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Protein
Submitted name:

ALX homeobox 4

Gene

Alx-4

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi192 – 251HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental proteinPROSITE-ProRule annotationSAAS annotation, DNA-bindingPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
ALX homeobox 4Imported
Submitted name:
Paired type homeodomain proteinImported
Gene namesi
Name:Alx-4Imported
Synonyms:ALX4Imported
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSGALG00000025875.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000013005.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini190 – 250HomeoboxInterPro annotationAdd BLAST61
Domaini367 – 380OARInterPro annotationAdd BLAST14

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi367 – 380OARPROSITE-ProRule annotationAdd BLAST14

Sequence similaritiesi

Belongs to the paired homeobox family.SAAS annotation

Keywords - Domaini

HomeoboxPROSITE-ProRule annotationSAAS annotationImported

Phylogenomic databases

eggNOGiKOG0490. Eukaryota.
ENOG410YIJ3. LUCA.
GeneTreeiENSGT00900000140809.
HOGENOMiHOG000231518.
HOVERGENiHBG004214.
OMAiHMGQTHM.
OrthoDBiEOG091G0B1L.
TreeFamiTF350743.

Family and domain databases

CDDicd00086. homeodomain. 1 hit.
InterProiView protein in InterPro
IPR033203. ALX4.
IPR009057. Homeobox-like_sf.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR003654. OAR_dom.
PANTHERiPTHR24329:SF322. PTHR24329:SF322. 1 hit.
PfamiView protein in Pfam
PF00046. Homeobox. 1 hit.
PF03826. OAR. 1 hit.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS50803. OAR. 1 hit.

Sequencei

Sequence statusi: Complete.

O93582-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNADTCVSYC DPAAMDSYYN AASQGADGSS PFRAFQASDK FGPAFLAAKG
60 70 80 90 100
QSFGDSGAKC RSRYSPQECP SLDGSGQAPG PAAPPPAFSK YPQPQQQPPH
110 120 130 140 150
LYMQRGPCKT PPESNLKLQE SGGHNGALQV SCYGKESSLG EADLQPNADP
160 170 180 190 200
SGMDSSYLSV KEAGVKVPQD RASTDLPSPM DKADSESNKG KKRRNRTTFT
210 220 230 240 250
SYQLEELEKV FQKTHYPDVY AREQLAMRTD LTEARVQVWF QNRRAKWRKR
260 270 280 290 300
ERFGQMQQVR THFSTAYELP LLTRAENYAQ IQNPSWIGNN GAASPVPACV
310 320 330 340 350
VPCEPVPSCM SPHAHPHAAG GVSDFLGVSS TGGHVGQTHV GGLFGTAGIG
360 370 380
PSLNGYELNS EPDRKSSSIA ALRMKAKEHS AAISWAT
Length:387
Mass (Da):41,738
Last modified:November 1, 1998 - v1
Checksum:i614074EB1EB84207
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN04000062 Genomic DNA. No translation available.
AF092538 mRNA. Translation: AAC61772.1.
RefSeqiNP_989493.1. NM_204162.1.
UniGeneiGga.934.

Genome annotation databases

EnsembliENSGALT00000066583; ENSGALP00000050037; ENSGALG00000032584.
GeneIDi373976.

Similar proteinsi

Entry informationi

Entry nameiO93582_CHICK
AccessioniPrimary (citable) accession number: O93582
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: November 22, 2017
This is version 144 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported