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Protein
Submitted name:

Ephrin A-L1

Gene

efna1b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-DRE-2682334. EPH-Ephrin signaling.
R-DRE-3928663. EPHA-mediated growth cone collapse.
R-DRE-3928665. EPH-ephrin mediated repulsion of cells.

Names & Taxonomyi

Protein namesi
Submitted name:
Ephrin A-L1Imported
Submitted name:
Ephrin-A1bImported
Gene namesi
Name:efna1bImported
Synonyms:crsp6Imported, efna1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 16

Organism-specific databases

ZFINiZDB-GENE-041007-5. efna1b.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MembraneUniRule annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501083992321 – 229Sequence analysisAdd BLAST209

Expressioni

Gene expression databases

BgeeiENSDARG00000018787.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000012577.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 165Ephrin RBDInterPro annotationAdd BLAST146

Sequence similaritiesi

Belongs to the ephrin family.PROSITE-ProRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3858. Eukaryota.
ENOG4111FMJ. LUCA.
GeneTreeiENSGT00390000015107.
HOGENOMiHOG000234373.
HOVERGENiHBG051447.
KOiK05462.
OMAiCPHYEDD.
OrthoDBiEOG091G0K52.

Family and domain databases

CDDicd10425. Ephrin-A_Ectodomain. 1 hit.
Gene3Di2.60.40.420. 1 hit.
InterProiView protein in InterPro
IPR008972. Cupredoxin.
IPR031328. Ephrin.
IPR034252. Ephrin-A_Ecto.
IPR019765. Ephrin_CS.
IPR001799. Ephrin_RBD.
PANTHERiPTHR11304. PTHR11304. 1 hit.
PfamiView protein in Pfam
PF00812. Ephrin. 1 hit.
PRINTSiPR01347. EPHRIN.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002533. Ephrin. 1 hit.
SUPFAMiSSF49503. SSF49503. 1 hit.
PROSITEiView protein in PROSITE
PS01299. EPHRIN_RBD_1. 1 hit.
PS51551. EPHRIN_RBD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

O93431-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDFLWLLCVA VSVSAWYASA ERHSVYWNST NANFLWDDYT VDVRINDYLD
60 70 80 90 100
IICPHYAHGE IASQEAERYV LYMVELEDYE NCKPHSFDQL RWECSRPFAP
110 120 130 140 150
HAPEKFSEKF QRFTPFTLGK EFRQGESYYY ISKPLHHHGQ ECLRLKVDVV
160 170 180 190 200
GPHGSKNKKK MVEKVEEIEG KMAAGGVHNP SNRLPADDPI AMIPVVQRSV
210 220
GSSGVSVAPI SSFVTLLSVF ICLVLHQAS
Length:229
Mass (Da):26,115
Last modified:November 1, 1998 - v1
Checksum:i8684462F67AF6F5C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL935167 Genomic DNA. No translation available.
AJ006838 mRNA. Translation: CAA07264.1.
RefSeqiNP_957077.2. NM_200783.2.
UniGeneiDr.104284.

Genome annotation databases

EnsembliENSDART00000015956; ENSDARP00000012577; ENSDARG00000018787.
GeneIDi494151.
KEGGidre:494151.

Similar proteinsi

Entry informationi

Entry nameiO93431_DANRE
AccessioniPrimary (citable) accession number: O93431
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: September 27, 2017
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported