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Protein
Submitted name:

Ephrin A-L1

Gene

efna1b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-DRE-2682334 EPH-Ephrin signaling
R-DRE-3928663 EPHA-mediated growth cone collapse
R-DRE-3928665 EPH-ephrin mediated repulsion of cells

Names & Taxonomyi

Protein namesi
Submitted name:
Ephrin A-L1Imported
Submitted name:
Ephrin-A1bImported
Gene namesi
Name:efna1bImported
Synonyms:crsp6Imported, efna1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 16

Organism-specific databases

ZFINiZDB-GENE-041007-5 efna1b

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MembraneUniRule annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501509683521 – 229Sequence analysisAdd BLAST209

Expressioni

Gene expression databases

BgeeiENSDARG00000018787

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000012577

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 165Ephrin RBDInterPro annotationAdd BLAST146

Sequence similaritiesi

Belongs to the ephrin family.PROSITE-ProRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3858 Eukaryota
ENOG4111FMJ LUCA
GeneTreeiENSGT00390000015107
HOGENOMiHOG000234373
HOVERGENiHBG051447
KOiK05462
OMAiCPHYEDD
OrthoDBiEOG091G0K52

Family and domain databases

CDDicd10425 Ephrin-A_Ectodomain, 1 hit
Gene3Di2.60.40.420, 1 hit
InterProiView protein in InterPro
IPR008972 Cupredoxin
IPR031328 Ephrin
IPR034252 Ephrin-A_Ecto
IPR019765 Ephrin_CS
IPR001799 Ephrin_RBD
PANTHERiPTHR11304 PTHR11304, 1 hit
PfamiView protein in Pfam
PF00812 Ephrin, 1 hit
PRINTSiPR01347 EPHRIN
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002533 Ephrin, 1 hit
SUPFAMiSSF49503 SSF49503, 1 hit
PROSITEiView protein in PROSITE
PS01299 EPHRIN_RBD_1, 1 hit
PS51551 EPHRIN_RBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

O93431-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDFLWLLCVA VSVSAWYASA ERHSVYWNST NANFLWDDYT VDVRINDYLD
60 70 80 90 100
IICPHYAHGE IASQEAERYV LYMVELEDYE NCKPHSFDQL RWECSRPFAP
110 120 130 140 150
HAPEKFSEKF QRFTPFTLGK EFRQGESYYY ISKPLHHHGQ ECLRLKVDVV
160 170 180 190 200
GPHGSKNKKK MVEKVEEIEG KMAAGGVHNP SNRLPADDPI AMIPVVQRSV
210 220
GSSGVSVAPI SSFVTLLSVF ICLVLHQAS
Length:229
Mass (Da):26,115
Last modified:November 1, 1998 - v1
Checksum:i8684462F67AF6F5C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL935167 Genomic DNA No translation available.
AJ006838 mRNA Translation: CAA07264.1
RefSeqiNP_957077.2, NM_200783.2
UniGeneiDr.104284

Genome annotation databases

EnsembliENSDART00000015956; ENSDARP00000012577; ENSDARG00000018787
GeneIDi494151
KEGGidre:494151

Similar proteinsi

Entry informationi

Entry nameiO93431_DANRE
AccessioniPrimary (citable) accession number: O93431
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: June 20, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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