ILFSDRGTPA TYRNMNGYSS HTYKWYNEKG EYFWVQYHFK TDQGIKNLTL EEAEKIGGSD 250 260 270 280 290 300 PDHATRDLYE AIKKGDYPSW TLEMQIMTPE QAEDYRFDIR DITKVWPHGD FPTMKIGKLV 310 320 330 340 350 360 LNRNPTNYFA EVEQAAFSPA NLVPGIGISP DKMLQGRVFS YHDTHIHRLG PNYNLIPVNA 370 380 390 400 410 420 PKYSPENSYQ RDGFMRVDAN GGSGPNYWPN SFGGPSPDSV YLEPPFGVSG LAARTLYTHP 430 440 450 460 470 480 NDDFVQAGNL YRDVMTDYDR ENLVGNIVSH LSAAQKRIQL RQTALFFKAD RDYGSRVAKG 490 500 LELDIKEVER LANMTNEERA RATER

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Purification, characterization, and primary structure of a monofunctional catalase from Methanosarcina barkeri." Shima S., Netrusov A., Sordel M., Wicke M., Hartmann G.C., Thauer R.K. Arch. Microbiol. 171:317-323(1999) [PubMed: 10382262] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"The Methanosarcina barkeri genome: comparative analysis with Methanosarcina acetivorans and Methanosarcina mazei reveals extensive rearrangement within methanosarcinal genomes." Maeder D.L., Anderson I., Brettin T.S., Bruce D.C., Gilna P., Han C.S., Lapidus A., Metcalf W.W., Saunders E., Tapia R., Sowers K.R. J. Bacteriol. 188:7922-7931(2006) [PubMed: 16980466] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ005939 Genomic DNA. Translation: CAA06774.1. CP000099 Genomic DNA. Translation: AAZ69791.1.
RefSeq	YP_304371.1.
3D structure databases
HSSP	HSSP built from PDB template 1F4J based on UniProtKB P04040.
ModBase	Search...
Genome annotation databases
GeneID	3626836.
GenomeReviews	Gene locus Mbar_A0814 in contig CP000099_GR.
KEGG	mba:Mbar_A0814.
NMPDR	fig|269797.3.peg.254.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	O93662.
Enzyme and pathway databases
BioCyc	MBAR269797:MBAR_A0814-MON.
Family and domain databases
InterPro	IPR002226. Catalase. IPR011614. Catalase_N. [Graphical view]
Gene3D	G3DSA:2.40.180.10. Catalase_N. 1 hit.
PANTHER	PTHR11465. Catalase. 1 hit.
Pfam	PF00199. Catalase. 1 hit. [Graphical view]
PRINTS	PR00067. CATALASE.
ProDom	PD000510. Catalase. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00437. CATALASE_1. 1 hit. PS00438. CATALASE_2. 1 hit. PS51402. CATALASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CATA_METBF

Accession

Primary (citable) accession number: O93662
Secondary accession number(s): Q46EA1

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	May 1, 1999
Last modified:	November 25, 2008
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)