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Protein
Submitted name:

GTP-binding protein

Gene

cRhoB

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-GGA-114604. GPVI-mediated activation cascade.
R-GGA-194840. Rho GTPase cycle.
R-GGA-416482. G alpha (12/13) signalling events.
R-GGA-416572. Sema4D induced cell migration and growth-cone collapse.
R-GGA-5625740. RHO GTPases activate PKNs.
R-GGA-5625900. RHO GTPases activate CIT.
R-GGA-5627117. RHO GTPases Activate ROCKs.
R-GGA-5663220. RHO GTPases Activate Formins.

Names & Taxonomyi

Protein namesi
Submitted name:
GTP-binding proteinImported
Submitted name:
GTPase cRhoBImported
Submitted name:
Ras homolog family member BImported
Gene namesi
Name:cRhoBImported
Synonyms:RHOBImported, rhoBImported
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MembraneSAAS annotation

Expressioni

Gene expression databases

BgeeiENSGALG00000016485.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000026544.

Family & Domainsi

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rho family.SAAS annotation

Phylogenomic databases

eggNOGiKOG0393. Eukaryota.
COG1100. LUCA.
GeneTreeiENSGT00760000119020.
HOGENOMiHOG000233974.
HOVERGENiHBG009351.
OMAiWEVFETA.
OrthoDBiEOG091G0QVS.
TreeFamiTF300837.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR003578. Small_GTPase_Rho.
PfamiView protein in Pfam
PF00071. Ras. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS51420. RHO. 1 hit.

Sequencei

Sequence statusi: Complete.

O93468-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAIRKKLVV VGDGACGKTC LLIVFSKDEF PEVYVPTVFE NYVADIEVDG
60 70 80 90 100
KQVELALWDT AGQEDYDRLR PLSYPDTDVI LMCFSVDSPD SLENIPEKWV
110 120 130 140 150
PEVKHFCPNV PIILVANKKD LRNDEHVRNE LARMKQEPVR TEDGRAMAIR
160 170 180 190
IQAYDYLECS AKTKEGVREV FETATRAALQ KRYGTQNGCI NCCKVL
Length:196
Mass (Da):22,205
Last modified:November 1, 1998 - v1
Checksum:iD5906EB99AD3F0A9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN04000306 Genomic DNA. No translation available.
U79758 mRNA. Translation: AAC18963.1.
AF098515 mRNA. Translation: AAD12257.1.
RefSeqiNP_990240.1. NM_204909.1.
UniGeneiGga.3852.

Genome annotation databases

EnsembliENSGALT00000026595; ENSGALP00000026544; ENSGALG00000016485.
GeneIDi395734.

Similar proteinsi

Entry informationi

Entry nameiO93468_CHICK
AccessioniPrimary (citable) accession number: O93468
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: November 22, 2017
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported