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Protein
Submitted name:

Ephrin A-L1

Gene

efna1b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-DRE-2682334. EPH-Ephrin signaling.
R-DRE-3928663. EPHA-mediated growth cone collapse.
R-DRE-3928665. EPH-ephrin mediated repulsion of cells.

Names & Taxonomyi

Protein namesi
Submitted name:
Ephrin A-L1Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:efna1bImported
Synonyms:crsp6Imported, efna1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 16

Organism-specific databases

ZFINiZDB-GENE-041007-5. efna1b.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

MembraneUniRule annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500877869121 – 229Sequence analysisAdd BLAST209

Expressioni

Gene expression databases

BgeeiENSDARG00000018787.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000012577.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 165Ephrin RBD (ephrin receptor-binding)InterPro annotationAdd BLAST146

Sequence similaritiesi

Belongs to the ephrin family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3858. Eukaryota.
ENOG4111FMJ. LUCA.
GeneTreeiENSGT00390000015107.
HOGENOMiHOG000234373.
HOVERGENiHBG051447.
KOiK05462.
OMAiNANFLWD.
OrthoDBiEOG091G0K52.

Family and domain databases

Gene3Di2.60.40.420. 1 hit.
InterProiIPR008972. Cupredoxin.
IPR031328. Ephrin.
IPR019765. Ephrin_CS.
IPR001799. Ephrin_RBD.
[Graphical view]
PANTHERiPTHR11304. PTHR11304. 1 hit.
PfamiPF00812. Ephrin. 1 hit.
[Graphical view]
PRINTSiPR01347. EPHRIN.
ProDomiPD002533. Ephrin. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF49503. SSF49503. 1 hit.
PROSITEiPS01299. EPHRIN_RBD_1. 1 hit.
PS51551. EPHRIN_RBD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O93431-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDFLWLLCVA VSVSAWYASA ERHSVYWNST NANFLWDDYT VDVRINDYLD
60 70 80 90 100
IICPHYAHGE IASQEAERYV LYMVELEDYE NCKPHSFDQL RWECSRPFAP
110 120 130 140 150
HAPEKFSEKF QRFTPFTLGK EFRQGESYYY ISKPLHHHGQ ECLRLKVDVV
160 170 180 190 200
GPHGSKNKKK MVEKVEEIEG KMAAGGVHNP SNRLPADDPI AMIPVVQRSV
210 220
GSSGVSVAPI SSFVTLLSVF ICLVLHQAS
Length:229
Mass (Da):26,115
Last modified:November 1, 1998 - v1
Checksum:i8684462F67AF6F5C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL935167 Genomic DNA. No translation available.
AJ006838 mRNA. Translation: CAA07264.1.
RefSeqiNP_957077.2. NM_200783.2.
UniGeneiDr.104284.

Genome annotation databases

EnsembliENSDART00000015956; ENSDARP00000012577; ENSDARG00000018787.
GeneIDi494151.
KEGGidre:494151.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL935167 Genomic DNA. No translation available.
AJ006838 mRNA. Translation: CAA07264.1.
RefSeqiNP_957077.2. NM_200783.2.
UniGeneiDr.104284.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000012577.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000015956; ENSDARP00000012577; ENSDARG00000018787.
GeneIDi494151.
KEGGidre:494151.

Organism-specific databases

CTDi494151.
ZFINiZDB-GENE-041007-5. efna1b.

Phylogenomic databases

eggNOGiKOG3858. Eukaryota.
ENOG4111FMJ. LUCA.
GeneTreeiENSGT00390000015107.
HOGENOMiHOG000234373.
HOVERGENiHBG051447.
KOiK05462.
OMAiNANFLWD.
OrthoDBiEOG091G0K52.

Enzyme and pathway databases

ReactomeiR-DRE-2682334. EPH-Ephrin signaling.
R-DRE-3928663. EPHA-mediated growth cone collapse.
R-DRE-3928665. EPH-ephrin mediated repulsion of cells.

Gene expression databases

BgeeiENSDARG00000018787.

Family and domain databases

Gene3Di2.60.40.420. 1 hit.
InterProiIPR008972. Cupredoxin.
IPR031328. Ephrin.
IPR019765. Ephrin_CS.
IPR001799. Ephrin_RBD.
[Graphical view]
PANTHERiPTHR11304. PTHR11304. 1 hit.
PfamiPF00812. Ephrin. 1 hit.
[Graphical view]
PRINTSiPR01347. EPHRIN.
ProDomiPD002533. Ephrin. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF49503. SSF49503. 1 hit.
PROSITEiPS01299. EPHRIN_RBD_1. 1 hit.
PS51551. EPHRIN_RBD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO93431_DANRE
AccessioniPrimary (citable) accession number: O93431
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: November 30, 2016
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.