Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O93434

- RCN1_TAKRU

UniProt

O93434 - RCN1_TAKRU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Reticulocalbin-1

Gene

rcn1

Organism
Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Calcium bindingi83 – 94121; possibly ancestralPROSITE-ProRule annotationAdd
BLAST
Calcium bindingi119 – 130122PROSITE-ProRule annotationAdd
BLAST
Calcium bindingi170 – 181123; possibly ancestralPROSITE-ProRule annotationAdd
BLAST
Calcium bindingi207 – 218124PROSITE-ProRule annotationAdd
BLAST
Calcium bindingi248 – 259125PROSITE-ProRule annotationAdd
BLAST
Calcium bindingi284 – 295126PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Calcium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Reticulocalbin-1
Gene namesi
Name:rcn1
OrganismiTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Taxonomic identifieri31033 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataEupercariaTetraodontiformesTetradontoideaTetraodontidaeTakifugu
ProteomesiUP000005226: Unplaced

Subcellular locationi

Endoplasmic reticulum lumen PROSITE-ProRule annotation

GO - Cellular componenti

  1. endoplasmic reticulum Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence AnalysisAdd
BLAST
Chaini20 – 322303Reticulocalbin-1PRO_0000004147Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi44 – 441N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiO93434.

Interactioni

Protein-protein interaction databases

STRINGi31033.ENSTRUP00000016600.

Structurei

3D structure databases

ProteinModelPortaliO93434.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini70 – 10536EF-hand 1PROSITE-ProRule annotationAdd
BLAST
Domaini106 – 14136EF-hand 2PROSITE-ProRule annotationAdd
BLAST
Domaini157 – 19236EF-hand 3PROSITE-ProRule annotationAdd
BLAST
Domaini194 – 22936EF-hand 4PROSITE-ProRule annotationAdd
BLAST
Domaini235 – 27036EF-hand 5PROSITE-ProRule annotationAdd
BLAST
Domaini271 – 30636EF-hand 6PROSITE-ProRule annotationAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi319 – 3224Prevents secretion from ERPROSITE-ProRule annotation

Sequence similaritiesi

Belongs to the CREC family.Curated
Contains 6 EF-hand domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiNOG271367.
InParanoidiO93434.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR027241. Rcn1.
[Graphical view]
PANTHERiPTHR10827:SF17. PTHR10827:SF17. 1 hit.
PfamiPF13499. EF-hand_7. 1 hit.
[Graphical view]
SMARTiSM00054. EFh. 4 hits.
[Graphical view]
PROSITEiPS00018. EF_HAND_1. 4 hits.
PS50222. EF_HAND_2. 6 hits.
PS00014. ER_TARGET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O93434-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDVLGFICAV FLGTVVLHAK PTVRKDRVLY QDPELLRQAT NEDNNSFQYD
60 70 80 90 100
HEVFLGKEES KTFDQLSPEE SKDRLSKIVD RIDGDGNSYI TTDELKAWIK
110 120 130 140 150
RVQKRYVYEN VVKVWADYDL NKDNKISWEE YKQATYGYYL SNPEEFDETT
160 170 180 190 200
DQFSFKKMLP RDERRFKRAD LDGDSAANRE EFTSFLHPEE FEHMKDIVVL
210 220 230 240 250
ETLEDIDKNS DGHVDEDEYI ADMFAHEDRG PEPEWVKTER EQFSDFRDLN
260 270 280 290 300
KDGKMDLDEI RHWIMPQDYD HAQAEARHLV YESDKDKDQM LTKEEILDNW
310 320
NMFVGSQATN YGEDLTRNHD EL
Length:322
Mass (Da):38,207
Last modified:November 1, 1998 - v1
Checksum:i85F99C053AC34C5C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL021531 Genomic DNA. Translation: CAA16492.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL021531 Genomic DNA. Translation: CAA16492.1 .

3D structure databases

ProteinModelPortali O93434.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 31033.ENSTRUP00000016600.

Proteomic databases

PRIDEi O93434.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

eggNOGi NOG271367.
InParanoidi O93434.

Family and domain databases

Gene3Di 1.10.238.10. 2 hits.
InterProi IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR027241. Rcn1.
[Graphical view ]
PANTHERi PTHR10827:SF17. PTHR10827:SF17. 1 hit.
Pfami PF13499. EF-hand_7. 1 hit.
[Graphical view ]
SMARTi SM00054. EFh. 4 hits.
[Graphical view ]
PROSITEi PS00018. EF_HAND_1. 4 hits.
PS50222. EF_HAND_2. 6 hits.
PS00014. ER_TARGET. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequencing of the Fugu WAGR region from WT1 to PAX6: dramatic compaction and conservation of synteny with human chromosome 11p13."
    Miles C., Elgar G., Coles E., Kleinjan D.J., Van Heyningen V., Hastie N.
    Proc. Natl. Acad. Sci. U.S.A. 95:13068-13072(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiRCN1_TAKRU
AccessioniPrimary (citable) accession number: O93434
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 30, 2003
Last sequence update: November 1, 1998
Last modified: October 29, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3