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Protein
Submitted name:

Paraxial protocadherin

Gene

pcdh8

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

CalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Paraxial protocadherinImported
Gene namesi
Name:pcdh8Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-980526-242. pcdh8.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei689 – 71325HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence analysisAdd
BLAST
Chaini20 – 950931Sequence analysisPRO_5004160899Add
BLAST

Proteomic databases

PaxDbiO93508.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000112237.

Structurei

3D structure databases

ProteinModelPortaliO93508.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini28 – 12598CadherinInterPro annotationAdd
BLAST
Domaini126 – 234109CadherinInterPro annotationAdd
BLAST
Domaini235 – 342108CadherinInterPro annotationAdd
BLAST
Domaini357 – 45397CadherinInterPro annotationAdd
BLAST
Domaini454 – 564111CadherinInterPro annotationAdd
BLAST
Domaini570 – 685116CadherinInterPro annotationAdd
BLAST

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3594. Eukaryota.
ENOG410XQHI. LUCA.
HOGENOMiHOG000220892.
HOVERGENiHBG054878.
KOiK16499.
PhylomeDBiO93508.

Family and domain databases

Gene3Di2.60.40.60. 6 hits.
InterProiIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
IPR013164. Cadherin_N.
[Graphical view]
PfamiPF00028. Cadherin. 5 hits.
PF08266. Cadherin_2. 1 hit.
[Graphical view]
PRINTSiPR00205. CADHERIN.
SMARTiSM00112. CA. 6 hits.
[Graphical view]
SUPFAMiSSF49313. SSF49313. 5 hits.
PROSITEiPS00232. CADHERIN_1. 5 hits.
PS50268. CADHERIN_2. 6 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O93508-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIYWSFFMV FCMTSSVFCT TTKYFTFEED APGTEIGNLS QDLKIDPSED
60 70 80 90 100
PETSFKFIQT SNSIIDMRQM DGLLTVGEVI DREKLCQRSP QCLITFDVVA
110 120 130 140 150
FSKEKFQLIH VEIEVKDIND HSPQFTRNET HLDISEDAPL NSRFPLDVAV
160 170 180 190 200
DHDVGDNYIQ SYHISHNSHF VVEVSTREDG EKSAELVLIK SLDRETEDFY
210 220 230 240 250
TIEVTATDGG APQKSGSTTL YIRVLDFNDN SPTFEHSSLK VELSEDSPIG
260 270 280 290 300
SRVLKVHAFD PDAGINGEIV YGFVEGSPSE VTRVFQIDLI SGEVTLKDIV
310 320 330 340 350
DYETKKSYEL HIQASDLGAN SVSSTCRAIV DIIDVNDNAP EIIIKPMTST
360 370 380 390 400
SDGVAFITEA AAEESFVALI STSDKDSGPN GYVRTSLEGH EHFKLQQAYS
410 420 430 440 450
DTFMIITTTT LDRESISEYN LTVISEDLGT PPFKTVKHYT IRITDENDNP
460 470 480 490 500
PLFSKSIYDV SVIENNIPGS YMTTVVARDL DAGKNGKVSY SLVESKAPDG
510 520 530 540 550
SSISTFVSVD PHSGSLYTLR SFDFETLKDV QFSVKATDKG FPSLSSTTLI
560 570 580 590 600
QVRVVDDNDN FPYFTYPVLR NNSAEIPIPM NANTGYLALK VAAKDEDSGI
610 620 630 640 650
NSELNYHILE DEAKLFSIDK NTGEIILKRK LTASCGEILQ IYVSVVDGAR
660 670 680 690 700
EPLSSSANIR FIVTDTGAQE DQIVVLLRAE DDETFEFDLW SILVISFAGG
710 720 730 740 750
CVLLLTAIII LTVSCTIKRR RRSFGRDALY GWSPLSKNNP AGPSIYSGPN
760 770 780 790 800
GFLRSEGDSM QPCLYEDKSL SFEEKLFLPC KPFEQTFLWQ DEKYCLQRSG
810 820 830 840 850
TTDQLSVKDS GKGDSDFNDS DSDSSGGAQK PGLTTFQPLA RGSFCSSSDW
860 870 880 890 900
KIKPCVIQTR NLHAPPGSSY TLGFSRTPLY SHSHCSSHMW RDGAGGTLNT
910 920 930 940 950
QRPLQTFRSG TLPSYTAHQM RRAVMEIQEQ NEDLQDTLMI NAAAEVATTF
Length:950
Mass (Da):105,382
Last modified:November 1, 1998 - v1
Checksum:i6990953D82C6A52A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF042191 mRNA. Translation: AAC62385.1.
RefSeqiNP_571284.1. NM_131209.1.
UniGeneiDr.75833.

Genome annotation databases

GeneIDi30456.
KEGGidre:30456.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF042191 mRNA. Translation: AAC62385.1.
RefSeqiNP_571284.1. NM_131209.1.
UniGeneiDr.75833.

3D structure databases

ProteinModelPortaliO93508.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000112237.

Proteomic databases

PaxDbiO93508.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi30456.
KEGGidre:30456.

Organism-specific databases

CTDi5100.
ZFINiZDB-GENE-980526-242. pcdh8.

Phylogenomic databases

eggNOGiKOG3594. Eukaryota.
ENOG410XQHI. LUCA.
HOGENOMiHOG000220892.
HOVERGENiHBG054878.
KOiK16499.
PhylomeDBiO93508.

Miscellaneous databases

NextBioi20806851.

Family and domain databases

Gene3Di2.60.40.60. 6 hits.
InterProiIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
IPR013164. Cadherin_N.
[Graphical view]
PfamiPF00028. Cadherin. 5 hits.
PF08266. Cadherin_2. 1 hit.
[Graphical view]
PRINTSiPR00205. CADHERIN.
SMARTiSM00112. CA. 6 hits.
[Graphical view]
SUPFAMiSSF49313. SSF49313. 5 hits.
PROSITEiPS00232. CADHERIN_1. 5 hits.
PS50268. CADHERIN_2. 6 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Yamamoto A., De Robertis E.M.
    Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO93508_DANRE
AccessioniPrimary (citable) accession number: O93508
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: May 11, 2016
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.