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Protein
Submitted name:

IKAROS family zinc finger 1 (Ikaros)

Gene

ikzf1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • B cell differentiation Source: ZFIN
  • T cell differentiation in thymus Source: ZFIN
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
IKAROS family zinc finger 1 (Ikaros)Imported
Submitted name:
IkarosImported
Gene namesi
Name:ikzf1Imported
Synonyms:znfn1a1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-980526-304. ikzf1.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000013960.

Structurei

3D structure databases

ProteinModelPortaliO93581.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini123 – 15028C2H2-typeInterPro annotationAdd
BLAST
Domaini162 – 18928C2H2-typeInterPro annotationAdd
BLAST
Domaini190 – 21728C2H2-typeInterPro annotationAdd
BLAST
Domaini218 – 24124C2H2-typeInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOVERGENiHBG004752.
KOiK09220.
PhylomeDBiO93581.

Family and domain databases

Gene3Di3.30.160.60. 3 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 1 hit.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 6 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 5 hits.
PS50157. ZINC_FINGER_C2H2_2. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O93581-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METEEAQEMS QITGRDSPMN ANEGGEDQDE AMPVPEDLSA STGLQHNNRT
60 70 80 90 100
DKPLACNIKV EARSDEENGL SCEMNGEAEE CAAEDLRILD GSGAKVNGSH
110 120 130 140 150
AGPDSKPAAY PTAGGIRLPN GKLKCDICGI VCIGPNVLMV HKRSHTEERK
160 170 180 190 200
SVLEQQKGER PFQCNQCGAS FTQKGNLLRH IKLHSGEKPF KCHLCNYACR
210 220 230 240 250
RRDALTGHLR THSVGKPHKC AYCGRSYKQR SSLEEHKERC HNYLQCMGLQ
260 270 280 290 300
NSIYTVKEEN SQNEQREDMP ASERALVLDR IANNVAKRKS SMPQRFVGEN
310 320 330 340 350
RLSELSFESG SGELMQPHVI DQAINSAISY LGAESLRPLV QTSPGSADMV
360 370 380 390 400
VSPLYNLHKS QTAEGNGVSA KDSAAEHLLL LSKSKSASVD KDGSPSPSGQ
410 420 430 440 450
DSTDTESNNE ERSAGVSGTA ATGGLIYLTN HMAPGMRNGG LPGVKEEQQR
460 470 480 490 500
HFEALRAAGM DLSIASSEGF KVLSGDGEEL RAYRCIHCRV LFLDHVMYTI
510 520 530
HMGCHGFRDP FECNLCGYRS QDRYEFSSHI TRGEHRI
Length:537
Mass (Da):58,866
Last modified:November 1, 1998 - v1
Checksum:i3BF047938CF38A37
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF092175 mRNA. Translation: AAC61763.1.
BC162270 mRNA. Translation: AAI62270.1.
RefSeqiNP_571061.1. NM_130986.1.
UniGeneiDr.8122.

Genome annotation databases

GeneIDi30177.
KEGGidre:30177.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF092175 mRNA. Translation: AAC61763.1.
BC162270 mRNA. Translation: AAI62270.1.
RefSeqiNP_571061.1. NM_130986.1.
UniGeneiDr.8122.

3D structure databases

ProteinModelPortaliO93581.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000013960.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi30177.
KEGGidre:30177.

Organism-specific databases

CTDi10320.
ZFINiZDB-GENE-980526-304. ikzf1.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOVERGENiHBG004752.
KOiK09220.
PhylomeDBiO93581.

Family and domain databases

Gene3Di3.30.160.60. 3 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 1 hit.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 6 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 5 hits.
PS50157. ZINC_FINGER_C2H2_2. 4 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Characterization of zebrafish ikaros, a gene necessary for differentiation of the immune system."
    Amemiya C., Kawasaki H.
    Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: SpleenImported.
  2. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiO93581_DANRE
AccessioniPrimary (citable) accession number: O93581
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: June 8, 2016
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.