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Protein
Submitted name:

Caspase-6

Gene
N/A
Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • cysteine-type endopeptidase activity Source: AgBase
  • cysteine-type peptidase activity Source: AgBase

GO - Biological processi

  • apoptotic chromosome condensation Source: AgBase
  • apoptotic DNA fragmentation Source: AgBase
  • apoptotic nuclear changes Source: AgBase
  • apoptotic process Source: AgBase
  • lens fiber cell differentiation Source: AgBase
  • proteolysis Source: AgBase

Protein family/group databases

MEROPSiC14.005.

Names & Taxonomyi

Protein namesi
Submitted name:
Caspase-6Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 179CASPASE_P20InterPro annotationAdd BLAST125
Domaini207 – 301CASPASE_P10InterPro annotationAdd BLAST95

Sequence similaritiesi

Belongs to the peptidase C14A family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3573. Eukaryota.
ENOG410ZQIE. LUCA.
HOGENOMiHOG000231878.
HOVERGENiHBG050802.
KOiK04396.

Family and domain databases

CDDicd00032. CASc. 1 hit.
InterProiView protein in InterPro
IPR029030. Caspase-like_dom.
IPR033139. Caspase_cys_AS.
IPR002138. Pept_C14_p10.
IPR001309. Pept_C14_p20.
IPR015917. Pept_C14A.
PRINTSiPR00376. IL1BCENZYME.
SMARTiView protein in SMART
SM00115. CASc. 1 hit.
SUPFAMiSSF52129. SSF52129. 1 hit.
PROSITEiView protein in PROSITE
PS01122. CASPASE_CYS. 1 hit.
PS50207. CASPASE_P10. 1 hit.
PS50208. CASPASE_P20. 1 hit.

Sequencei

Sequence statusi: Complete.

O93415-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGAERRPAA GRVQLDSKPT PTTTADGNQN ITEVDAFDKR RTFDPAEQYK
60 70 80 90 100
MNHQRRGVAL IFNHEHFFWH LRLPDRRGTL ADRNNLKRSL TDLGFEVRIF
110 120 130 140 150
DDLKAEDVLK KVFEASRDDY SNADCFVCVF LSHGENDHVY AYDAQIKIET
160 170 180 190 200
ITNMFRGDKC QSLVGKPKIF IIQACRGDKH DDPVLVQDSV DSKDETTVNQ
210 220 230 240 250
TEVDAAGVYT LPAGADFIMC YSVAQGYFSH RETVNGSWYI QDLCEALGKH
260 270 280 290 300
GSSLEFTELL TVVNRKVSHR KVDICRDINA IGKKQIPCFA SMLTKKLYFH

PKSK
Length:304
Mass (Da):34,534
Last modified:November 1, 1998 - v1
Checksum:i51CE31EBCAAE7383
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF082329 mRNA. Translation: AAC32378.1.
AF469049 Genomic DNA. Translation: AAL82386.1.
RefSeqiNP_990057.1. NM_204726.1.
UniGeneiGga.2960.

Genome annotation databases

GeneIDi395477.
KEGGigga:395477.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiO93415_CHICK
AccessioniPrimary (citable) accession number: O93415
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: July 5, 2017
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)